7VGP
 
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7PTY
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7VGO
 | | Hen egg lysozyme | | 分子名称: | CHLORIDE ION, Lysozyme C, SODIUM ION | | 著者 | Oda, M, Ikura, T, Ito, N. | | 登録日 | 2021-09-17 | | 公開日 | 2022-02-23 | | 最終更新日 | 2023-11-29 | | 実験手法 | X-RAY DIFFRACTION (1.2 Å) | | 主引用文献 | Structural Analysis of Hen Egg Lysozyme Refolded after Denaturation at Acidic pH.
Protein J., 41, 2022
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6LDH
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7UIS
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7PWH
 | | Structure of the dTDP-sugar epimerase StrM | | 分子名称: | 1,2-ETHANEDIOL, CHLORIDE ION, THYMIDINE-5'-DIPHOSPHATE, ... | | 著者 | Cross, A.R, Harmer, N.J, Isupov, M.N. | | 登録日 | 2021-10-06 | | 公開日 | 2022-04-20 | | 最終更新日 | 2024-01-31 | | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | | 主引用文献 | Spinning sugars in antigen biosynthesis: characterization of the Coxiella burnetii and Streptomyces griseus TDP-sugar epimerases.
J.Biol.Chem., 298, 2022
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7PWI
 | | Structure of the dTDP-sugar epimerase StrM | | 分子名称: | 1,2-ETHANEDIOL, CALCIUM ION, dTDP-4-keto-rhamnose 3,5-epimerase,dTDP-4-dehydrorhamnose 3,5-epimerase | | 著者 | Cross, A.R, Harmer, N.J, Isupov, M.N. | | 登録日 | 2021-10-06 | | 公開日 | 2022-04-20 | | 最終更新日 | 2024-01-31 | | 実験手法 | X-RAY DIFFRACTION (1.326 Å) | | 主引用文献 | Spinning sugars in antigen biosynthesis: characterization of the Coxiella burnetii and Streptomyces griseus TDP-sugar epimerases.
J.Biol.Chem., 298, 2022
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8VT0
 | | SPOT-RASTR - a cryo-EM specimen preparation technique that overcomes problems with preferred orientation and the air/water interface | | 分子名称: | Beta-galactosidase, MAGNESIUM ION | | 著者 | Esfahani, B.G, Randolph, P, Peng, R, Grant, T, Stroupe, M.E, Stagg, S.M. | | 登録日 | 2024-01-25 | | 公開日 | 2024-08-21 | | 実験手法 | ELECTRON MICROSCOPY (3.58 Å) | | 主引用文献 | SPOT-RASTR-A cryo-EM specimen preparation technique that overcomes problems with preferred orientation and the air/water interface.
Pnas Nexus, 3, 2024
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5V61
 | | Phospho-ERK2 bound to bivalent inhibitor SBP2 | | 分子名称: | 2-oxo-6,9,12,15-tetraoxa-3-azaoctadecan-18-oic acid, 5-(2-PHENYLPYRAZOLO[1,5-A]PYRIDIN-3-YL)-1H-PYRAZOLO[3,4-C]PYRIDAZIN-3-AMINE, GLYCEROL, ... | | 著者 | Lechtenberg, B.C, Riedl, S.J. | | 登録日 | 2017-03-15 | | 公開日 | 2017-07-26 | | 最終更新日 | 2023-11-15 | | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | | 主引用文献 | Structure-Guided Strategy for the Development of Potent Bivalent ERK Inhibitors.
ACS Med Chem Lett, 8, 2017
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6NVW
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7PJ4
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7PJ6
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7PPM
 | | SHP2 catalytic domain in complex with IRS1 (889-901) phosphopeptide (pSer-892, pTyr-896) | | 分子名称: | GLYCEROL, Insulin receptor substrate 1, Tyrosine-protein phosphatase non-receptor type 11,Tyrosine-protein phosphatase non-receptor type 11 | | 著者 | Sok, P, Zeke, A, Remenyi, A. | | 登録日 | 2021-09-14 | | 公開日 | 2022-09-07 | | 最終更新日 | 2024-01-31 | | 実験手法 | X-RAY DIFFRACTION (1.48 Å) | | 主引用文献 | Structural insights into the pSer/pThr dependent regulation of the SHP2 tyrosine phosphatase in insulin and CD28 signaling.
Nat Commun, 13, 2022
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7POZ
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7PPL
 | | SHP2 catalytic domain in complex with IRS1 (625-639) phosphopeptide (pTyr-632, pSer-636) | | 分子名称: | ETHANOL, GLYCEROL, Insulin receptor substrate 1, ... | | 著者 | Sok, P, Zeke, A, Remenyi, A. | | 登録日 | 2021-09-14 | | 公開日 | 2022-09-07 | | 最終更新日 | 2024-01-31 | | 実験手法 | X-RAY DIFFRACTION (1.53 Å) | | 主引用文献 | Structural insights into the pSer/pThr dependent regulation of the SHP2 tyrosine phosphatase in insulin and CD28 signaling.
