7S7F

STRUCTURE OF HLA-B*07:02 IN COMPLEX WITH DOT1L(998-1006) PHOSPHOPEPTIDE

Summary for 7S7F

• Entry DOI: 10.2210/pdb7s7f/pdb
• Related PRD ID: PRD_900003
• Descriptor: HLA class I histocompatibility antigen, B-7 alpha chain, Beta-2-microglobulin, Histone-lysine N-methyltransferase, H3 lysine-79 specific, ... (5 entities in total)
• Functional Keywords: hla, dot1l peptide, mhc-i, hla-b*07:02, hla-b7, immunity, immune system, phosphopeptide, cancer
• Biological source: Homo sapiens (Human); More
• Total number of polymer chains: 3
• Total formula weight: 45197.72

Authors

Patskovska, L.,Patskovsky, Y.,Nyovanie, S.,Natarajan, A.,Joshi, B.,Morin, B.,Brittsan, C.,Huber, O.,Gordon, S.,Michelet, X.,Schmitzberger, F.,Stein, R.,Findeis, M.,Hurwitz, A.,Van Dijk, M.,Buell, J.,Underwood, D.,Krogsgaard, M. (deposition date: 2021-09-15, release date: 2022-11-02, Last modification date: 2023-10-18)

• Primary citation: Patskovsky, Y.,Natarajan, A.,Patskovska, L.,Nyovanie, S.,Joshi, B.,Morin, B.,Brittsan, C.,Huber, O.,Gordon, S.,Michelet, X.,Schmitzberger, F.,Stein, R.B.,Findeis, M.A.,Hurwitz, A.,Van Dijk, M.,Chantzoura, E.,Yague, A.S.,Pollack Smith, D.,Buell, J.S.,Underwood, D.,Krogsgaard, M.; Molecular mechanism of phosphopeptide neoantigen immunogenicity.; Nat Commun, 14:3763-3763, 2023; PubMed: 37353482; DOI: 10.1038/s41467-023-39425-1

Experimental method

X-RAY DIFFRACTION (1.88 Å)