4V5J
 
 | | Structure of the 70S ribosome bound to Release factor 2 and a substrate analog provides insights into catalysis of peptide release | | 分子名称: | 16S Ribosomal RNA, 23S RIBOSOMAL RNA, 30S RIBOSOMAL PROTEIN S10, ... | | 著者 | Jin, H, Kelley, A.C, Loakes, D, Ramakrishnan, V. | | 登録日 | 2010-03-24 | | 公開日 | 2014-07-09 | | 最終更新日 | 2024-11-20 | | 実験手法 | X-RAY DIFFRACTION (3.1 Å) | | 主引用文献 | Structure of the 70S ribosome bound to release factor 2 and a substrate analog provides insights into catalysis of peptide release.
Proc. Natl. Acad. Sci. U.S.A., 107, 2010
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4V64
 | | Crystal structure of the bacterial ribosome from Escherichia coli in complex with hygromycin B. | | 分子名称: | 16S ribosomal RNA, 23S ribosomal RNA, 30S ribosomal protein S10, ... | | 著者 | Borovinskaya, M.A, Shoji, S, Fredrick, K, Cate, J.H.D. | | 登録日 | 2008-06-11 | | 公開日 | 2014-07-09 | | 最終更新日 | 2023-09-20 | | 実験手法 | X-RAY DIFFRACTION (3.5 Å) | | 主引用文献 | Structural basis for hygromycin B inhibition of protein biosynthesis
Rna, 14, 2008
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4W2G
 | | Crystal structure of the Thermus thermophilus 70S ribosome in complex with pactamycin (soaked), mRNA and three deacylated tRNAs in the A, P and E sites | | 分子名称: | 16S Ribosomal RNA, 23S Ribosomal RNA, 30S Ribosomal Protein S10, ... | | 著者 | Polikanov, Y.S, Osterman, I.A, Szal, T, Tashlitsky, V.N, Serebryakova, M.V, Kusochek, P, Bulkley, D, Malanicheva, I.A, Efimenko, T.A, Efremenkova, O.V, Konevega, A.L, Shaw, K.J, Bogdanov, A.A, Rodnina, M.V, Dontsova, O.A, Mankin, A.S, Steitz, T.A, Sergiev, P.V. | | 登録日 | 2014-09-12 | | 公開日 | 2014-10-15 | | 最終更新日 | 2023-12-27 | | 実験手法 | X-RAY DIFFRACTION (2.55 Å) | | 主引用文献 | Amicoumacin a inhibits translation by stabilizing mRNA interaction with the ribosome.
Mol.Cell, 56, 2014
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4V5B
 | | Structure of PDF binding helix in complex with the ribosome. | | 分子名称: | 16S RIBOSOMAL RNA, 23S RIBOSOMAL RNA, 30S RIBOSOMAL PROTEIN S10, ... | | 著者 | Bingel-Erlenmeyer, R, Kohler, R, Kramer, G, Sandikci, A, Antolic, S, Maier, T, Schaffitzel, C, Wiedmann, B, Bukau, B, Ban, N. | | 登録日 | 2007-11-22 | | 公開日 | 2014-07-09 | | 最終更新日 | 2024-11-13 | | 実験手法 | X-RAY DIFFRACTION (3.74 Å) | | 主引用文献 | A Peptide Deformylase-Ribosome Complex Reveals Mechanism of Nascent Chain Processing.
Nature, 452, 2008
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4CNI
 | | Crystal structure of the Fab portion of Olokizumab in complex with IL- 6 | | 分子名称: | INTERLEUKIN-6, OLOKIZUMAB HEAVY CHAIN, FAB PORTION, ... | | 著者 | Shaw, S, Bourne, T, Meier, C, Carrington, B, Gelinas, R, Henry, A, Popplewell, A, Adams, R, Baker, T, Rapecki, S, Marshall, D, Neale, H, Lawson, A. | | 登録日 | 2014-01-22 | | 公開日 | 2014-04-30 | | 最終更新日 | 2024-10-23 | | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | | 主引用文献 | Discovery and Characterization of Olokizumab: A Humanized Antibody Targeting Interleukin-6 and Neutralizing Gp130-Signaling.
Mabs, 6, 2014
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7SO0
 | | Crystal Structure of the Engineered Tick Evasin EVA-P974(F31A) Complexed to Human Chemokine CCL2 | | 分子名称: | C-C motif chemokine 2, Evasin P974 | | 著者 | Bhusal, R.P, Devkota, S.R, Aryal, P, Wilce, M.C.J, Stone, M.J. | | 登録日 | 2021-10-28 | | 公開日 | 2022-03-16 | | 最終更新日 | 2024-10-23 | | 実験手法 | X-RAY DIFFRACTION (1.74 Å) | | 主引用文献 | Structure-guided engineering of tick evasins for targeting chemokines in inflammatory diseases.
