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8E7W
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RsTSPO A139T with Heme
分子名称: (2R)-2,3-dihydroxypropyl (9Z)-octadec-9-enoate, (2S)-3-{[{[(2S)-2,3-DIHYDROXYPROPYL]OXY}(HYDROXY)PHOSPHORYL]OXY}-2-[(6E)-HEXADEC-6-ENOYLOXY]PROPYL (8E)-OCTADEC-8-ENOATE, PROTOPORPHYRIN IX CONTAINING FE, ...
著者Liu, J, Hiser, C, Li, F, Garavito, R, Ferguson-Miller, S.
登録日2022-08-25
公開日2023-03-29
最終更新日2023-10-25
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献New TSPO Crystal Structures of Mutant and Heme-Bound Forms with Altered Flexibility, Ligand Binding, and Porphyrin Degradation Activity.
Biochemistry, 62, 2023
2O0F
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Docking of the modified RF3 X-ray structure into cryo-EM map of E.coli 70S ribosome bound with RF3
分子名称: Peptide chain release factor 3
著者Gao, H, Zhou, Z, Rawat, U, Huang, C, Bouakaz, L, Wang, C, Liu, Y, Zavialov, A, Gursky, R, Sanyal, S, Ehrenberg, M, Frank, J, Song, H.
登録日2006-11-27
公開日2007-07-24
最終更新日2023-12-27
実験手法ELECTRON MICROSCOPY (15.5 Å)
主引用文献RF3 induces ribosomal conformational changes responsible for dissociation of class I release factors
Cell(Cambridge,Mass.), 129, 2007
5JSN
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Bcl2-inhibitor complex
分子名称: Apoptosis regulator Bcl-2, Bcl2 inhibitor
著者Shen, B.W, Stoddard, B.L.
登録日2016-05-09
公開日2016-11-16
最終更新日2024-03-06
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Computationally designed high specificity inhibitors delineate the roles of BCL2 family proteins in cancer.
Elife, 5, 2016
2NXJ
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T.thermophilus ribosomal protein L11 methyltransferase (PrmA) in space group P 21 21 2
分子名称: Ribosomal protein L11 methyltransferase
著者Demirci, H, Gregory, S.T, Dahlberg, A.E, Jogl, G.
登録日2006-11-17
公開日2006-12-26
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Recognition of ribosomal protein L11 by the protein trimethyltransferase PrmA.
Embo J., 26, 2007
2NTS
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Crystal Structure of SEK-hVb5.1
分子名称: Staphylococcal enterotoxin K, TRBC1 protein
著者Gunther, S, Varma, A.K, Moza, B, Sundberg, E.J.
登録日2006-11-08
公開日2007-06-26
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献A novel loop domain in superantigens extends their T cell receptor recognition site
J.Mol.Biol., 371, 2007
2NXF
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Crystal Structure of a dimetal phosphatase from Danio rerio LOC 393393
分子名称: ETHANOL, PHOSPHATE ION, Putative dimetal phosphatase, ...
著者Bitto, E, Wesenberg, G.E, Phillips Jr, G.N, McCoy, J.G, Bingman, C.A, Center for Eukaryotic Structural Genomics (CESG)
登録日2006-11-17
公開日2006-12-12
最終更新日2023-12-27
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献Crystal Structure of a dimetal phosphatase from Danio rerio LOC 393393
To be Published
2O2F
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Solution structure of the anti-apoptotic protein Bcl-2 in complex with an acyl-sulfonamide-based ligand
分子名称: 4-(4-BENZYL-4-METHOXYPIPERIDIN-1-YL)-N-[(4-{[1,1-DIMETHYL-2-(PHENYLTHIO)ETHYL]AMINO}-3-NITROPHENYL)SULFONYL]BENZAMIDE, Apoptosis regulator Bcl-2
著者Bruncko, M, Oost, T.K, Belli, B.A, Ding, H, Joseph, M.K, Kunzer, A, Martineau, D, McClellan, W.J, Mitten, M, Ng, S.C, Nimmer, P.M, Oltersdorf, T, Park, C.M, Petros, A.M, Shoemaker, A.R, Song, X, Wang, X, Wendt, M.D, Zhang, H, Fesik, S.W, Rosenberg, S.H, Elmore, S.W.
