7WX0
 
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7WWT
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7WX1
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4A7U
 | | Structure of human I113T SOD1 complexed with adrenaline in the p21 space group. | | 分子名称: | ACETATE ION, COPPER (II) ION, L-EPINEPHRINE, ... | | 著者 | Wright, G.S.A, Kershaw, N.M, Antonyuk, S.V, Strange, R.W, ONeil, P.M, Hasnain, S.S. | | 登録日 | 2011-11-14 | | 公開日 | 2012-11-28 | | 最終更新日 | 2013-05-08 | | 実験手法 | X-RAY DIFFRACTION (0.98 Å) | | 主引用文献 | Ligand Binding and Aggregation of Pathogenic Sod1.
Nat.Commun., 4, 2013
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4A7T
 | | Structure of human I113T SOD1 mutant complexed with isoproteranol in the p21 space group | | 分子名称: | ACETATE ION, COPPER (II) ION, ISOPRENALINE, ... | | 著者 | Wright, G.S.A, Kershaw, N.M, Antonyuk, S.V, Strange, R.W, ONeil, P.M, Hasnain, S.S. | | 登録日 | 2011-11-14 | | 公開日 | 2012-11-28 | | 最終更新日 | 2013-05-08 | | 実験手法 | X-RAY DIFFRACTION (1.45 Å) | | 主引用文献 | Ligand Binding and Aggregation of Pathogenic Sod1.
Nat.Commun., 4, 2013
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4A7S
 | | Structure of human I113T SOD1 mutant complexed with 5-Fluorouridine in the p21 space group | | 分子名称: | 5-FLUOROURIDINE, ACETATE ION, COPPER (II) ION, ... | | 著者 | Wright, G.S.A, Kershaw, N.M, Antonyuk, S.V, Strange, R.W, ONeil, P.M, Hasnain, S.S. | | 登録日 | 2011-11-14 | | 公開日 | 2012-12-05 | | 最終更新日 | 2013-05-08 | | 実験手法 | X-RAY DIFFRACTION (1.06 Å) | | 主引用文献 | Ligand Binding and Aggregation of Pathogenic Sod1.
Nat.Commun., 4, 2013
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4A7V
 | | Structure of human I113T SOD1 mutant complexed with dopamine in the p21 space group | | 分子名称: | COPPER (II) ION, L-DOPAMINE, SULFATE ION, ... | | 著者 | Wright, G.S.A, Antonyuk, S.V, Kershaw, N.M, Strange, R.W, Hasnain, S.S. | | 登録日 | 2011-11-14 | | 公開日 | 2012-11-28 | | 最終更新日 | 2013-05-08 | | 実験手法 | X-RAY DIFFRACTION (1 Å) | | 主引用文献 | Ligand Binding and Aggregation of Pathogenic Sod1.
Nat.Commun., 4, 2013
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6FOL
 | | Domain II of the human copper chaperone in complex with human Cu,Zn superoxide dismutase | | 分子名称: | 3,6,9,12,15,18,21-HEPTAOXATRICOSANE-1,23-DIOL, Copper chaperone for superoxide dismutase, GLYCEROL, ... | | 著者 | Sala, F.A, Wright, G.S.A, Antonyuk, S.V, Garratt, R.C, Hasnain, S.S. | | 登録日 | 2018-02-07 | | 公開日 | 2019-01-30 | | 最終更新日 | 2024-01-17 | | 実験手法 | X-RAY DIFFRACTION (2.55 Å) | | 主引用文献 | Molecular recognition and maturation of SOD1 by its evolutionarily destabilised cognate chaperone hCCS.
Plos Biol., 17, 2019
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6FN8
 | | Domain II of the HUMAN COPPER CHAPERONE FOR SUPEROXIDE DISMUTASE at 1.55 A resolution | | 分子名称: | Copper chaperone for superoxide dismutase, ZINC ION | | 著者 | Sala, F.A, Wright, G.S.A, Antonyuk, S.V, Garratt, R.C, Hasnain, S.S. | | 登録日 | 2018-02-02 | | 公開日 | 2019-01-30 | | 最終更新日 | 2019-06-19 | | 実験手法 | X-RAY DIFFRACTION (1.55 Å) | | 主引用文献 | Molecular recognition and maturation of SOD1 by its evolutionarily destabilised cognate chaperone hCCS.
