3RY6

Complex of fcgammariia (CD32) and the FC of human IGG1

Summary for 3RY6

• Entry DOI: 10.2210/pdb3ry6/pdb
• Related: 3RY4 3RY5
• Descriptor: Ig gamma-1 chain C region, Low affinity immunoglobulin gamma Fc region receptor II-a, N-acetyl-alpha-neuraminic acid-(2-6)-beta-D-galactopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-alpha-D-mannopyranose-(1-3)-[2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-alpha-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[beta-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-alpha-D-glucopyranose, ... (7 entities in total)
• Functional Keywords: fc receptor, cd32, immunoglobulin superfamily, high responder polymorphism, human igg1, therapeutic antibody, glycoprotein, immunoglobulin c region, immunoglobulin domain, cell membrane, igg-binding protein, membrane, phosphoprotein, receptor, transmembrane, immune system
• Biological source: Homo sapiens (human); More
• Total number of polymer chains: 3
• Total formula weight: 73303.44

Authors

Ramsland, P.A.,Farrugia, W.,Scott, A.M.,Hogarth, P.M. (deposition date: 2011-05-11, release date: 2011-08-31, Last modification date: 2023-09-13)

• Primary citation: Ramsland, P.A.,Farrugia, W.,Bradford, T.M.,Sardjono, C.T.,Esparon, S.,Trist, H.M.,Powell, M.S.,Tan, P.S.,Cendron, A.C.,Wines, B.D.,Scott, A.M.,Hogarth, P.M.; Structural Basis for Fc{gamma}RIIa Recognition of Human IgG and Formation of Inflammatory Signaling Complexes.; J.Immunol., 187:3208-3217, 2011; PubMed: 21856937; DOI: 10.4049/jimmunol.1101467

Experimental method

X-RAY DIFFRACTION (3.8 Å)