Proc.Natl.Acad.Sci.USA, 119, 2022
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5OOB
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7Q3N
 | | Cryo-EM of the complex between human uromodulin (UMOD)/Tamm-Horsfall protein (THP) and the FimH lectin domain from uropathogenic E. coli | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, Type 1 fimbiral adhesin FimH, ... | | 著者 | Jovine, L, Xu, C, Stsiapanava, A, Carroni, M, Tunyasuvunakool, K, Jumper, J, Wu, B. | | 登録日 | 2021-10-28 | | 公開日 | 2022-03-16 | | 最終更新日 | 2024-10-23 | | 実験手法 | ELECTRON MICROSCOPY (7.4 Å) | | 主引用文献 | Structure of the decoy module of human glycoprotein 2 and uromodulin and its interaction with bacterial adhesin FimH.
Nat.Struct.Mol.Biol., 29, 2022
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5N2S
 | | Crystal structure of stabilized A1 receptor in complex with PSB36 at 3.3A resolution | | 分子名称: | 1-butyl-3-(3-oxidanylpropyl)-8-[(1~{R},5~{S})-3-tricyclo[3.3.1.0^{3,7}]nonanyl]-7~{H}-purine-2,6-dione, SULFATE ION, Soluble cytochrome b562,Adenosine receptor A1 | | 著者 | Cheng, R.K.Y, Segala, E, Robertson, N, Deflorian, F, Dore, A.S, Errey, J.C, Fiez-Vandal, C, Marshall, F.H, Cooke, R.M. | | 登録日 | 2017-02-08 | | 公開日 | 2017-07-26 | | 最終更新日 | 2024-11-13 | | 実験手法 | X-RAY DIFFRACTION (3.303 Å) | | 主引用文献 | Structures of Human A1 and A2A Adenosine Receptors with Xanthines Reveal Determinants of Selectivity.
Structure, 25, 2017
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7SCU
 | | Crystal Structure of the Tick Evasin EVA-AAM1001 Complexed to Human Chemokine CCL7 | | 分子名称: | C-C motif chemokine 7, Evasin P1243 | | 著者 | Devkota, S.R, Bhusal, R.P, Aryal, P, Wilce, M.C.J, Stone, M.J. | | 登録日 | 2021-09-29 | | 公開日 | 2023-04-05 | | 最終更新日 | 2024-10-16 | | 実験手法 | X-RAY DIFFRACTION (1.86 Å) | | 主引用文献 | Crystal Structure of Tick Evasin EVA-AAM1001 complexed to human chemokine CCL7
To Be Published
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5EY3
 | | X-ray structure of the thymidine phosphorylase from Salmonella typhimurium in complex with cytidine and sulphate | | 分子名称: | 1,2-ETHANEDIOL, 4-AMINO-1-BETA-D-RIBOFURANOSYL-2(1H)-PYRIMIDINONE, GLYCEROL, ... | | 著者 | Balaev, V.V, Lashkov, A.A, Gabdulkhakov, A.G, Betzel, C, Mikhailov, A.M. | | 登録日 | 2015-11-24 | | 公開日 | 2016-12-07 | | 最終更新日 | 2024-01-10 | | 実験手法 | X-RAY DIFFRACTION (1.905 Å) | | 主引用文献 | X-ray structure of the thymidine phosphorylase from Salmonella typhimurium in complex with cytidine and sulphate
To Be Published
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5OO6
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8EQV
 | | Cryo-EM structure of PRC2 in complex with the long isoform of AEBP2 | | 分子名称: | Histone-binding protein RBBP4, Histone-lysine N-methyltransferase EZH2, Polycomb protein EED, ... | | 著者 | Boudes, M, Zhang, Q, Flanigan, S.F, Davidovich, C. | | 登録日 | 2022-10-09 | | 公開日 | 2024-07-31 | | 最終更新日 | 2025-06-04 | | 実験手法 | ELECTRON MICROSCOPY (3.64 Å) | | 主引用文献 | To be updated
To Be Published
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7SZK
 | | Cryo-EM structure of 27a bound to E. coli RNAP and rrnBP1 promoter complex | | 分子名称: | (2S,7R,7aR,13aP,16Z,18E,20S,21S,22R,23R,24R,25S,26R,27S,28E)-5,21,23-trihydroxy-27-methoxy-2,4,16,20,22,24,26-heptamethyl-10-[4-(2-methylpropyl)piperazin-1-yl]-12-({4-[(morpholin-4-yl)methyl]phenyl}methoxy)-1,6,15-trioxo-1,2,7,7a-tetrahydro-6H-2,7-(epoxypentadeca[1,11,13]trienoimino)[1]benzofuro[4,5-a]phenoxazin-25-yl acetate, DNA (5'-D(P*CP*TP*CP*GP*TP*AP*GP*AP*GP*TP*CP*CP*GP*TP*GP*TP*CP*A)-3'), DNA-directed RNA polymerase subunit alpha, ... | | 著者 | Shin, Y, Murakami, K.S. | | 登録日 | 2021-11-28 | | 公開日 | 2022-07-13 | | 最終更新日 | 2024-02-28 | | 実験手法 | ELECTRON MICROSCOPY (2.94 Å) | | 主引用文献 | Optimization of Benzoxazinorifamycins to Improve Mycobacterium tuberculosis RNA Polymerase Inhibition and Treatment of Tuberculosis.
