3RUG
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 3rug by Molmil](/molmil-images/mine/3rug) | Crystal structure of Valpha10-Vbeta8.1 NKT TCR in complex with CD1d-alphaglucosylceramide (C20:2) | 分子名称: | (11E,14E)-N-[(2S,3S,4R)-1-(alpha-D-glucopyranosyloxy)-3,4-dihydroxyoctadecan-2-yl]icosa-11,14-dienamide, 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... | 著者 | Patel, O, Rossjohn, J. | 登録日 | 2011-05-05 | 公開日 | 2011-08-03 | 最終更新日 | 2023-11-01 | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | 主引用文献 | A semi-invariant V(alpha)10(+) T cell antigen receptor defines a population of natural killer T cells with distinct glycolipid antigen-recognition properties Nat.Immunol., 12, 2011
|
|
4LLY
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 4lly by Molmil](/molmil-images/mine/4lly) | Crystal structure of Pertuzumab Clambda Fab with variable and constant domain redesigns (VRD2 and CRD2) at 1.6A | 分子名称: | GLYCEROL, MAGNESIUM ION, light chain Clambda, ... | 著者 | Pustilnik, A, Lewis, S.M, Wu, X, Sereno, A, Huang, F, Guntas, G, Leaver-Fay, A, Smith, E.M, Ho, C, Hansen-Estruch, C, Chamberlain, A.K, Truhlar, S.M, Kuhlman, B, Demarest, S.J, Atwell, S. | 登録日 | 2013-07-09 | 公開日 | 2014-01-29 | 最終更新日 | 2019-06-26 | 実験手法 | X-RAY DIFFRACTION (1.6 Å) | 主引用文献 | Generation of bispecific IgG antibodies by structure-based design of an orthogonal Fab interface. Nat.Biotechnol., 32, 2014
|
|
4LLU
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 4llu by Molmil](/molmil-images/mine/4llu) | Structure of Pertuzumab Fab with light chain Clambda at 2.16A | 分子名称: | ACETATE ION, Light chain CLAMBDA, PERTUZUMAB FAB Heavy chain, ... | 著者 | Pustilnik, A, Lewis, S.M, Wu, X, Sereno, A, Huang, F, Guntas, G, Leaver-Fay, A, Smith, E.M, Ho, C, Hansen-Estruch, C, Chamberlain, A.K, Truhlar, S.M, Kuhlman, B, Demarest, S.J, Atwell, S. | 登録日 | 2013-07-09 | 公開日 | 2014-01-29 | 最終更新日 | 2023-09-20 | 実験手法 | X-RAY DIFFRACTION (2.16 Å) | 主引用文献 | Generation of bispecific IgG antibodies by structure-based design of an orthogonal Fab interface. Nat.Biotechnol., 32, 2014
|
|
3SDC
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 3sdc by Molmil](/molmil-images/mine/3sdc) | |
3SDA
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 3sda by Molmil](/molmil-images/mine/3sda) | |
4R26
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 4r26 by Molmil](/molmil-images/mine/4r26) | Crystal structure of human Fab PGT124, a broadly neutralizing and potent HIV-1 neutralizing antibody | 分子名称: | GLYCEROL, PGR124-Light Chain, PGT124-Heavy Chain | 著者 | Garces, F, Kong, L, Wilson, I.A. | 登録日 | 2014-08-08 | 公開日 | 2014-10-08 | 最終更新日 | 2017-06-21 | 実験手法 | X-RAY DIFFRACTION (2.4969 Å) | 主引用文献 | Structural Evolution of Glycan Recognition by a Family of Potent HIV Antibodies. Cell(Cambridge,Mass.), 159, 2014
|
|
4MNG
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 4mng by Molmil](/molmil-images/mine/4mng) | Structure of the DP10.7 TCR with CD1d-sulfatide | 分子名称: | (15Z)-N-((1S,2R,3E)-2-HYDROXY-1-{[(3-O-SULFO-BETA-D-GALACTOPYRANOSYL)OXY]METHYL}HEPTADEC-3-ENYL)TETRACOS-15-ENAMIDE, 2-acetamido-2-deoxy-beta-D-glucopyranose, Beta-2-microglobulin, ... | 著者 | Luoma, A.M, Adams, E.J. | 登録日 | 2013-09-10 | 公開日 | 2013-12-18 | 最終更新日 | 2023-09-20 | 実験手法 | X-RAY DIFFRACTION (3.0058 Å) | 主引用文献 | Crystal Structure of V delta 1 T Cell Receptor in Complex with CD1d-Sulfatide Shows MHC-like Recognition of a Self-Lipid by Human gamma delta T Cells. Immunity, 39, 2013
