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2LEC
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Solution structure of human SRSF2 (SC35) RRM in complex with 5'-UGGAGU-3'
分子名称: RNA (5'-R(*UP*GP*GP*AP*GP*U)-3'), Serine/arginine-rich splicing factor 2
著者Daubner, G.M, Clery, A, Jayne, S, Stevenin, J, Allain, F.H.-T.
登録日2011-06-15
公開日2011-11-23
最終更新日2024-05-08
実験手法SOLUTION NMR
主引用文献A syn-anti conformational difference allows SRSF2 to recognize guanines and cytosines equally well.
Embo J., 31, 2012
3KGP
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BU of 3kgp by Molmil
Crystal Structures of Urokinase-type Plasminogen Activator in Complex with 4-(Aminomethyl) Benzoic Acid and 4-(Aminomethyl-phenyl)-methanol
分子名称: 4-(aminomethyl)benzoic acid, SULFATE ION, Urokinase-type plasminogen activator
著者Jiang, L.-G, Zhao, G.-X, Bian, X.-B, Yuan, C, Huang, Z.-X, Huang, M.-D.
登録日2009-10-29
公開日2009-12-01
最終更新日2023-11-01
実験手法X-RAY DIFFRACTION (2.35 Å)
主引用文献Crystal Structures of Urokinase-type Plasminogen Activator in Complex with 4-(Aminomethyl) Benzoic Acid and 4-(Aminomethyl-phenyl)-methanol
CHIN.J.STRUCT.CHEM., 28, 2009
7CFW
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BU of 7cfw by Molmil
Crystal structure of the receiver domain of sensor histidine kinase PA1611 (PA1611REC) from Pseudomonas aeruginosa PAO1 with calcium ion coordinated in the active site cleft
分子名称: CALCIUM ION, Histidine kinase
著者Chen, S.K, Guan, H.H, Wu, P.H, Lin, L.T, Wu, M.C, Chang, H.Y, Chen, N.C, Lin, C.C, Chuankhayan, P, Huang, Y.C, Lin, P.J, Chen, C.J.
登録日2020-06-29
公開日2020-11-04
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (1.31 Å)
主引用文献Structural insights into the histidine-containing phospho-transfer protein and receiver domain of sensor histidine kinase suggest a complex model in the two-component regulatory system in Pseudomonas aeruginosa
Iucrj, 7, 2020
7CCU
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BU of 7ccu by Molmil
Crystal structure of death-associated protein kinase 1 in complex with resveratrol
分子名称: Death-associated protein kinase 1, RESVERATROL, SULFATE ION
著者Yokoyama, T, Suzuki, R, Mizuguchi, M.
登録日2020-06-18
公開日2021-01-20
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (1.649 Å)
主引用文献Crystal structure of death-associated protein kinase 1 in complex with the dietary compound resveratrol.
Iucrj, 8, 2020
2L4D
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BU of 2l4d by Molmil
cytochrome c domain of pp3183 protein from Pseudomonas putida
分子名称: HEME C, SCO1/SenC family protein/cytochrome c
著者Banci, L, Bertini, I, Ciofi-Baffoni, S, Kozyreva, T, Mori, M, Wang, S.
登録日2010-10-04
公開日2011-01-26
最終更新日2011-07-13
実験手法SOLUTION NMR
主引用文献Sco proteins are involved in electron transfer processes
J.Biol.Inorg.Chem., 16, 2011
3KX5
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BU of 3kx5 by Molmil
Crystal structure of Bacillus megaterium BM3 heme domain mutant F261E
分子名称: Bifunctional P-450/NADPH-P450 reductase, PROTOPORPHYRIN IX CONTAINING FE, SULFATE ION
著者Girvan, H.M, Levy, C.W, Leys, D, Munro, A.W.
登録日2009-12-02
公開日2010-05-19
最終更新日2024-05-29
実験手法X-RAY DIFFRACTION (1.686 Å)
主引用文献Glutamate-haem ester bond formation is disfavoured in flavocytochrome P450 BM3: characterization of glutamate substitution mutants at the haem site of P450 BM3.
