PDB: 10243 件ウェブページステータス検索Chemie searchBIRD

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4BJJ	Sfc1-Sfc7 dimerization module 分子名称: MERCURY (II) ION, TRANSCRIPTION FACTOR TAU SUBUNIT SFC1, TRANSCRIPTION FACTOR TAU SUBUNIT SFC7 著者 Taylor, N.M.I, Baudin, F, von Scheven, G, Muller, C.W. 登録日 2013-04-18 公開日 2013-07-31 最終更新日 2024-05-08 実験手法 X-RAY DIFFRACTION (2.4 Å) 主引用文献 RNA Polymerase III-Specific General Transcription Factor Iiic Contains a Heterodimer Resembling Tfiif RAP30/RAP74. Nucleic Acids Res., 41, 2013
2F88	Solution NMR structure of domain 5 from the Pyaiella littoralis (PL) group II intron 分子名称: D5-PL RNA RIBOZYME DOMAIN 著者 Dayie, K.T. 登録日 2005-12-02 公開日 2006-02-28 最終更新日 2024-05-29 実験手法 SOLUTION NMR 主引用文献 Structure of a self-splicing group II intron catalytic effector domain 5: parallels with spliceosomal U6 RNA Rna, 12, 2006
2A0C	Human CDK2 in complex with olomoucine II, a novel 2,6,9-trisubstituted purine cyclin-dependent kinase inhibitor 分子名称: 2-{[(2-{[(1R)-1-(HYDROXYMETHYL)PROPYL]AMINO}-9-ISOPROPYL-9H-PURIN-6-YL)AMINO]METHYL}PHENOL, Cell division protein kinase 2 著者 Krystof, V, McNae, I.W, Walkinshaw, M.D, Fischer, P.M, Muller, P, Vojtesek, B, Orsag, M, Havlicek, L, Strnad, M. 登録日 2005-06-16 公開日 2006-01-24 最終更新日 2024-03-13 実験手法 X-RAY DIFFRACTION (1.95 Å) 主引用文献 Antiproliferative activity of olomoucine II, a novel 2,6,9-trisubstituted purine cyclin-dependent kinase inhibitor Cell.Mol.Life Sci., 62, 2005
8RNA	Influenza B polymerase apo-trimer 分子名称: Acidic leucine-rich nuclear phosphoprotein 32 family member A, Polymerase acidic protein, Polymerase basic protein 2, ... 著者 Arragain, B, Cusack, S. 登録日 2024-01-09 公開日 2024-09-11 実験手法 ELECTRON MICROSCOPY (3.57 Å) 主引用文献 Structures of influenza A and B replication complexes give insight into avian to human host adaptation and reveal a role of ANP32 as an electrostatic chaperone for the apo-polymerase. Nat Commun, 15, 2024
7ZPM	Influenza A/H7N9 polymerase apo-protein dimer complex 分子名称: Polymerase acidic protein, Polymerase basic protein 2, RNA-directed RNA polymerase catalytic subunit 著者 Cusack, S, Kouba, T. 登録日 2022-04-27 公開日 2022-12-28 最終更新日 2025-07-02 実験手法 ELECTRON MICROSCOPY (2.81 Å) 主引用文献 Direct observation of backtracking by influenza A and B polymerases upon consecutive incorporation of the nucleoside analog T1106. Cell Rep, 42, 2023
8W8N	Thermus thermophilus initiation transcription complex in the pre-translocated state 分子名称: DNA (21-MER), DNA (27-MER), DNA-directed RNA polymerase subunit alpha, ... 著者 Li, L, Zhang, Y. 登録日 2023-09-04 公開日 2024-07-24 実験手法 X-RAY DIFFRACTION (2.693 Å) 主引用文献 Nanopore tweezers show fractional-nucleotide translocation in sequence-dependent pausing by RNA polymerase. Proc.Natl.Acad.Sci.USA, 121, 2024