Plos Biol., 17, 2019
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2VR6
 | | Crystal Structure of G85R ALS mutant of Human Cu,Zn Superoxide Dismutase (CuZnSOD) at 1.3 A resolution | | 分子名称: | COPPER (II) ION, SULFATE ION, SUPEROXIDE DISMUTASE [CU-ZN], ... | | 著者 | Antonyuk, S, Cao, X, Seetharaman, S.V, Whitson, L.J, Taylor, A.B, Holloway, S.P, Strange, R.W, Doucette, P.A, Tiwari, A, Hayward, L.J, Padua, S, Cohlberg, J.A, Selverstone Valentine, J, Hasnain, S.S, Hart, P.J. | | 登録日 | 2008-03-28 | | 公開日 | 2008-04-15 | | 最終更新日 | 2023-12-13 | | 実験手法 | X-RAY DIFFRACTION (1.3 Å) | | 主引用文献 | Structures of the G85R Variant of Sod1 in Familial Amyotrophic Lateral Sclerosis.
J.Biol.Chem., 283, 2008
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2VR7
 | | Crystal Structure of G85R ALS mutant of Human Cu,Zn Superoxide Dismutase (CuZnSOD) at 1.58 A resolution | | 分子名称: | COPPER (II) ION, SULFATE ION, SUPEROXIDE DISMUTASE [CU-ZN], ... | | 著者 | Antonyuk, S, Cao, X, Seetharaman, S.V, Whitson, L.J, Taylor, A.B, Holloway, S.P, Strange, R.W, Doucette, P.A, Tiwari, A, Hayward, L.J, Padua, S, Cohlberg, J.A, Selverstone Valentine, J, Hasnain, S.S, Hart, P.J. | | 登録日 | 2008-03-28 | | 公開日 | 2008-04-15 | | 最終更新日 | 2023-12-13 | | 実験手法 | X-RAY DIFFRACTION (1.58 Å) | | 主引用文献 | Structures of the G85R Variant of Sod1 in Familial Amyotrophic Lateral Sclerosis.
J.Biol.Chem., 283, 2008
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2VR8
 | | Crystal Structure of G85R ALS mutant of Human Cu,Zn Superoxide Dismutase (CuZnSOD) at 1.36 A resolution | | 分子名称: | COPPER (II) ION, SULFATE ION, SUPEROXIDE DISMUTASE [CU-ZN], ... | | 著者 | Antonyuk, S, Cao, X, Seetharaman, S.V, Whitson, L.J, Taylor, A.B, Holloway, S.P, Strange, R.W, Doucette, P.A, Tiwari, A, Hayward, L.J, Padua, S, Cohlberg, J.A, Selverstone Valentine, J, Hasnain, S.S, Hart, P.J. | | 登録日 | 2008-03-28 | | 公開日 | 2008-04-08 | | 最終更新日 | 2023-12-13 | | 実験手法 | X-RAY DIFFRACTION (1.36 Å) | | 主引用文献 | Structures of the G85R Variant of Sod1 in Familial Amyotrophic Lateral Sclerosis.