Biochem.J., 427, 2010
3KK9
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BU of 3kk9 by Molmil
CaMKII Substrate Complex B
分子名称: Calcium/calmodulin dependent protein kinase II
著者Kuriyan, J, Chao, L.H, Pellicena, P, Deindl, S, Barclay, L.A, Schulman, H.
登録日2009-11-04
公開日2010-02-09
最終更新日2021-10-13
実験手法X-RAY DIFFRACTION (3.206 Å)
主引用文献Intersubunit capture of regulatory segments is a component of cooperative CaMKII activation.
Nat.Struct.Mol.Biol., 17, 2010
2LD5
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BU of 2ld5 by Molmil
Solution NMR-derived complex structure of Hoxa13 DNA binding domain bound to DNA
分子名称: DNA (5'-D(*CP*AP*AP*AP*TP*AP*AP*AP*AP*TP*C)-3'), DNA (5'-D(P*GP*AP*TP*TP*TP*TP*AP*TP*TP*TP*G)-3'), Homeobox protein Hox-A13
著者Zhang, Y.
登録日2011-05-14
公開日2011-08-10
最終更新日2024-05-01
実験手法SOLUTION NMR
主引用文献Structural basis for sequence specific DNA binding and protein dimerization of HOXA13.
Plos One, 6, 2011
3KN6
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Crystal structure of the C-terminal kinase domain of MSK1
分子名称: Ribosomal protein S6 kinase alpha-5
著者D'Angelo, I, Malakhova, M, Dong, Z.
登録日2009-11-12
公開日2010-04-21
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献The crystal structure of the active form of the C-terminal kinase domain of mitogen- and stress-activated protein kinase 1.
J.Mol.Biol., 399, 2010
2LH1
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BU of 2lh1 by Molmil
X-RAY STRUCTURAL INVESTIGATION OF LEGHEMOGLOBIN. VI. STRUCTURE OF ACETATE-FERRILEGHEMOGLOBIN AT A RESOLUTION OF 2.0 ANGSTROMS (RUSSIAN)
分子名称: ACETATE ION, LEGHEMOGLOBIN (ACETO MET), PROTOPORPHYRIN IX CONTAINING FE
著者Vainshtein, B.K, Harutyunyan, E.H, Kuranova, I.P, Borisov, V.V, Sosfenov, N.I, Pavlovsky, A.G, Grebenko, A.I, Konareva, N.V.
登録日1982-04-23
公開日1983-01-20
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献X-Ray Structural Investigation of Leghemoglobin. Vi. Structure of Acetate-Ferrileghemoglobin at a Resolution of 2.0 Angstroms (Russian)
Kristallografiya, 25, 1980
3L38
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BU of 3l38 by Molmil
Bace1 in complex with the aminopyridine Compound 44
分子名称: 6-({2-(2-chlorophenyl)-5-[4-(pyrimidin-5-yloxy)phenyl]-1H-pyrrol-1-yl}methyl)pyridin-2-amine, Beta-secretase 1
著者Olland, A.M, Chopra, R.
登録日2009-12-16
公開日2010-04-28
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Novel pyrrolyl 2-aminopyridines as potent and selective human beta-secretase (BACE1) inhibitors.
Bioorg.Med.Chem.Lett., 20, 2010
2L9R
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BU of 2l9r by Molmil
Solution NMR Structure of Homeobox domain of Homeobox protein Nkx-3.1 from homo sapiens, Northeast Structural Genomics Consortium Target HR6470A
分子名称: Homeobox protein Nkx-3.1
著者Liu, G, Xiao, R, Lee, H.-W, Hamilton, K, Ciccosanti, C, Wang, H.B, Acton, T.B, Everett, J.K, Huang, Y.J, Montelione, G.T, Northeast Structural Genomics Consortium (NESG)
登録日2011-02-22
公開日2011-04-20
最終更新日2024-05-15
実験手法SOLUTION NMR
主引用文献Solution NMR Structure of Homeobox domain of Homeobox protein Nkx-3.1 from homo sapiens, Northeast Structural Genomics Consortium Target HR6470A
To be Published
2LH5
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BU of 2lh5 by Molmil
X-RAY STRUCTURAL INVESTIGATION OF LEGHEMOGLOBIN. VI. STRUCTURE OF ACETATE-FERRILEGHEMOGLOBIN AT A RESOLUTION OF 2.0 ANGSTROMS (RUSSIAN)
分子名称: FLUORIDE ION, LEGHEMOGLOBIN (FLUORO MET), PROTOPORPHYRIN IX CONTAINING FE
著者Vainshtein, B.K, Harutyunyan, E.H, Kuranova, I.P, Borisov, V.V, Sosfenov, N.I, Pavlovsky, A.G, Grebenko, A.I, Konareva, N.V.