Nat Commun, 13, 2022
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7TGN
 | | Crystal structure of DesD, the desferrioxamine synthetase from the Streptomyces violaceus salmycin biosynthetic pathway | | 分子名称: | 1,2-ETHANEDIOL, CITRATE ANION, Desferrioxamine synthetase DesD, ... | | 著者 | Patel, K.D, Gulick, A.M. | | 登録日 | 2022-01-07 | | 公開日 | 2022-07-06 | | 最終更新日 | 2024-02-28 | | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | | 主引用文献 | An acyl-adenylate mimic reveals the structural basis for substrate recognition by the iterative siderophore synthetase DesD.
J.Biol.Chem., 298, 2022
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7PL3
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6P4B
 | | HyHEL10 fab variant HyHEL10-4x (heavy chain mutations L4F, Y33H, S56N, and Y58F) bound to hen egg lysozyme variant HEL2x-flex (mutations R21Q, R73E, C76S, and C94S) | | 分子名称: | CHLORIDE ION, HyHEL10 Fab heavy chain, HyHEL10 Fab light chain, ... | | 著者 | Langley, D.B, Christ, D. | | 登録日 | 2019-05-27 | | 公開日 | 2020-05-27 | | 最終更新日 | 2023-10-11 | | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | | 主引用文献 | Conformational diversity facilitates antibody mutation trajectories and discrimination between foreign and self-antigens.
Proc.Natl.Acad.Sci.USA, 117, 2020
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3SBN
 | | trichovirin I-4A in polar environment at 0.9 Angstroem | | 分子名称: | ACETONITRILE, METHANOL, Trichovirin I-4A | | 著者 | Gessmann, R, Axford, D, Petratos, K. | | 登録日 | 2011-06-06 | | 公開日 | 2011-12-28 | | 最終更新日 | 2023-11-15 | | 実験手法 | X-RAY DIFFRACTION (0.9 Å) | | 主引用文献 | Four complete turns of a curved 310-helix at atomic resolution: The crystal structure of the peptaibol trichovirin I-4A in polar environment suggests a transition to alpha-helix for membrane function
Acta Crystallogr.,Sect.D, 68, 2012
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6LP1
 | | Crystal structure of acetate:succinate CoA transferase (ASCT) from Trypanosoma brucei. | | 分子名称: | CALCIUM ION, GLYCEROL, Succinyl-CoA:3-ketoacid-coenzyme A transferase | | 著者 | Mochizuki, K, Inaoka, D.K, Shiba, T, Fukuda, K, Kurasawa, H, Mazet, M, Millerioux, Y, Bringaud, F, Boshart, M, Balogun, E.O, Harada, S, Hirayama, K, Kita, K. | | 登録日 | 2020-01-08 | | 公開日 | 2020-10-07 | | 最終更新日 | 2023-11-29 | | 実験手法 | X-RAY DIFFRACTION (2.01 Å) | | 主引用文献 | The ASCT/SCS cycle fuels mitochondrial ATP and acetate production in Trypanosoma brucei.
Biochim Biophys Acta Bioenerg, 1861, 2020
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5T8A
 | | Recombinant cytotoxin-I from the venom of cobra N. oxiana | | 分子名称: | Cytotoxin 1 | | 著者 | Dubovskii, P.V, Dubinnyi, M.A, Shulepko, M.A, Lyukmanova, E.N, Dolgikh, D.A, Kirpichnikov, M.P, Efremov, R.G. | | 登録日 | 2016-09-07 | | 公開日 | 2017-09-20 | | 最終更新日 | 2019-05-08 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Structural and Dynamic "Portraits" of Recombinant and Native Cytotoxin I from Naja oxiana: How Close Are They?
Biochemistry, 56, 2017
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3TO4
 | | Structure of mouse Valpha14Vbeta2-mouseCD1d-alpha-Galactosylceramide | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Antigen-presenting glycoprotein CD1d1, ... | | 著者 | Patel, O, Rossjohn, J. | | 登録日 | 2011-09-04 | | 公開日 | 2011-12-14 | | 最終更新日 | 2023-09-13 | | 実験手法 | X-RAY DIFFRACTION (3.1 Å) | | 主引用文献 | Vbeta2 natural killer T cell antigen receptor-mediated recognition of CD1d-glycolipid antigen.
Proc.Natl.Acad.Sci.USA, 108, 2011
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8WTW
 | | Cryo-EM structure of noradrenaline transporter in complex with a x-MrlA analogue | | 分子名称: | CHLORIDE ION, MrlA, O-methyl-L-tyrosine, ... | | 著者 | Zhao, Y, Hu, T, Yu, Z. | | 登録日 | 2023-10-19 | | 公開日 | 2024-08-07 | | 最終更新日 | 2024-09-04 | | 実験手法 | ELECTRON MICROSCOPY (2.8 Å) | | 主引用文献 | Transport and inhibition mechanisms of the human noradrenaline transporter.
Nature, 632, 2024
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8WTU
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8WTV
 | | Cryo-EM structure of noradrenaline transporter in complex with noradrenaline | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, CHLORIDE ION, Noradrenaline, ... | | 著者 | Zhao, Y, Hu, T, Yu, Z. | | 登録日 | 2023-10-19 | | 公開日 | 2024-08-07 | | 最終更新日 | 2024-09-04 | | 実験手法 | ELECTRON MICROSCOPY (2.7 Å) | | 主引用文献 | Transport and inhibition mechanisms of the human noradrenaline transporter.
Nature, 632, 2024
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