5ALC
Ticagrelor antidote candidate Fab 72 in complex with ticagrelor
Summary for 5ALC
Entry DOI | 10.2210/pdb5alc/pdb |
Related | 5ALB |
Descriptor | ANTI-TICAGRELOR FAB 72, HEAVY CHAIN, ANTI-TICAGRELOR FAB 72, LIGHT CHAIN, Ticagrelor, ... (4 entities in total) |
Functional Keywords | immune system, antibody fragment, antidote, drug |
Biological source | HOMO SAPIENS (HUMAN) More |
Total number of polymer chains | 2 |
Total formula weight | 47823.10 |
Authors | Buchanan, A.,Newton, P.,Pehrsson, S.,Inghardt, T.,Antonsson, T.,Svensson, P.,Sjogren, T.,Oster, L.,Janefeldt, A.,Sandinge, A.,Keyes, F.,Austin, M.,Spooner, J.,Penney, M.,Howells, G.,Vaughan, T.,Nylander, S. (deposition date: 2015-03-07, release date: 2015-04-01, Last modification date: 2024-01-10) |
Primary citation | Buchanan, A.,Newton, P.,Pehrsson, S.,Inghardt, T.,Antonsson, T.,Svensson, P.,Sjogren, T.,Oster, L.,Janefeldt, A.,Sandinge, A.,Keyes, F.,Austin, M.,Spooner, J.,Gennemark, P.,Penney, M.,Howells, G.,Vaughan, T.,Nylander, S. Structural and Functional Characterisation of a Specific Antidote for Ticagrelor. Blood, 125:3484-, 2015 Cited by PubMed: 25788700DOI: 10.1182/BLOOD-2015-01-622928 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.7 Å) |
Structure validation
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