7A6O

Crystal Structure of the Complex of the Recombinant Von Willebrand Factor AIM-A1 domain and VHH81 at 2.1 Angstrom resolution

Summary for 7A6O

Entry DOI	10.2210/pdb7a6o/pdb
Descriptor	von Willebrand factor, VHH81 Nanobody fragment, SULFATE ION, ... (4 entities in total)
Functional Keywords	thrombosis von willebrand factor a1 aim-a1 blood clotting complex vwf, blood clotting
Biological source	Homo sapiens (Human) More
Total number of polymer chains	2
Total formula weight	37399.70
Authors	Brown, A.K.,Emsley, J. (deposition date: 2020-08-25, release date: 2021-03-03, Last modification date: 2024-01-31)
Primary citation	Arce, N.A.,Cao, W.,Brown, A.K.,Legan, E.R.,Wilson, M.S.,Xu, E.R.,Berndt, M.C.,Emsley, J.,Zhang, X.F.,Li, R. Activation of von Willebrand factor via mechanical unfolding of its discontinuous autoinhibitory module. Nat Commun, 12:2360-2360, 2021 Cited by PubMed: 33883551 DOI: 10.1038/s41467-021-22634-x PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.117 Å)

Structure validation