登録日1982-04-23
公開日1983-01-20
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献X-Ray Structural Investigation of Leghemoglobin. Vi. Structure of Acetate-Ferrileghemoglobin at a Resolution of 2.0 Angstroms (Russian)
Kristallografiya, 25, 1980
2LA4
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BU of 2la4 by Molmil
NMR structure of the C-terminal RRM domain of poly(U) binding 1
分子名称: Nuclear and cytoplasmic polyadenylated RNA-binding protein PUB1
著者Santiveri, C.M, Mirassou, Y, Rico-Lastres, P, Martinez-Lumbreras, S, Perez-Canadillas, J.M.
登録日2011-03-01
公開日2011-09-28
最終更新日2024-05-15
実験手法SOLUTION NMR
主引用文献Pub1p C-terminal RRM domain interacts with Tif4631p through a conserved region neighbouring the Pab1p binding site
Plos One, 6, 2011
7CBX
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BU of 7cbx by Molmil
Crystal structure of MAP2K7 complexed with a covalent inhibitor 12
分子名称: 3-(1H-indazol-3-yl)-5-(prop-2-enoylamino)-N-prop-2-ynyl-benzamide, Dual specificity mitogen-activated protein kinase kinase 7, GLYCEROL
著者Kinoshita, T, Murakawa, Y.
登録日2020-06-15
公開日2020-09-30
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (2.061 Å)
主引用文献Structural basis for producing selective MAP2K7 inhibitors.
Bioorg.Med.Chem.Lett., 30, 2020
2LHB
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BU of 2lhb by Molmil
REFINEMENT OF A MOLECULAR MODEL FOR LAMPREY HEMOGLOBIN FROM PETROMYZON MARINUS
分子名称: CYANIDE ION, HEMOGLOBIN V (CYANO MET), PROTOPORPHYRIN IX CONTAINING FE
著者Honzatko, R.B, Hendrickson, W.A, Love, W.E.
登録日1985-08-16
公開日1986-01-21
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Refinement of a molecular model for lamprey hemoglobin from Petromyzon marinus.
J.Mol.Biol., 184, 1985
2LJH
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BU of 2ljh by Molmil
NMR structure of Double-stranded RNA-specific editase Adar
分子名称: Double-stranded RNA-specific editase Adar
著者Barraud, P, Allain, F.H.-T.
登録日2011-09-13
公開日2012-01-11
最終更新日2024-05-15
実験手法SOLUTION NMR
主引用文献Solution structure of the N-terminal dsRBD of Drosophila ADAR and interaction studies with RNA.
Biochimie, 94, 2012
3KDD
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BU of 3kdd by Molmil
Crystal Structure of HIV-1 Protease (Q7K, L33I, L63I) in Complex with KNI-10265
分子名称: (4R)-3-[(2S,3S)-3-{[(2,6-difluorophenoxy)acetyl]amino}-2-hydroxy-4-phenylbutanoyl]-N-[(1S,2R)-2-hydroxy-2,3-dihydro-1H- inden-1-yl]-5,5-dimethyl-1,3-thiazolidine-4-carboxamide, GLYCEROL, Protease
著者Chufan, E.E, Kawasaki, Y, Freire, E, Amzel, L.M.
登録日2009-10-22
公開日2010-03-02
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献How much binding affinity can be gained by filling a cavity?
Chem.Biol.Drug Des., 75, 2010
2LKD
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IF2-G2 GDP complex
分子名称: GUANOSINE-5'-DIPHOSPHATE, Translation initiation factor IF-2
著者Wienk, H, Tishchenko, E, Belardinelli, R, Tomaselli, S, Dongre, R, Spurio, R, Folkers, G.E, Gualerzi, C.O, Boelens, R.