登録日2006-11-29
公開日2007-02-27
最終更新日2023-12-27
実験手法SOLUTION NMR
主引用文献Studies Leading to Potent, Dual Inhibitors of Bcl-2 and Bcl-xL.
J.Med.Chem., 50, 2007
2O57
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Crystal Structure of a putative sarcosine dimethylglycine methyltransferase from Galdieria sulphuraria
分子名称: putative sarcosine dimethylglycine methyltransferase
著者Mccoy, J.G, Wesenberg, G.E, Phillips Jr, G.N, Bitto, E, Bingman, C.A, Center for Eukaryotic Structural Genomics (CESG)
登録日2006-12-05
公開日2006-12-19
最終更新日2023-12-27
実験手法X-RAY DIFFRACTION (1.946 Å)
主引用文献Crystal Structure of a putative sarcosine dimethylglycine methyltransferase from Galdieria sulphuraria
To be Published
2PE5
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Crystal Structure of the Lac Repressor bound to ONPG in repressed state
分子名称: 2-nitrophenyl beta-D-galactopyranoside, DNA (5'-D(*DAP*DAP*DTP*DTP*DGP*DTP*DGP*DAP*DGP*DCP*DGP*DCP*DTP*DCP*DAP*DCP*DAP*DAP*DTP*DT)-3'), Lactose operon repressor
著者Daber, R, Stayrook, S.E, Rosenberg, A, Lewis, M.
登録日2007-04-02
公開日2008-03-18
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (3.5 Å)
主引用文献Structural analysis of lac repressor bound to allosteric effectors
J.Mol.Biol., 370, 2007
3MTG
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BU of 3mtg by Molmil
Crystal structure of human S-adenosyl homocysteine hydrolase-like 1 protein
分子名称: NICOTINAMIDE-ADENINE-DINUCLEOTIDE, Putative adenosylhomocysteinase 2
著者Wisniewska, M, Siponen, M.I, Arrowsmith, C.H, Berglund, H, Bountra, C, Collins, R, Edwards, A.M, Flodin, S, Flores, A, Graslund, S, Hammarstrom, M, Johansson, I, Karlberg, T, Kotenyova, T, Moche, M, Nordlund, P, Nyman, T, Persson, C, Schutz, P, Thorsell, A.G, Tresaugues, L, van der Berg, S, Wahlberg, E, Weigelt, J, Welin, M, Schuler, H, Structural Genomics Consortium (SGC)
登録日2010-04-30
公開日2010-05-26
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (2.64 Å)
主引用文献Crystal structure of human S-adenosyl homocysteine hydrolase-like 1 protein
TO BE PUBLISHED
2OUT
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BU of 2out by Molmil
Solution Structure of HI1506, a Novel Two Domain Protein from Haemophilus influenzae
分子名称: Mu-like prophage FluMu protein gp35, Protein HI1507 in Mu-like prophage FluMu region
著者Sari, N, He, Y, Doseeva, V, Surabian, K, Schwarz, F, Herzberg, O, Orban, J, Structure 2 Function Project (S2F)
登録日2007-02-12
公開日2007-05-01
最終更新日2024-05-22
実験手法SOLUTION NMR
主引用文献Solution structure of HI1506, a novel two-domain protein from Haemophilus influenzae.
Protein Sci., 16, 2007
6GG8
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Mineralocorticoid receptor in complex with (s)-13
分子名称: (4S)-2-METHYL-2,4-PENTANEDIOL, Mineralocorticoid receptor, Nuclear receptor coactivator 1, ...
著者Edman, K, Aagaard, A, Tangefjord, S.
登録日2018-05-03
公開日2019-01-09
最終更新日2024-01-17
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Identification of Mineralocorticoid Receptor Modulators with Low Impact on Electrolyte Homeostasis but Maintained Organ Protection.
