4RAU
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6A48
| Crystal structure of reelin N-terminal region | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, Reelin | 著者 | Nagae, M, Takagi, J. | 登録日 | 2018-06-19 | 公開日 | 2019-06-19 | 最終更新日 | 2023-11-22 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | Structural studies of reelin N-terminal region provides insights into a unique structural arrangement and functional multimerization. J.Biochem., 169, 2021
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4OJF
| Humanised 3D6 Fab complexed to amyloid beta 1-8 | 分子名称: | Amyloid beta A4 protein, Humanised 3D6 Fab Heavy Chain, Humanised 3D6 Fab Light Chain | 著者 | Miles, L.A, Crespi, G.A.N, Parker, M.W. | 登録日 | 2014-01-21 | 公開日 | 2015-01-28 | 最終更新日 | 2023-11-08 | 実験手法 | X-RAY DIFFRACTION (1.998 Å) | 主引用文献 | Crystallization and preliminary X-ray diffraction analysis of the Fab portion of the Alzheimer's disease immunotherapy candidate bapineuzumab complexed with amyloid-beta ACTA CRYSTALLOGR.,SECT.F, 70, 2014
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4OV5
| Structure of HLA-DR1 with a bound peptide with non-optimal alanine in the P1 pocket | 分子名称: | HLA class I histocompatibility antigen, A-2 alpha chain, HLA class II histocompatibility antigen, ... | 著者 | Trenh, P, Yin, L, Stern, L.J. | 登録日 | 2014-02-20 | 公開日 | 2014-07-16 | 最終更新日 | 2023-09-20 | 実験手法 | X-RAY DIFFRACTION (2.199 Å) | 主引用文献 | Susceptibility to HLA-DM Protein Is Determined by a Dynamic Conformation of Major Histocompatibility Complex Class II Molecule Bound with Peptide. J.Biol.Chem., 289, 2014
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1DN0
| STRUCTURE OF THE FAB FRAGMENT FROM A HUMAN IGM COLD AGGLUTININ | 分子名称: | IGM-KAPPA COLD AGGLUTININ (HEAVY CHAIN), IGM-KAPPA COLD AGGLUTININ (LIGHT CHAIN) | 著者 | Cauerhff, A, Braden, B, Carvalho, J.G, Leoni, J, Polikarpov, I, Goldbaum, F. | 登録日 | 1999-12-15 | 公開日 | 2001-01-24 | 最終更新日 | 2018-01-31 | 実験手法 | X-RAY DIFFRACTION (2.28 Å) | 主引用文献 | Three-dimensional structure of the Fab from a human IgM cold agglutinin. J.Immunol., 165, 2000
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4TSA
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1H0T
| An affibody in complex with a target protein: structure and coupled folding | 分子名称: | IMMUNOGLOBULIN G BINDING PROTEIN A, ZSPA-1 AFFIBODY | 著者 | Wahlberg, E, Lendel, C, Helgstrand, M, Allard, P, Dincbas-Renqvist, V, Hedqvist, A, Berglund, H, Nygren, P.-A, Hard, T. | 登録日 | 2002-06-27 | 公開日 | 2003-02-27 | 最終更新日 | 2024-05-15 | 実験手法 | SOLUTION NMR | 主引用文献 | An Affibody in Complex with a Target Protein: Structure and Coupled Folding Proc.Natl.Acad.Sci.USA, 100, 2003
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1H2O
| SOLUTION STRUCTURE OF THE MAJOR CHERRY ALLERGEN PRU AV 1 MUTANT E45W | 分子名称: | MAJOR ALLERGEN PRU AV 1 | 著者 | Neudecker, P, Lehmann, K, Nerkamp, J, Schweimer, K, Sticht, H, Boehm, M, Scheurer, S, Vieths, S, Roesch, P. | 登録日 | 2002-08-12 | 公開日 | 2003-08-28 | 最終更新日 | 2024-05-15 | 実験手法 | SOLUTION NMR | 主引用文献 | Mutational Epitope Analysis of Pru Av 1 and Api G 1, the Major Allergens of Cherry (Prunus Avium) and Celery (Apium Graveolens): Correlating Ige Reactivity with Three-Dimensional Structure Biochem.J., 376, 2003
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1CG2
| CARBOXYPEPTIDASE G2 | 分子名称: | CARBOXYPEPTIDASE G2, ZINC ION | 著者 | Rowsell, S, Pauptit, R.A, Tucker, A.D, Melton, R.G, Blow, D.M, Brick, P. | 登録日 | 1996-12-20 | 公開日 | 1997-12-24 | 最終更新日 | 2024-02-14 | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | 主引用文献 | Crystal structure of carboxypeptidase G2, a bacterial enzyme with applications in cancer therapy. Structure, 5, 1997
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7YD1
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7A6O
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7Y8J
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6ZPL
| Inward-open structure of human glycine transporter 1 in complex with a benzoylisoindoline inhibitor, sybody Sb_GlyT1#7 and bound Na and Cl ions. | 分子名称: | CHLORIDE ION, Endoglucanase H, SODIUM ION, ... | 著者 | Shahsavar, A, Stohler, P, Bourenkov, G, Zimmermann, I, Siegrist, M, Guba, W, Pinard, E, Sinning, S, Seeger, M.A, Schneider, T.R, Dawson, R.J.P, Nissen, P. | 登録日 | 2020-07-08 | 公開日 | 2021-03-17 | 最終更新日 | 2024-01-31 | 実験手法 | X-RAY DIFFRACTION (3.945 Å) | 主引用文献 | Structural insights into the inhibition of glycine reuptake. Nature, 591, 2021
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8GY5
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7Z8O
