4A1R
 
 | | The Structure of Serratia marcescens Lip, a membrane bound component of the Type VI Secretion System. | | 分子名称: | 1,2-ETHANEDIOL, LIP, SODIUM ION | | 著者 | Rao, V.A, Shepherd, S.M, English, G, Coulthurst, S.J, Hunter, W.N. | | 登録日 | 2011-09-19 | | 公開日 | 2011-10-05 | | 最終更新日 | 2024-05-01 | | 実験手法 | X-RAY DIFFRACTION (1.92 Å) | | 主引用文献 | The Structure of Serratia Marcescens Lip, a Membrane-Bound Component of the Type Vi Secretion System
Acta Crystallogr.,Sect.F, 67, 2011
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7R58
 | | Crystal structure of the GPVI-glenzocimab complex | | 分子名称: | CHLORIDE ION, Fab heavy chain, Fab light chain, ... | | 著者 | Jandrot-Perrus, M, Lebozec, K, Rose, N, Welin, M, Billiald, P. | | 登録日 | 2022-02-10 | | 公開日 | 2022-11-16 | | 最終更新日 | 2024-02-07 | | 実験手法 | X-RAY DIFFRACTION (1.902 Å) | | 主引用文献 | Targeting platelet GPVI with glenzocimab: a novel mechanism for inhibition.
Blood Adv, 7, 2023
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5OP6
 | | Factor Inhibiting HIF (FIH) in complex with zinc and GSK128863 | | 分子名称: | 2-[[1,3-dicyclohexyl-4-oxidanyl-2,6-bis(oxidanylidene)pyrimidin-5-yl]carbonylamino]ethanoic acid, GLYCEROL, Hypoxia-inducible factor 1-alpha inhibitor, ... | | 著者 | Leissing, T.M, Schofield, C.J, Clifton, I.J, Thinnes, C.C, Lu, X. | | 登録日 | 2017-08-09 | | 公開日 | 2017-10-18 | | 最終更新日 | 2024-01-17 | | 実験手法 | X-RAY DIFFRACTION (2.45 Å) | | 主引用文献 | Molecular and cellular mechanisms of HIF prolyl hydroxylase inhibitors in clinical trials.
Chem Sci, 8, 2017
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7R4S
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7R56
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1LYD
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2VOV
 | | An oxidized tryptophan facilitates copper-binding in Methylococcus capsulatus secreted protein MopE. The structure of wild-type MopE to 1.35AA | | 分子名称: | CALCIUM ION, COPPER (II) ION, SURFACE-ASSOCIATED PROTEIN | | 著者 | Helland, R, Fjellbirkeland, A, Karlsen, O.A, Ve, T, Lillehaug, J.R, Jensen, H.B. | | 登録日 | 2008-02-22 | | 公開日 | 2008-03-18 | | 最終更新日 | 2023-12-13 | | 実験手法 | X-RAY DIFFRACTION (1.35 Å) | | 主引用文献 | An Oxidized Tryptophan Facilitates Copper Binding in Methylococcus Capsulatus-Secreted Protein Mope.
J.Biol.Chem., 283, 2008
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7SFX
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5OP8
 | | Factor Inhibiting HIF (FIH) in complex with zinc and Molidustat | | 分子名称: | 2-(6-morpholin-4-ylpyrimidin-4-yl)-4-(1,2,3-triazol-1-yl)-1~{H}-pyrazol-3-one, GLYCEROL, Hypoxia-inducible factor 1-alpha inhibitor, ... | | 著者 | Leissing, T.M, Schofield, C.J, Clifton, I.J, Lu, X. | | 登録日 | 2017-08-09 | | 公開日 | 2017-10-18 | | 最終更新日 | 2024-01-17 | | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | | 主引用文献 | Molecular and cellular mechanisms of HIF prolyl hydroxylase inhibitors in clinical trials.
Chem Sci, 8, 2017
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3ZH4
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7RW8
 | | AP2 bound to heparin in the closed conformation | | 分子名称: | AP-2 complex subunit alpha-2, AP-2 complex subunit beta, AP-2 complex subunit mu, ... | | 著者 | Baker, R.W, Hollopeter, G, Partlow, E.A. | | 登録日 | 2021-08-19 | | 公開日 | 2022-03-30 | | 最終更新日 | 2024-06-05 | | 実験手法 | ELECTRON MICROSCOPY (3.5 Å) | | 主引用文献 | Structural basis of an endocytic checkpoint that primes the AP2 clathrin adaptor for cargo internalization.