J.Biol.Chem., 283, 2008
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1OZU
 | | Crystal Structure of Familial ALS Mutant S134N of human Cu,Zn Superoxide Dismutase (CuZnSOD) to 1.3A resolution | | 分子名称: | SULFATE ION, Superoxide dismutase [Cu-Zn], ZINC ION | | 著者 | Elam, J.S, Taylor, A.B, Strange, R, Antonyuk, S, Doucette, P.A, Rodriguez, J.A, Hasnain, S.S, Hayward, L.J, Valentine, J.S, Yeates, T.O, Hart, P.J. | | 登録日 | 2003-04-09 | | 公開日 | 2003-05-27 | | 最終更新日 | 2023-08-16 | | 実験手法 | X-RAY DIFFRACTION (1.3 Å) | | 主引用文献 | Amyloid-like Filaments and Water-filled Nanotubes Formed by SOD1 Mutant Proteins Linked to Familial ALS
Nat.Struct.Biol., 10, 2003
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1OZT
 | | Crystal Structure of apo-H46R Familial ALS Mutant human Cu,Zn Superoxide Dismutase (CuZnSOD) to 2.5A resolution | | 分子名称: | Superoxide dismutase [Cu-Zn] | | 著者 | Elam, J.S, Taylor, A.B, Strange, R, Antonyuk, S, Doucette, P.A, Rodriguez, J.A, Hasnain, S.S, Hayward, L.J, Valentine, J.S, Yeates, T.O, Hart, P.J. | | 登録日 | 2003-04-09 | | 公開日 | 2003-05-27 | | 最終更新日 | 2023-08-16 | | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | | 主引用文献 | Amyloid-like Filaments and Water-filled Nanotubes Formed by SOD1 Mutant Proteins Linked to Familial ALS
Nat.Struct.Biol., 10, 2003
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1OEZ
 | | Zn His46Arg mutant of Human Cu, Zn Superoxide Dismutase | | 分子名称: | SULFATE ION, SUPEROXIDE DISMUTASE [CU-ZN], ZINC ION | | 著者 | Strange, R.W, Antonyuk, S, Hough, M.A, Doucette, P, Rodriguez, J, Elam, J.S, Hart, P.J, Hayward, L.J, Valentine, J.S, Hasnain, S.S. | | 登録日 | 2003-04-02 | | 公開日 | 2003-05-29 | | 最終更新日 | 2023-12-13 | | 実験手法 | X-RAY DIFFRACTION (2.15 Å) | | 主引用文献 | Amyloid-Like Filaments and Water-Filled Nanotubes Formed by Sod1 Mutant Proteins Linked to Familial Als
Nat.Struct.Biol., 10, 2003
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3HFF
 | | Monomeric human Cu,Zn Superoxide dismutase without Zn ligands | | 分子名称: | Superoxide dismutase [Cu-Zn], ZINC ION | | 著者 | Saraboji, K, Nordlund, A, Leinartait, L, Oliveberg, M, Logan, D.T. | | 登録日 | 2009-05-11 | | 公開日 | 2009-06-16 | | 最終更新日 | 2024-05-29 | | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | | 主引用文献 | Functional features cause misfolding of the ALS-provoking enzyme SOD1.
Proc.Natl.Acad.Sci.USA, 106, 2009
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2RSQ
 | | Copper(I) loaded form of the first domain of the human copper chaperone for SOD1, CCS | | 分子名称: | COPPER (I) ION, Copper chaperone for superoxide dismutase | | 著者 | Banci, L, Bertini, I, Cantini, F, Kozyreva, T, Rubino, J.T. | | 登録日 | 2012-05-15 | | 公開日 | 2013-04-03 | | 最終更新日 | 2024-05-01 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Copper(I) loaded form of the first domain of the human copper chaperone for SOD1, CCS
To be Published
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7XX3
 | | Crystal structure of human Superoxide Dismutase (SOD1) in complex with a fungal metabolite molecule, Phialomustin B (PB) | | 分子名称: | (2~{E},4~{E},6~{S})-4,6-dimethyldeca-2,4-dienoic acid, DIMETHYL SULFOXIDE, GLYCEROL, ... | | 著者 | Padmanabhan, B, Unni, S. | | 登録日 | 2022-05-28 | | 公開日 | 2023-12-13 | | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | | 主引用文献 | Phialomustin-B a fungal metabolite isolated from Phialophora mustea modulates Superoxide Dismutase 1 (SOD1) aggregation: Therapeutic potential in Amyotrophic lateral sclerosis (ALS)
To Be Published
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5WMJ
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4MNT
 | | Crystal structure of human DJ-1 in complex with Cu | | 分子名称: | COPPER (II) ION, Protein DJ-1 | | 著者 | Cendron, L, Girotto, S, Bisaglia, M, Tessari, I, Mammi, S, Zanotti, G, Bubacco, L. | | 登録日 | 2013-09-11 | | 公開日 | 2014-03-05 | | 最終更新日 | 2024-02-28 | | 実験手法 | X-RAY DIFFRACTION (1.584 Å) | | 主引用文献 | DJ-1 Is a Copper Chaperone Acting on SOD1 Activation.