| Crystal structure of SARS-CoV-2 S RBD in complex with a stapled peptide | 分子名称: | 2,4,6-tris(chloromethyl)-1,3,5-triazine, GLYCEROL, Spike protein S1, ... | 著者 | Brear, P, Chen, L, Gaynor, K, Harman, M, Dods, R, Hyvonen, M. | 登録日 | 2022-03-18 | 公開日 | 2023-06-28 | 最終更新日 | 2024-02-07 | 実験手法 | X-RAY DIFFRACTION (0.96 Å) | 主引用文献 | Multivalent bicyclic peptides are an effective antiviral modality that can potently inhibit SARS-CoV-2. Nat Commun, 14, 2023
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6ZTD
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4ZNE
| IgG1 Fc-FcgammaRI ecd complex | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-alpha-D-mannopyranose-(1-3)-[2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-alpha-D-mannopyranose-(1-6)]alpha-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[beta-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... | 著者 | Oganesyan, V.Y, Dall'Acqua, W.F. | 登録日 | 2015-05-04 | 公開日 | 2015-11-11 | 最終更新日 | 2020-07-29 | 実験手法 | X-RAY DIFFRACTION (2.42 Å) | 主引用文献 | Structural insights into the interaction of human IgG1 with Fc gamma RI: no direct role of glycans in binding. Acta Crystallogr.,Sect.D, 71, 2015
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8IA8
| Cryo-EM structure of C3aR-Gi-scFv16 bound with E7 peptide | 分子名称: | ALA-SER-LYS-LEU-GLY-LEU-ALA-ARG, C3a anaphylatoxin chemotactic receptor, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, ... | 著者 | Liao, Q, Chen, G, Du, Y, Ye, R.D. | 登録日 | 2023-02-08 | 公開日 | 2023-05-24 | 実験手法 | ELECTRON MICROSCOPY (2.86 Å) | 主引用文献 | Cryo-EM structure of C3aR-Gi-scFv16 bound with E7 peptide To Be Published
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5ALC
| Ticagrelor antidote candidate Fab 72 in complex with ticagrelor | 分子名称: | ANTI-TICAGRELOR FAB 72, HEAVY CHAIN, LIGHT CHAIN, ... | 著者 | Buchanan, A, Newton, P, Pehrsson, S, Inghardt, T, Antonsson, T, Svensson, P, Sjogren, T, Oster, L, Janefeldt, A, Sandinge, A, Keyes, F, Austin, M, Spooner, J, Penney, M, Howells, G, Vaughan, T, Nylander, S. | 登録日 | 2015-03-07 | 公開日 | 2015-04-01 | 最終更新日 | 2024-01-10 | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | 主引用文献 | Structural and Functional Characterisation of a Specific Antidote for Ticagrelor. Blood, 125, 2015
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7YTE
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7YTD
| Cryo-EM structure of four human FcmR bound to IgM-Fc/J | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Fas apoptotic inhibitory molecule 3, Immunoglobulin J chain, ... | 著者 | Li, Y, Shen, H, Xiao, J. | 登録日 | 2022-08-14 | 公開日 | 2023-02-01 | 最終更新日 | 2023-05-03 | 実験手法 | ELECTRON MICROSCOPY (3.71 Å) | 主引用文献 | Immunoglobulin M perception by Fc mu R. Nature, 615, 2023
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7YSG
| Cryo-EM structure of human FcmR bound to sIgM | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Fas apoptotic inhibitory molecule 3, ... | 著者 | Li, Y, Shen, H, Xiao, J. | 登録日 | 2022-08-12 | 公開日 | 2023-02-01 | 最終更新日 | 2023-05-03 | 実験手法 | ELECTRON MICROSCOPY (3.18 Å) | 主引用文献 | Immunoglobulin M perception by Fc mu R. Nature, 615, 2023
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7YTC
| Cryo-EM structure of human FcmR bound to IgM-Fc/J | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Fas apoptotic inhibitory molecule 3, Immunoglobulin J chain, ... | 著者 | Li, Y, Shen, H, Xiao, J. | 登録日 | 2022-08-14 | 公開日 | 2023-02-01 | 最終更新日 | 2023-05-03 | 実験手法 | ELECTRON MICROSCOPY (3.39 Å) | 主引用文献 | Immunoglobulin M perception by Fc mu R. Nature, 615, 2023
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5B1C
| Crystal structure of DEN4 ED3 mutant with L387I | 分子名称: | Envelope protein E, SULFATE ION | 著者 | Kulkarni, M.R, Numoto, N, Ito, N, Kuroda, Y. | 登録日 | 2015-12-02 | 公開日 | 2016-02-24 | 最終更新日 | 2023-11-08 | 実験手法 | X-RAY DIFFRACTION (2.003 Å) | 主引用文献 | Modeling and experimental assessment of a buried Leu-Ile mutation in dengue envelope domain III Biochem.Biophys.Res.Commun., 471, 2016
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7AQG
| Crystal Structure of Small Molecule Inhibitor TM5484 Bound to Stabilized Active Plasminogen Activator Inhibitor-1 (PAI-1-W175F) | 分子名称: | 5-Chloro-2-[[2-[3-(furan-3-yl)anilino]-2-oxoacetyl]amino]benzoic acid, Plasminogen activator inhibitor 1, VHH-2g-42 (Nb42), ... | 著者 | Sillen, M, Strelkov, S.V, Declerck, P.J. | 登録日 | 2020-10-21 | 公開日 | 2021-02-24 | 最終更新日 | 2024-01-31 | 実験手法 | X-RAY DIFFRACTION (2.27 Å) | 主引用文献 | Structural Insight into the Two-Step Mechanism of PAI-1 Inhibition by Small Molecule TM5484. Int J Mol Sci, 22, 2021
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