|
|
4MQ7
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 4mq7 by Molmil](/molmil-images/mine/4mq7) | Structure of human CD1d-sulfatide | 分子名称: | (15Z)-N-((1S,2R,3E)-2-HYDROXY-1-{[(3-O-SULFO-BETA-D-GALACTOPYRANOSYL)OXY]METHYL}HEPTADEC-3-ENYL)TETRACOS-15-ENAMIDE, 2-acetamido-2-deoxy-beta-D-glucopyranose, Antigen-presenting glycoprotein CD1d, ... | 著者 | Luoma, A.M, Adams, E.J. | 登録日 | 2013-09-15 | 公開日 | 2013-12-18 | 最終更新日 | 2023-09-20 | 実験手法 | X-RAY DIFFRACTION (2.6032 Å) | 主引用文献 | Crystal Structure of V delta 1 T Cell Receptor in Complex with CD1d-Sulfatide Shows MHC-like Recognition of a Self-Lipid by Human gamma delta T Cells. Immunity, 39, 2013
|
|
4LFH
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 4lfh by Molmil](/molmil-images/mine/4lfh) | Crystal Structure of 9C2 TCR | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 9C2 TCR delta chain, 9C2 TCR gamma chain, ... | 著者 | Uldrich, A.P, Le Nours, J, Pellicci, D.G, Gras, S, Rossjohn, J, Godfrey, D.I. | 登録日 | 2013-06-26 | 公開日 | 2013-10-02 | 最終更新日 | 2023-09-20 | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | 主引用文献 | CD1d-lipid antigen recognition by the gamma delta TCR. Nat.Immunol., 14, 2013
|
|
3RTQ
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 3rtq by Molmil](/molmil-images/mine/3rtq) | Structure of the mouse CD1d-HS44-iNKT TCR complex | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Antigen-presenting glycoprotein CD1d1, ... | 著者 | Yu, E.D, Zajonc, D.M. | 登録日 | 2011-05-03 | 公開日 | 2012-02-22 | 最終更新日 | 2020-07-29 | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | 主引用文献 | Structural and functional characterization of a novel nonglycosidic type I NKT agonist with immunomodulatory properties. J.Immunol., 188, 2012
|
|
3RY6
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 3ry6 by Molmil](/molmil-images/mine/3ry6) | Complex of fcgammariia (CD32) and the FC of human IGG1 | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, GLYCEROL, Ig gamma-1 chain C region, ... | 著者 | Ramsland, P.A, Farrugia, W, Scott, A.M, Hogarth, P.M. | 登録日 | 2011-05-11 | 公開日 | 2011-08-31 | 最終更新日 | 2023-09-13 | 実験手法 | X-RAY DIFFRACTION (3.8 Å) | 主引用文献 | Structural Basis for Fc{gamma}RIIa Recognition of Human IgG and Formation of Inflammatory Signaling Complexes. J.Immunol., 187, 2011
|
|
3SDD
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 3sdd by Molmil](/molmil-images/mine/3sdd) | |
4R7D
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 4r7d by Molmil](/molmil-images/mine/4r7d) | Fab Hu 15C1 | 分子名称: | Fab Hu 15C1 Heavy chain, Fab Hu 15C1 Light chain | 著者 | Loyau, J, Didelot, G, Malinge, P, Ravn, U, Magistrelli, G, Depoisier, J.F, Kosco-Vilbois, M, Fischer, N, Thore, S, Rousseau, F. | 登録日 | 2014-08-27 | 公開日 | 2015-07-29 | 最終更新日 | 2015-08-26 | 実験手法 | X-RAY DIFFRACTION (2.753 Å) | 主引用文献 | Robust Antibody-Antigen Complexes Prediction Generated by Combining Sequence Analyses, Mutagenesis, In Vitro Evolution, X-ray Crystallography and In Silico Docking. J.Mol.Biol., 427, 2015