Acs Infect Dis., 8, 2022
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7SZJ
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8FJ0
 | | Crystal Structure of the Tick Evasin EVA-AAM1001(Y44A) Complexed to Human Chemokine CCL2 | | 分子名称: | C-C motif chemokine 2, Evasin P1243 | | 著者 | Devkota, S.R, Bhusal, R.P, Aryal, P, Wilce, M.C.J, Stone, M.J. | | 登録日 | 2022-12-18 | | 公開日 | 2023-03-29 | | 最終更新日 | 2024-10-16 | | 実験手法 | X-RAY DIFFRACTION (2.91 Å) | | 主引用文献 | Engineering broad-spectrum inhibitors of inflammatory chemokines from subclass A3 tick evasins.
Nat Commun, 14, 2023
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2K0A
 | | 1H, 15N and 13C chemical shift assignments for Rds3 protein | | 分子名称: | Pre-mRNA-splicing factor RDS3, ZINC ION | | 著者 | Loening, N, van Roon, A, Yang, J, Nagai, K, Neuhaus, D. | | 登録日 | 2008-01-31 | | 公開日 | 2008-07-22 | | 最終更新日 | 2024-05-29 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Solution structure of the U2 snRNP protein Rds3p reveals a knotted zinc-finger motif.
Proc.Natl.Acad.Sci.Usa, 105, 2008
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8FK8
 | | Crystal Structure of the Tick Evasin EVA-AAM1001(L39P) Complexed to Human Chemokine CCL7 | | 分子名称: | C-C motif chemokine 7, Evasin P1243 | | 著者 | Devkota, S.R, Bhusal, R.P, Aryal, P, Wilce, M.C.J, Stone, M.J. | | 登録日 | 2022-12-20 | | 公開日 | 2023-03-29 | | 最終更新日 | 2024-10-23 | | 実験手法 | X-RAY DIFFRACTION (1.96 Å) | | 主引用文献 | Engineering broad-spectrum inhibitors of inflammatory chemokines from subclass A3 tick evasins.
Nat Commun, 14, 2023
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8FK6
 | | Crystal Structure of the Tick Evasin EVA-AAM1001(Y44A) Complexed to Human Chemokine CCL7 | | 分子名称: | C-C motif chemokine 7, Evasin P1243 | | 著者 | Devkota, S.R, Bhusal, R.P, Aryal, P, Wilce, M.C.J, Stone, M.J. | | 登録日 | 2022-12-20 | | 公開日 | 2023-03-29 | | 最終更新日 | 2024-11-06 | | 実験手法 | X-RAY DIFFRACTION (1.74 Å) | | 主引用文献 | Engineering broad-spectrum inhibitors of inflammatory chemokines from subclass A3 tick evasins.
Nat Commun, 14, 2023
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8FJ3
 | | Crystal Structure of the Tick Evasin EVA-AAM1001 Complexed to Human Chemokine CCL7(Y13A) | | 分子名称: | C-C motif chemokine 7, Evasin P1243 | | 著者 | Devkota, S.R, Bhusal, R.P, Aryal, P, Wilce, M.C.J, Stone, M.J. | | 登録日 | 2022-12-19 | | 公開日 | 2023-03-29 | | 最終更新日 | 2024-10-30 | | 実験手法 | X-RAY DIFFRACTION (2.07 Å) | | 主引用文献 | Engineering broad-spectrum inhibitors of inflammatory chemokines from subclass A3 tick evasins.
Nat Commun, 14, 2023
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7S58
 | | Crystal Structure of the tick evasin EVA-P974 complexed to human chemokine CCL7 | | 分子名称: | C-C motif chemokine 7, Evasin P974 | | 著者 | Bhusal, R.P, Devkota, S.R, Aryal, P, Wilce, M.C.J, Stone, M.J. | | 登録日 | 2021-09-10 | | 公開日 | 2022-03-16 | | 最終更新日 | 2024-10-23 | | 実験手法 | X-RAY DIFFRACTION (1.82 Å) | | 主引用文献 | Structure-guided engineering of tick evasins for targeting chemokines in inflammatory diseases.
Proc.Natl.Acad.Sci.USA, 119, 2022
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1KJM
 | | TAP-A-associated rat MHC class I molecule | | 分子名称: | B6 Peptide, RT1 class I histocompatibility antigen, AA alpha chain, ... | | 著者 | Rudolph, M.G, Stevens, J, Speir, J.A, Trowsdale, J, Butcher, G.W, Joly, E, Wilson, I.A. | | 登録日 | 2001-12-04 | | 公開日 | 2002-12-18 | | 最終更新日 | 2024-11-20 | | 実験手法 | X-RAY DIFFRACTION (2.35 Å) | | 主引用文献 | Crystal structures of two rat MHC class Ia (RT1-A) molecules that are associated differentially
with peptide transporter alleles TAP-A and TAP-B.
J.Mol.Biol., 324, 2002
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1KPU
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4LCY
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1KO5
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