7SO0
Crystal Structure of the Engineered Tick Evasin EVA-P974(F31A) Complexed to Human Chemokine CCL2
Summary for 7SO0
Entry DOI | 10.2210/pdb7so0/pdb |
Descriptor | Evasin P974, C-C motif chemokine 2 (3 entities in total) |
Functional Keywords | inflammation, chemokine, tick evasin, immune system |
Biological source | Amblyomma cajennense (Cayenne tick, Acarus cajennensis) More |
Total number of polymer chains | 2 |
Total formula weight | 18298.99 |
Authors | Bhusal, R.P.,Devkota, S.R.,Aryal, P.,Wilce, M.C.J.,Stone, M.J. (deposition date: 2021-10-28, release date: 2022-03-16, Last modification date: 2023-10-18) |
Primary citation | Bhusal, R.P.,Aryal, P.,Devkota, S.R.,Pokhrel, R.,Gunzburg, M.J.,Foster, S.R.,Lim, H.D.,Payne, R.J.,Wilce, M.C.J.,Stone, M.J. Structure-guided engineering of tick evasins for targeting chemokines in inflammatory diseases. Proc.Natl.Acad.Sci.USA, 119:-, 2022 Cited by PubMed: 35217625DOI: 10.1073/pnas.2122105119 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.74 Å) |
Structure validation
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