|
|
4LLW
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 4llw by Molmil](/molmil-images/mine/4llw) | Crystal structure of Pertuzumab Clambda Fab with variable domain redesign (VRD2) at 1.95A | 分子名称: | SULFATE ION, light chain Clambda, mutated Pertuzumab Fab heavy chain | 著者 | Pustilnik, A, Lewis, S.M, Wu, X, Sereno, A, Huang, F, Guntas, G, Leaver-Fay, A, Smith, E.M, Ho, C, Hansen-Estruch, C, Chamberlain, A.K, Truhlar, S.M, Kuhlman, B, Demarest, S.J, Atwell, S. | 登録日 | 2013-07-09 | 公開日 | 2014-01-29 | 最終更新日 | 2019-06-26 | 実験手法 | X-RAY DIFFRACTION (1.95 Å) | 主引用文献 | Generation of bispecific IgG antibodies by structure-based design of an orthogonal Fab interface. Nat.Biotechnol., 32, 2014
|
|
3RZC
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 3rzc by Molmil](/molmil-images/mine/3rzc) | Structure of the self-antigen iGb3 bound to mouse CD1d and in complex with the iNKT TCR | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Antigen-presenting glycoprotein CD1d1, Beta-2-microglobulin, ... | 著者 | Yu, E.D, Girardi, E, Wang, J, Zajonc, D.M. | 登録日 | 2011-05-11 | 公開日 | 2011-08-24 | 最終更新日 | 2020-07-29 | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | 主引用文献 | Cutting Edge: Structural Basis for the Recognition of {beta}-Linked Glycolipid Antigens by Invariant NKT Cells. J.Immunol., 187, 2011
|
|
3S6C
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 3s6c by Molmil](/molmil-images/mine/3s6c) | Structure of human CD1e | 分子名称: | Beta-2-microglobulin, T-cell surface glycoprotein CD1e, membrane-associated, ... | 著者 | Garcia-Alles, L.F, Maveyraud, L, Tranier, S, Mourey, L. | 登録日 | 2011-05-25 | 公開日 | 2011-07-20 | 最終更新日 | 2020-07-29 | 実験手法 | X-RAY DIFFRACTION (2.9 Å) | 主引用文献 | Crystal structure of human CD1e reveals a groove suited for lipid-exchange processes. Proc.Natl.Acad.Sci.USA, 108, 2011
|
|
4P3D
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 4p3d by Molmil](/molmil-images/mine/4p3d) | MT1-MMP:Fab complex (Form II) | 分子名称: | 1,2-ETHANEDIOL, 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, CHLORIDE ION, ... | 著者 | Rozenberg, H, Udi, Y, Sagi, I. | 登録日 | 2014-03-07 | 公開日 | 2014-12-17 | 最終更新日 | 2023-09-27 | 実験手法 | X-RAY DIFFRACTION (1.949 Å) | 主引用文献 | Inhibition mechanism of membrane metalloprotease by an exosite-swiveling conformational antibody. Structure, 23, 2015
|
|
4PB0
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 4pb0 by Molmil](/molmil-images/mine/4pb0) | Structure of the Fab fragment of the anti-Francisella tularensis GroEL antibody Ab53 | 分子名称: | 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, Ab53 heavy chain, Ab53 light chain, ... | 著者 | Lu, Z, Rynkiewicz, M.J, Seaton, B.A, Sharon, J. | 登録日 | 2014-04-10 | 公開日 | 2014-07-16 | 最終更新日 | 2023-12-27 | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | 主引用文献 | B-Cell Epitopes in GroEL of Francisella tularensis. Plos One, 9, 2014
|
|
4PUB
