7SO0
Crystal Structure of the Engineered Tick Evasin EVA-P974(F31A) Complexed to Human Chemokine CCL2
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Evasin P974 | polymer | 85 | 9626.0 | 1 | UniProt (A0A023FDY8) Pfam (PF19429) | Amblyomma cajennense (Cayenne tick Acarus cajennensis) | |
| 2 | B (B) | C-C motif chemokine 2 | polymer | 76 | 8673.0 | 1 | UniProt (P13500) Pfam (PF00048) | Homo sapiens (Human) | HC11,Monocyte chemoattractant protein 1,Monocyte chemotactic and activating factor,MCAF,Monocyte chemotactic protein 1,MCP-1,Monocyte secretory protein JE,Small-inducible cytokine A2 |
| 3 | C, D (A, B) | water | water | 18.0 | 129 | Chemie (HOH) |
Sequence modifications
A: 1 - 85 (UniProt: A0A023FDY8)
B: 1 - 76 (UniProt: P13500)
| PDB | External Database | Details |
|---|---|---|
| Ala 23 | Phe 52 | engineered mutation |
| PDB | External Database | Details |
|---|---|---|
| Ala 8 | Pro 31 | conflict |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 18299.0 | |
| All* | Total formula weight | 18299.0 |