Nat.Struct.Mol.Biol., 29, 2022
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7S3R
 | | NMR Solution Structure of hGal(1-12)KK, a solubility-tagged truncation of the human neuropeptide galanin | | 分子名称: | Galanin | | 著者 | Kraichely, K.N, Mendoza, E.A, Parnham, S, Giuliano, M.W. | | 登録日 | 2021-09-08 | | 公開日 | 2022-05-25 | | 最終更新日 | 2022-07-06 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Minimal Increments of Hydrophobic Collapse within the N-Terminus of the Neuropeptide Galanin.
Biochemistry, 61, 2022
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7SAP
 | | The CTI-homolog pacifastin | | 分子名称: | GLYCEROL, Serine protease inhibitor I/II-like Protein | | 著者 | Gewe, M.M, Strong, R.K. | | 登録日 | 2021-09-23 | | 公開日 | 2022-08-03 | | 最終更新日 | 2023-10-18 | | 実験手法 | X-RAY DIFFRACTION (1.79 Å) | | 主引用文献 | Ex silico engineering of cystine-dense peptides yielding a potent bispecific T cell engager.
Sci Transl Med, 14, 2022
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5TC1
 | | In situ structures of the genome and genome-delivery apparatus in ssRNA bacteriophage MS2 | | 分子名称: | Capsid protein, Maturation protein, phage MS2 genome | | 著者 | Dai, X.H, Li, Z.H, Lai, M, Shu, S, Du, Y.S, Zhou, Z.H, Sun, R. | | 登録日 | 2016-09-13 | | 公開日 | 2016-12-07 | | 最終更新日 | 2018-07-18 | | 実験手法 | ELECTRON MICROSCOPY (3.6 Å) | | 主引用文献 | In situ structures of the genome and genome-delivery apparatus in a single-stranded RNA virus.
Nature, 541, 2017
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3ZH8
 | | A novel small molecule aPKC inhibitor | | 分子名称: | (2S)-3-phenyl-N~1~-[2-(pyridin-4-yl)-5,6,7,8-tetrahydro[1]benzothieno[2,3-d]pyrimidin-4-yl]propane-1,2-diamine, 1,2-ETHANEDIOL, CHLORIDE ION, ... | | 著者 | Kjaer, S, Purkiss, A.G, Kostelecky, B, Knowles, P.P, Soriano, E, Murray-Rust, J, McDonald, N.Q. | | 登録日 | 2012-12-20 | | 公開日 | 2013-02-27 | | 最終更新日 | 2023-12-20 | | 実験手法 | X-RAY DIFFRACTION (2.739 Å) | | 主引用文献 | Adenosine-Binding Motif Mimicry and Cellular Effects of a Thieno[2,3-D]Pyrimidine-Based Chemical Inhibitor of Atypical Protein Kinase C Isozymes.
Biochem.J., 451, 2013
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2XVA
 | | Crystal structure of the tellurite detoxification protein TehB from E. coli in complex with sinefungin | | 分子名称: | SINEFUNGIN, TELLURITE RESISTANCE PROTEIN TEHB, ZINC ION | | 著者 | Choudhury, H.G, Cameron, A.D, Iwata, S, Beis, K. | | 登録日 | 2010-10-25 | | 公開日 | 2011-02-16 | | 最終更新日 | 2023-12-20 | | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | | 主引用文献 | Structure and Mechanism of the Chalcogen Detoxifying Protein Tehb from Escherichia Coli.
Biochem.J., 435, 2011
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5W0W
 | | Crystal structure of Protein Phosphatase 2A bound to TIPRL | | 分子名称: | MANGANESE (II) ION, Serine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A alpha isoform, Serine/threonine-protein phosphatase 2A catalytic subunit alpha isoform, ... | | 著者 | Wu, C, Zheng, A, Li, J, Satyshur, K, Xing, Y. | | 登録日 | 2017-06-01 | | 公開日 | 2018-01-17 | | 最終更新日 | 2020-01-01 | | 実験手法 | X-RAY DIFFRACTION (3.8 Å) | | 主引用文献 | Methylation-regulated decommissioning of multimeric PP2A complexes.