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 4pub by Molmil](/molmil-images/mine/4pub) | Crystal structure of Fab DX-2930 | 分子名称: | CHLORIDE ION, DX-2930 HEAVY CHAIN, DX-2930 LIGHT CHAIN | 著者 | Abendroth, J, Edwards, T.E, Nixon, A, Ladner, R. | 登録日 | 2014-03-12 | 公開日 | 2014-07-09 | 最終更新日 | 2023-09-20 | 実験手法 | X-RAY DIFFRACTION (1.75 Å) | 主引用文献 | Inhibition of plasma kallikrein by a highly specific active site blocking antibody. J.Biol.Chem., 289, 2014
|
|
4LHU
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 4lhu by Molmil](/molmil-images/mine/4lhu) | Crystal Structure of 9C2 TCR bound to CD1d | 分子名称: | (15Z)-N-[(2S,3S,4R)-1-(alpha-D-galactopyranosyloxy)-3,4-dihydroxyoctadecan-2-yl]tetracos-15-enamide, 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... | 著者 | Uldrich, A.P, Le Nours, J, Pellicci, D.G, Gras, S, Rossjohn, J, Godfrey, D.I. | 登録日 | 2013-07-01 | 公開日 | 2013-10-02 | 最終更新日 | 2023-09-20 | 実験手法 | X-RAY DIFFRACTION (2.87 Å) | 主引用文献 | CD1d-lipid antigen recognition by the gamma delta TCR. Nat.Immunol., 14, 2013
|
|
3SCM
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 3scm by Molmil](/molmil-images/mine/3scm) | |
3SDX
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 3sdx by Molmil](/molmil-images/mine/3sdx) | Crystal structure of human autoreactive-Valpha24 NKT TCR in complex with CD1d-beta-galactosylceramide | 分子名称: | Antigen-presenting glycoprotein CD1d, Beta-2-microglobulin, N-[(2S,3R)-1-(beta-D-galactopyranosyloxy)-3-hydroxyoctadec-4-en-2-yl]tetracosanamide, ... | 著者 | Clarke, A.J, Patel, O, Rossjohn, J. | 登録日 | 2011-06-09 | 公開日 | 2011-10-05 | 実験手法 | X-RAY DIFFRACTION (3.12 Å) | 主引用文献 | Recognition of beta-linked self glycolipids mediated by natural killer T cell antigen receptors Nat.Immunol., 12, 2011
|
|
3T1F
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 3t1f by Molmil](/molmil-images/mine/3t1f) | Crystal structure of the mouse CD1d-Glc-DAG-s2 complex | 分子名称: | (2S)-1-(alpha-D-glucopyranosyloxy)-3-(hexadecanoyloxy)propan-2-yl (11Z)-octadec-11-enoate, 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... | 著者 | Girardi, E, Zajonc, D.M. | 登録日 | 2011-07-21 | 公開日 | 2011-09-21 | 最終更新日 | 2020-07-29 | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | 主引用文献 | Invariant natural killer T cells recognize glycolipids from pathogenic Gram-positive bacteria. Nat.Immunol., 12, 2011
|
|
4K3D
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 4k3d by Molmil](/molmil-images/mine/4k3d) | Crystal structure of bovine antibody BLV1H12 with ultralong CDR H3 | 分子名称: | BOVINE ANTIBODY WITH ULTRALONG CDR H3, HEAVY CHAIN, LIGHT CHAIN, ... | 著者 | Ekiert, D.C, Wang, F, Wilson, I.A. | 登録日 | 2013-04-10 | 公開日 | 2013-06-19 | 最終更新日 | 2023-09-20 | 実験手法 | X-RAY DIFFRACTION (1.85 Å) | 主引用文献 | Reshaping antibody diversity. Cell(Cambridge,Mass.), 153, 2013
|
|
4OCY
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 4ocy by Molmil](/molmil-images/mine/4ocy) | Fab for methotrexate (unbound apo) | 分子名称: | Fab ADD058 Heavy Chain, Fab ADD058 Light Chain | 著者 | Longenecker, K.L, Judge, R.A, Gayda, S, Manoj, S, Saldana, S, Ruan, Q, Swift, K, Tetin, S. | 登録日 | 2014-01-09 | 公開日 | 2014-07-02 | 最終更新日 | 2017-11-22 | 実験手法 | X-RAY DIFFRACTION (2.79 Å) | 主引用文献 | Water channel in the binding site of a high affinity anti-methotrexate antibody. Biochemistry, 53, 2014
|
|