8WTW

Cryo-EM structure of noradrenaline transporter in complex with a x-MrlA analogue

Summary for 8WTW

• Entry DOI: 10.2210/pdb8wtw/pdb
• EMDB information: 37844
• Descriptor: Sodium-dependent noradrenaline transporter, MrlA, CHLORIDE ION, ... (5 entities in total)
• Functional Keywords: norapinephrine transporter, mrla, structural protein
• Biological source: Homo sapiens (human); More
• Total number of polymer chains: 2
• Total formula weight: 65566.63

Authors

Zhao, Y.,Hu, T.,Yu, Z. (deposition date: 2023-10-19, release date: 2024-08-07, Last modification date: 2024-09-04)

• Primary citation: Hu, T.,Yu, Z.,Zhao, J.,Meng, Y.,Salomon, K.,Bai, Q.,Wei, Y.,Zhang, J.,Xu, S.,Dai, Q.,Yu, R.,Yang, B.,Loland, C.J.,Zhao, Y.; Transport and inhibition mechanisms of the human noradrenaline transporter.; Nature, 632:930-937, 2024; PubMed: 39085602; DOI: 10.1038/s41586-024-07638-z

Experimental method

ELECTRON MICROSCOPY (2.8 Å)