J.Med.Chem., 62, 2019
2P5M
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BU of 2p5m by Molmil
C-terminal domain hexamer of AhrC bound with L-arginine
分子名称: ARGININE, Arginine repressor
著者Garnett, J.A, Baumberg, S, Stockley, P.G, Phillips, S.E.V.
登録日2007-03-15
公開日2007-10-30
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (1.95 Å)
主引用文献Structure of the C-terminal effector-binding domain of AhrC bound to its corepressor L-arginine.
Acta Crystallogr.,Sect.F, 63, 2007
2ODJ
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BU of 2odj by Molmil
Crystal structure of the outer membrane protein OprD from Pseudomonas aeruginosa
分子名称: (HYDROXYETHYLOXY)TRI(ETHYLOXY)OCTANE, Porin D
著者Biswas, S, van den Berg, B.
登録日2006-12-22
公開日2007-10-16
最終更新日2023-12-27
実験手法X-RAY DIFFRACTION (2.9 Å)
主引用文献Structural insight into OprD substrate specificity.
Nat.Struct.Mol.Biol., 14, 2007
2NTT
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Crystal Structure of SEK
分子名称: 1,2-ETHANEDIOL, CHLORIDE ION, Staphylococcal enterotoxin K
著者Gunther, S, Varma, A.K, Moza, B, Sundberg, E.J.
登録日2006-11-08
公開日2007-06-26
最終更新日2024-04-03
実験手法X-RAY DIFFRACTION (1.561 Å)
主引用文献A novel loop domain in superantigens extends their T cell receptor recognition site
J.Mol.Biol., 371, 2007
2NVZ
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BU of 2nvz by Molmil
RNA Polymerase II elongation complex with UTP, updated 11/2006
分子名称: 28-MER DNA template strand, 5'-D(*CP*TP*GP*CP*TP*TP*AP*TP*CP*GP*GP*TP*AP*G)-3', 5'-R(*AP*UP*CP*GP*AP*GP*AP*GP*GP*A)-3', ...
著者Wang, D, Bushnell, D.A, Westover, K.D, Kaplan, C.D, Kornberg, R.D.
登録日2006-11-14
公開日2006-12-19
最終更新日2023-10-25
実験手法X-RAY DIFFRACTION (4.3 Å)
主引用文献Structural basis of transcription: role of the trigger loop in substrate specificity and catalysis
Cell(Cambridge,Mass.), 127, 2006
2O55
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Crystal Structure of a putative glycerophosphodiester phosphodiesterase from Galdieria sulphuraria
分子名称: SULFATE ION, putative glycerophosphodiester phosphodiesterase
著者Mccoy, J.G, Wesenberg, G.E, Phillips Jr, G.N, Bitto, E, Bingman, C.A, Center for Eukaryotic Structural Genomics (CESG)
登録日2006-12-05
公開日2006-12-19
最終更新日2023-12-27
実験手法X-RAY DIFFRACTION (2.806 Å)
主引用文献Crystal Structure of a putative glycerophosphodiester phosphodiesterase from Galdieria sulphuraria
To be Published
2O6V
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Crystal structure and solution NMR studies of Lys48-linked tetraubiquitin at neutral pH
分子名称: 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, SULFATE ION, Ubiquitin
著者Eddins, M.J, Wolberger, C.
登録日2006-12-08
公開日2007-02-13
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Crystal Structure and Solution NMR Studies of Lys48-linked Tetraubiquitin at Neutral pH
J.Mol.Biol., 367, 2007
2NUP
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Crystal Structure of the human Sec23a/24a heterodimer, complexed with the SNARE protein Sec22b
分子名称: Protein transport protein Sec23A, Protein transport protein Sec24A, Vesicle-trafficking protein SEC22b, ...
著者Mancias, J.D, Goldberg, J.