8W8P	Thermus thermophilus initiation transcription complex containing CMPcPP in the post-translocated state 分子名称: 5'-O-[(S)-hydroxy{[(S)-hydroxy(phosphonooxy)phosphoryl]methyl}phosphoryl]cytidine, DNA (21-MER), DNA (27-MER), ... 著者 Li, L, Zhang, Y. 登録日 2023-09-04 公開日 2024-07-24 実験手法 X-RAY DIFFRACTION (3.165 Å) 主引用文献 Nanopore tweezers show fractional-nucleotide translocation in sequence-dependent pausing by RNA polymerase. Proc.Natl.Acad.Sci.USA, 121, 2024
8W8O	Thermus thermophilus initiation complex in the half-translocated state 分子名称: DNA (21-MER), DNA (27-MER), DNA-directed RNA polymerase subunit alpha, ... 著者 Li, L, Zhang, Y. 登録日 2023-09-04 公開日 2024-07-24 実験手法 X-RAY DIFFRACTION (2.512 Å) 主引用文献 Nanopore tweezers show fractional-nucleotide translocation in sequence-dependent pausing by RNA polymerase. Proc.Natl.Acad.Sci.USA, 121, 2024
8H69	Cryo-EM structure of influenza RNA polymerase 分子名称: Polymerase acidic protein, Polymerase basic protein 2, RNA (5'-R(*UP*AP*AP*AP*CP*UP*CP*CP*UP*GP*CP*UP*UP*UP*UP*GP*CP*U)-3'), ... 著者 Li, H, Wu, Y, Liang, H, Liu, Y. 登録日 2022-10-16 公開日 2023-06-28 最終更新日 2023-11-15 実験手法 ELECTRON MICROSCOPY (3.7 Å) 主引用文献 An intermediate state allows influenza polymerase to switch smoothly between transcription and replication cycles. Nat.Struct.Mol.Biol., 30, 2023
2E9T	Foot-and-mouth disease virus RNA-polymerase RNA dependent in complex with a template-primer RNA and 5F-UTP 分子名称: 5'-R(*GP*GP*GP*CP*CP*CP*(5FU))-3', 5'-R(P*UP*AP*GP*GP*GP*CP*CP*C)-3', MAGNESIUM ION, ... 著者 Ferrer-Orta, C, Arias, A, Perez-Luque, R, Escarmis, C, Domingo, E, Verdaguer, N. 登録日 2007-01-26 公開日 2007-06-26 最終更新日 2023-10-25 実験手法 X-RAY DIFFRACTION (2.6 Å) 主引用文献 Sequential structures provide insights into the fidelity of RNA replication Proc.Natl.Acad.Sci.Usa, 104, 2007
7ZGR	Polymerase module of yeast CPF in complex with Mpe1, the yPIM of Cft2 and the pre-cleaved CYC1 RNA 分子名称: Cleavage factor two protein 2, MPE1 isoform 1, Polyadenylation factor subunit 2, ... 著者 Rodriguez-Molina, J.B, Passmore, L.A. 登録日 2022-04-04 公開日 2022-05-25 最終更新日 2024-07-24 実験手法 ELECTRON MICROSCOPY (2.6 Å) 主引用文献 Mpe1 senses the binding of pre-mRNA and controls 3' end processing by CPF. Mol.Cell, 82, 2022
7ZGP	Polymerase module of CPF in complex with Mpe1 and a pre-cleaved CYC1 RNA 分子名称: MPE1 isoform 1, Polyadenylation factor subunit 2, Protein CFT1, ... 著者 Rodriguez-Molina, J.B, Passmore, L.A. 登録日 2022-04-04 公開日 2022-05-25 最終更新日 2024-07-24 実験手法 ELECTRON MICROSCOPY (2.7 Å) 主引用文献 Mpe1 senses the binding of pre-mRNA and controls 3' end processing by CPF. Mol.Cell, 82, 2022
7ZGQ	Polymerase module of yeast CPF in complex with the yPIM of Cft2 分子名称: Cleavage factor two protein 2, Polyadenylation factor subunit 2, Protein CFT1, ... 著者 Rodriguez-Molina, J.B, Passmore, L.A. 登録日 2022-04-04 公開日 2022-05-25 最終更新日 2024-07-24 実験手法 ELECTRON MICROSCOPY (2.8 Å) 主引用文献 Mpe1 senses the binding of pre-mRNA and controls 3' end processing by CPF. Mol.Cell, 82, 2022