J.Biol.Chem., 289, 2014
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4N0M
 | | Crystal structure of human C53A DJ-1 in complex with Cu | | 分子名称: | 1,2-ETHANEDIOL, COPPER (II) ION, Protein DJ-1 | | 著者 | Cendron, L, Girotto, S, Bisaglia, M, Tessari, I, Mammi, S, Zanotti, G, Bubacco, L. | | 登録日 | 2013-10-02 | | 公開日 | 2014-03-05 | | 最終更新日 | 2024-02-28 | | 実験手法 | X-RAY DIFFRACTION (1.95 Å) | | 主引用文献 | DJ-1 Is a Copper Chaperone Acting on SOD1 Activation.
J.Biol.Chem., 289, 2014
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4MTC
 | | Crystal structure of human C53A DJ-1 | | 分子名称: | 1,2-ETHANEDIOL, Protein DJ-1 | | 著者 | Cendron, L, Girotto, S, Bisaglia, M, Tessari, I, Mammi, S, Zanotti, G, Bubacco, L. | | 登録日 | 2013-09-19 | | 公開日 | 2014-03-05 | | 最終更新日 | 2024-02-28 | | 実験手法 | X-RAY DIFFRACTION (1.47 Å) | | 主引用文献 | DJ-1 Is a Copper Chaperone Acting on SOD1 Activation.
J.Biol.Chem., 289, 2014
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4N12
 | | Crystal structure of human E18D DJ-1 in complex with Cu | | 分子名称: | 1,2-ETHANEDIOL, COPPER (II) ION, Protein DJ-1 | | 著者 | Cendron, L, Girotto, S, Bisaglia, M, Tessari, I, Mammi, S, Zanotti, G, Bubacco, L. | | 登録日 | 2013-10-03 | | 公開日 | 2014-03-05 | | 最終更新日 | 2014-11-12 | | 実験手法 | X-RAY DIFFRACTION (1.478 Å) | | 主引用文献 | DJ-1 Is a Copper Chaperone Acting on SOD1 Activation.
J.Biol.Chem., 289, 2014
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3H2P
 | | Human SOD1 D124V Variant | | 分子名称: | ACETYL GROUP, MALONATE ION, Superoxide dismutase [Cu-Zn], ... | | 著者 | Seetharaman, S.V, Winkler, D.D, Taylor, A.B, Cao, X, Whitson, L.J, Doucette, P.A, Valentine, J.S, Carroll, M.C, Culotta, V.C, Hart, P.J. | | 登録日 | 2009-04-14 | | 公開日 | 2010-05-05 | | 最終更新日 | 2023-09-06 | | 実験手法 | X-RAY DIFFRACTION (1.55 Å) | | 主引用文献 | Structures of Pathogenic SOD1 Mutants H80R and D124V: Disrupted Zinc-binding
and Compromised Post-translational Modification by the Copper Chaperone CCS
To be Published
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3H2Q
 | | Human SOD1 H80R variant, P21 crystal form | | 分子名称: | SULFATE ION, Superoxide dismutase [Cu-Zn], ZINC ION | | 著者 | Seetharaman, S.V, Winkler, D.D, Taylor, A.B, Cao, X, Whitson, L.J, Doucette, P.A, Valentine, J.S, Carroll, M.C, Culotta, V.C, Hart, P.J. | | 登録日 | 2009-04-14 | | 公開日 | 2010-05-05 | | 最終更新日 | 2023-09-06 | | 実験手法 | X-RAY DIFFRACTION (1.85 Å) | | 主引用文献 | Structures of Pathogenic SOD1 Mutants H80R and D124V: Disrupted Zinc-binding
and Compromised Post-translational Modification by the Copper Chaperone CCS
To be Published
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