4MTC

Crystal structure of human C53A DJ-1

Summary for 4MTC

• Entry DOI: 10.2210/pdb4mtc/pdb
• Related: 4MNT
• Descriptor: Protein DJ-1, 1,2-ETHANEDIOL (3 entities in total)
• Functional Keywords: homodimer, rossmann fold, alpha/beta protein, chaperone, oxidative stress protection, cytosol, mitochondrion, nucleus, hydrolase
• Biological source: Homo sapiens (human)
• Cellular location: Cell membrane; Lipid-anchor: Q99497
• Total number of polymer chains: 1
• Total formula weight: 19947.05

Authors

Cendron, L.,Girotto, S.,Bisaglia, M.,Tessari, I.,Mammi, S.,Zanotti, G.,Bubacco, L. (deposition date: 2013-09-19, release date: 2014-03-05, Last modification date: 2024-02-28)

• Primary citation: Girotto, S.,Cendron, L.,Bisaglia, M.,Tessari, I.,Mammi, S.,Zanotti, G.,Bubacco, L.; DJ-1 Is a Copper Chaperone Acting on SOD1 Activation.; J.Biol.Chem., 289:10887-10899, 2014; PubMed: 24567322; DOI: 10.1074/jbc.M113.535112

Experimental method

X-RAY DIFFRACTION (1.47 Å)