登録日2011-10-10
公開日2012-02-15
最終更新日2024-05-15
実験手法SOLUTION NMR
主引用文献Structural Dynamics of Bacterial Translation Initiation Factor IF2.
J.Biol.Chem., 287, 2012
3KUN
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BU of 3kun by Molmil
X-ray structure of the metcyano form of dehaloperoxidase from amphitrite ornata: evidence for photoreductive lysis of iron-cyanide bond
分子名称: CYANIDE ION, Dehaloperoxidase A, PROTOPORPHYRIN IX CONTAINING FE, ...
著者Serrano, V.S, Chen, Z, Gaff, J.F, Rose, R, Franzen, S.
登録日2009-11-27
公開日2010-06-30
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (1.26 Å)
主引用文献X-ray structure of the metcyano form of dehaloperoxidase from Amphitrite ornata: evidence for photoreductive dissociation of the iron-cyanide bond.
Acta Crystallogr.,Sect.D, 66, 2010
2LGC
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BU of 2lgc by Molmil
Joint NMR and X-ray refinement reveals the structure of a novel dibenzo[a,d]cycloheptenone inhibitor/p38 MAP kinase complex in solution
分子名称: Mitogen-activated protein kinase 14
著者Habeck, M.
登録日2011-07-25
公開日2012-07-25
最終更新日2024-05-15
実験手法SOLUTION NMR
主引用文献Inferential NMR/X-ray-based structure determination of a dibenzo[a,d]cycloheptenone inhibitor-p38alpha MAP kinase complex in solution
Angew.Chem.Int.Ed.Engl., 51, 2012
3KXH
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BU of 3kxh by Molmil
Crystal structure of Z. mays CK2 kinase alpha subunit in complex with the inhibitor (2-dymethylammino-4,5,6,7-tetrabromobenzoimidazol-1yl-acetic acid (K66)
分子名称: Casein kinase II subunit alpha, DI(HYDROXYETHYL)ETHER, [4,5,6,7-tetrabromo-2-(dimethylamino)-1H-benzimidazol-1-yl]acetic acid
著者Papinutto, E, Franchin, C, Battistutta, R.
登録日2009-12-03
公開日2010-11-17
最終更新日2017-11-01
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献ATP site-directed inhibitors of protein kinase CK2: an update.
Curr Top Med Chem, 11, 2011
2LGB
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Modified A22Gly-B31Arg Human Insulin
分子名称: Insulin A chain, Insulin B chain
著者Bocian, W, Kozerski, L.
登録日2011-07-25
公開日2012-04-11
最終更新日2023-06-14
実験手法SOLUTION NMR
主引用文献Recombinant A22(G)-B31 (R)-human insulin. A22 addition introduces conformational mobility in B chain C-terminus.
J.Biomol.Nmr, 52, 2012
2L0A
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BU of 2l0a by Molmil
Solution NMR Structure of Signal transducing adapter molecule 1 STAM-1 from Homo sapiens, Northeast Structural Genomics Consortium Target HR4479E
分子名称: Signal transducing adapter molecule 1
著者Tang, Y, Janjua, H, Ciccosanti, C, Shastry, R, Rost, B, Acton, T.B, Xiao, R, Everett, J.K, Montelione, G.T, Northeast Structural Genomics Consortium (NESG)
登録日2010-06-30
公開日2010-07-21
最終更新日2024-05-01
実験手法SOLUTION NMR
主引用文献Northeast Structural Genomics Consortium Target HR4479E
To be Published
3KT2
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Crystal Structure of N88D mutant HIV-1 Protease
分子名称: Protease
著者Bihani, S.C, Das, A, Prashar, V, Ferrer, J.L, Hosur, M.V.
登録日2009-11-24
公開日2010-02-16
最終更新日2024-05-29
実験手法X-RAY DIFFRACTION (1.651 Å)
主引用文献Resistance mechanism revealed by crystal structures of unliganded nelfinavir-resistant HIV-1 protease non-active site mutants N88D and N88S.
Biochem.Biophys.Res.Commun., 389, 2009

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