8FFZ	TFIIIA-TFIIIC-Brf1-TBP complex bound to 5S rRNA gene 分子名称: DNA (151-MER), Transcription factor IIIA, Transcription factor IIIB 70 kDa subunit,TATA-box-binding protein, ... 著者 Talyzina, A, He, Y. 登録日 2022-12-11 公開日 2023-06-21 最終更新日 2023-08-16 実験手法 ELECTRON MICROSCOPY (3.8 Å) 主引用文献 Structural basis of TFIIIC-dependent RNA polymerase III transcription initiation. Mol.Cell, 83, 2023
6QI9	Truncated human R2TP complex, structure 4 (ADP-empty) 分子名称: ADENOSINE-5'-DIPHOSPHATE, RuvB-like 1, RuvB-like 2 著者 Munoz-Hernandez, H, Rodriguez, C.F, Llorca, O. 登録日 2019-01-18 公開日 2019-05-15 最終更新日 2024-05-15 実験手法 ELECTRON MICROSCOPY (4.63 Å) 主引用文献 Structural mechanism for regulation of the AAA-ATPases RUVBL1-RUVBL2 in the R2TP co-chaperone revealed by cryo-EM. Sci Adv, 5, 2019
6QI8	Truncated human R2TP complex, structure 3 (ADP-filled) 分子名称: ADENOSINE-5'-DIPHOSPHATE, RuvB-like 1, RuvB-like 2 著者 Munoz-Hernandez, H, Rodriguez, C.F, Llorca, O. 登録日 2019-01-18 公開日 2019-04-10 最終更新日 2024-05-15 実験手法 ELECTRON MICROSCOPY (3.75 Å) 主引用文献 Structural mechanism for regulation of the AAA-ATPases RUVBL1-RUVBL2 in the R2TP co-chaperone revealed by cryo-EM. Sci Adv, 5, 2019
2M4V	Mycobacterium tuberculosis RNA polymerase binding protein A (RbpA) and its interactions with sigma factors 分子名称: Putative uncharacterized protein 著者 Bortoluzzi, A, Muskett, F.W, Waters, L.C, Addis, P.W, Rieck, B, Munder, T, Schleier, S, Forti, F, Ghisotti, D, Carr, M.D, O'Hare, H.M. 登録日 2013-02-11 公開日 2013-04-17 最終更新日 2024-05-15 実験手法 SOLUTION NMR 主引用文献 Mycobacterium tuberculosis RNA polymerase-binding protein A (RbpA) and its interactions with sigma factors. J.Biol.Chem., 288, 2013
4IKA	Crystal structure of EV71 3Dpol-VPg 分子名称: 3Dpol, NICKEL (II) ION, VPg 著者 Chen, C, Wang, Y.X, Lou, Z.Y. 登録日 2012-12-25 公開日 2013-09-04 最終更新日 2023-11-08 実験手法 X-RAY DIFFRACTION (2.7 Å) 主引用文献 Crystal structure of enterovirus 71 RNA-dependent RNA polymerase complexed with its protein primer VPg: implication for a trans mechanism of VPg uridylylation J.Virol., 87, 2013
5FKV	cryo-EM structure of the E. coli replicative DNA polymerase complex bound to DNA (DNA polymerase III alpha, beta, epsilon, tau complex) 分子名称: DNA POLYMERASE III BETA, DNA POLYMERASE III EPSILON, DNA POLYMERASE III SUBUNIT ALPHA, ... 著者 Fernandez-Leiro, R, Conrad, J, Scheres, S.H.W, Lamers, M.H. 登録日 2015-10-20 公開日 2015-11-25 最終更新日 2024-05-08 実験手法 ELECTRON MICROSCOPY (8.04 Å) 主引用文献 cryo-EM structures of theE. colireplicative DNA polymerase reveal its dynamic interactions with the DNA sliding clamp, exonuclease andtau. Elife, 4, 2015
