4MNT

Crystal structure of human DJ-1 in complex with Cu

Summary for 4MNT

Entry DOI	10.2210/pdb4mnt/pdb
Descriptor	Protein DJ-1, COPPER (II) ION (3 entities in total)
Functional Keywords	protein-metal complex, flavodoxin-like fold, rossmann fold, chaperone, copper binding, cysteine oxidation, hydrolase
Biological source	Homo sapiens (human)
Cellular location	Cell membrane ; Lipid-anchor : Q99497
Total number of polymer chains	1
Total formula weight	20044.14
Authors	Cendron, L.,Girotto, S.,Bisaglia, M.,Tessari, I.,Mammi, S.,Zanotti, G.,Bubacco, L. (deposition date: 2013-09-11, release date: 2014-03-05, Last modification date: 2024-02-28)
Primary citation	Girotto, S.,Cendron, L.,Bisaglia, M.,Tessari, I.,Mammi, S.,Zanotti, G.,Bubacco, L. DJ-1 Is a Copper Chaperone Acting on SOD1 Activation. J.Biol.Chem., 289:10887-10899, 2014 Cited by PubMed: 24567322 DOI: 10.1074/jbc.M113.535112 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.584 Å)

Structure validation