Nat Commun, 8, 2017
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5WAM
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9EQG
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9C57
 | | Reconstituted P400 Subcomplex of the human TIP60 complex | | 分子名称: | ADENOSINE-5'-TRIPHOSPHATE, Actin, cytoplasmic 1, ... | | 著者 | Yang, Z, Mameri, A, Florez Ariza, A.J, Cote, J, Nogales, E. | | 登録日 | 2024-06-05 | | 公開日 | 2024-08-21 | | 最終更新日 | 2024-09-11 | | 実験手法 | ELECTRON MICROSCOPY (2.75 Å) | | 主引用文献 | Structural insights into the human NuA4/TIP60 acetyltransferase and chromatin remodeling complex.
Science, 385, 2024
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9IMA
 | | Cryo-EM structure for the GPRC5D complexed with Talquetamab Fab | | 分子名称: | CHOLESTEROL, G-protein coupled receptor family C group 5 member D, Talquetamab Fab (anti-GPRC5D) Heavy chain, ... | | 著者 | Jeong, J, Shin, J, Park, J, Cho, Y. | | 登録日 | 2024-07-02 | | 公開日 | 2024-09-11 | | 実験手法 | ELECTRON MICROSCOPY (2.65 Å) | | 主引用文献 | Structural Basis for the Recognition of GPRC5D by Talquetamab, a Bispecific Antibody for Multiple Myeloma.
J.Mol.Biol., 436, 2024
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9FAA
 | | Cryo-EM structure of cardiac collagen-associated amyloid AL59 | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Monoclonal immunoglobulin light chains (LC) | | 著者 | Schulte, T, Speranzini, V, Chaves-Sanjuan, A, Milazzo, M, Ricagno, S. | | 登録日 | 2024-05-10 | | 公開日 | 2024-07-17 | | 最終更新日 | 2024-08-14 | | 実験手法 | ELECTRON MICROSCOPY (3.6 Å) | | 主引用文献 | Helical superstructures between amyloid and collagen in cardiac fibrils from a patient with AL amyloidosis.
Nat Commun, 15, 2024
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9J9A
 | | Staphylococcus aureus exfoliative toxin D | | 分子名称: | SULFATE ION, Serine protease, beta-D-glucopyranose | | 著者 | Tonozuka, T. | | 登録日 | 2024-08-22 | | 公開日 | 2024-09-11 | | 最終更新日 | 2024-09-25 | | 実験手法 | X-RAY DIFFRACTION (1.75 Å) | | 主引用文献 | Crystal structure of exfoliative toxin D from Staphylococcus aureus.
Biochem.Biophys.Res.Commun., 733, 2024
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9C8U
 | | Human PRC2 - RvLEAM (short) (1:6 molar ratio), cross-linked 10 min | | 分子名称: | Isoform 2 of Histone-lysine N-methyltransferase EZH2, Polycomb protein EED, Polycomb protein SUZ12, ... | | 著者 | Abe, K.M, Li, G, He, Q, Grant, T, Lim, C. | | 登録日 | 2024-06-13 | | 公開日 | 2024-09-04 | | 実験手法 | ELECTRON MICROSCOPY (3.1 Å) | | 主引用文献 | Human PRC2 - RvLEAM (short) (1:6 molar ratio), cross-linked 10 min
To Be Published
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9FAC
 | | Additional cryo-EM structure of cardiac amyloid AL59 - mixed polymorph | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Monoclonal immunoglobulin light chains (LC) | | 著者 | Schulte, T, Speranzini, V, Chaves-Sanjuan, A, Milazzo, M, Ricagno, S. | | 登録日 | 2024-05-10 | | 公開日 | 2024-08-14 | | 最終更新日 | 2024-08-28 | | 実験手法 | ELECTRON MICROSCOPY (3.9 Å) | | 主引用文献 | Helical superstructures between amyloid and collagen in cardiac fibrils from a patient with AL amyloidosis.
Nat Commun, 15, 2024
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