登録日2006-11-09
公開日2007-05-22
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献The Transport Signal on Sec22 for Packaging into COPII-Coated Vesicles is a Conformational Epitope
Mol.Cell, 26, 2007
2O21
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Solution structure of the anti-apoptotic protein Bcl-2 in complex with an acyl-sulfonamide-based ligand
分子名称: 3-NITRO-N-{4-[2-(2-PHENYLETHYL)-1,3-BENZOTHIAZOL-5-YL]BENZOYL}-4-{[2-(PHENYLSULFANYL)ETHYL]AMINO}BENZENESULFONAMIDE, Apoptosis regulator Bcl-2
著者Bruncko, M, Oost, T.K, Belli, B.A, Ding, H, Joseph, M.K, Kunzer, A, Martineau, D, McClellan, W.J, Mitten, M, Ng, S.C, Nimmer, P.M, Oltersdorf, T, Park, C.M, Petros, A.M, Shoemaker, A.R, Song, X, Wang, X, Wendt, M.D, Zhang, H, Fesik, S.W, Rosenberg, S.H, Elmore, S.W.
登録日2006-11-29
公開日2007-02-27
最終更新日2023-12-27
実験手法SOLUTION NMR
主引用文献Studies Leading to Potent, Dual Inhibitors of Bcl-2 and Bcl-xL.
J.Med.Chem., 50, 2007
2NXN
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T. thermophilus ribosomal protein L11 methyltransferase (PrmA) in complex with ribosomal protein L11
分子名称: 50S ribosomal protein L11, Ribosomal protein L11 methyltransferase
著者Demirci, H, Gregory, S.T, Dahlberg, A.E, Jogl, G.
登録日2006-11-17
公開日2006-12-26
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Recognition of ribosomal protein L11 by the protein trimethyltransferase PrmA.
Embo J., 26, 2007
8HFQ
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BU of 8hfq by Molmil
Cryo-EM structure of CpcL-PBS from cyanobacterium Synechocystis sp. PCC 6803
分子名称: C-phycocyanin alpha subunit, C-phycocyanin beta subunit, Ferredoxin--NADP reductase, ...
著者Zheng, L, Zhang, Z, Wang, H, Zheng, Z, Gao, N, Zhao, J.
登録日2022-11-11
公開日2023-11-08
実験手法ELECTRON MICROSCOPY (2.64 Å)
主引用文献Cryo-EM and femtosecond spectroscopic studies provide mechanistic insight into the energy transfer in CpcL-phycobilisomes.
Nat Commun, 14, 2023
7NUG
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Influenza A/California/07/2009(H1N1) endonuclease in complex with orientin
分子名称: 1,2-ETHANEDIOL, 2-(2-{2-[2-(2-METHOXY-ETHOXY)-ETHOXY]-ETHOXY}-ETHOXY)-ETHANOL, DI(HYDROXYETHYL)ETHER, ...
著者Radilova, K, Brynda, J.
登録日2021-03-12
公開日2021-07-28
最終更新日2024-01-31
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Synthesis and In Vitro Evaluation of C-7 and C-8 Luteolin Derivatives as Influenza Endonuclease Inhibitors.
Int J Mol Sci, 22, 2021
2OCV
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Structural basis of Na+ activation mimicry in murine thrombin
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Thrombin
著者Marino, F, Chen, Z, Ergenekan, C.E, Bush, L.A, Mathews, F.S, Di Cera, E.
登録日2006-12-21
公開日2007-04-10
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Structural basis of na+ activation mimicry in murine thrombin.
J.Biol.Chem., 282, 2007
7NUH
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Influenza A/California/07/2009(H1N1) endonuclease with I38T mutation in complex with orientin
分子名称: 1,2-ETHANEDIOL, DI(HYDROXYETHYL)ETHER, MAGNESIUM ION, ...
著者Radilova, K, Brynda, J.
登録日2021-03-12
公開日2021-07-28
最終更新日2024-01-31
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Synthesis and In Vitro Evaluation of C-7 and C-8 Luteolin Derivatives as Influenza Endonuclease Inhibitors.
Int J Mol Sci, 22, 2021

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