8A3Y	Structure of mammalian Pol II-DSIF-SPT6-PAF1-TFIIS-hexasome elongation complex 分子名称: DNA-directed RNA polymerase II subunit E, DNA-directed RNA polymerase II subunit RPB11-a, DNA-directed RNA polymerase II subunit RPB3, ... 著者 Farnung, L, Ochmann, M, Garg, G, Vos, S.M, Cramer, P. 登録日 2022-06-09 公開日 2024-07-31 最終更新日 2024-11-06 実験手法 ELECTRON MICROSCOPY (3.3 Å) 主引用文献 Structure of a backtracked hexasomal intermediate of nucleosome transcription. Mol.Cell, 82, 2022
8A40	Structure of mammalian Pol II-TFIIS elongation complex 分子名称: DNA-directed RNA polymerase II subunit E, DNA-directed RNA polymerase II subunit RPB11-a, DNA-directed RNA polymerase II subunit RPB3, ... 著者 Farnung, L, Ochmann, M, Garg, G, Vos, S.M, Cramer, P. 登録日 2022-06-09 公開日 2023-08-23 最終更新日 2024-11-13 実験手法 ELECTRON MICROSCOPY (3 Å) 主引用文献 Structure of a backtracked hexasomal intermediate of nucleosome transcription. Mol.Cell, 82, 2022
8BE0	Early transcription elongation state of influenza B/Mem polymerase backtracked due to double incoproation of nucleotide analogue T1106 and with singly incoporated T1106 at the C +1 position 分子名称: 3' vRNA, 5' vRNA, MAGNESIUM ION, ... 著者 Cusack, S, Kouba, T. 登録日 2022-10-20 公開日 2022-12-28 最終更新日 2025-07-09 実験手法 ELECTRON MICROSCOPY (2.34 Å) 主引用文献 Direct observation of backtracking by influenza A and B polymerases upon consecutive incorporation of the nucleoside analog T1106. Cell Rep, 42, 2023
8BEK	Early transcription elongation state of influenza A/H7N9 backtracked polymerase with singly incoporated T1106 at the U +1 position 分子名称: 3' vRNA, 5' vRNA, MAGNESIUM ION, ... 著者 Cusack, S, Kouba, T. 登録日 2022-10-21 公開日 2022-12-28 最終更新日 2025-07-02 実験手法 ELECTRON MICROSCOPY (2.86 Å) 主引用文献 Direct observation of backtracking by influenza A and B polymerases upon consecutive incorporation of the nucleoside analog T1106. Cell Rep, 42, 2023
8BF5	Early transcription elongation state of influenza A/H7N9 polymerase stalled with incoming GTP analogue 分子名称: 3' vRNA, 5' vRNA, MAGNESIUM ION, ... 著者 Cusack, S, Kouba, T. 登録日 2022-10-24 公開日 2022-12-28 最終更新日 2025-07-09 実験手法 ELECTRON MICROSCOPY (2.96 Å) 主引用文献 Direct observation of backtracking by influenza A and B polymerases upon consecutive incorporation of the nucleoside analog T1106. Cell Rep, 42, 2023
8BDR	Early transcription elongation state of influenza B/Mem polymerase backtracked due to double incoproation of nucleotide analogue T1106 and with singly incoporated T1106 at the U +1 position 分子名称: 3' vRNA, 5' vRNA, MAGNESIUM ION, ... 著者 Cusack, S, Kouba, T. 登録日 2022-10-19 公開日 2022-12-28 最終更新日 2025-07-02 実験手法 ELECTRON MICROSCOPY (2.7 Å) 主引用文献 Direct observation of backtracking by influenza A and B polymerases upon consecutive incorporation of the nucleoside analog T1106. Cell Rep, 42, 2023

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