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3W9G
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Crystal structure of the ankyrin repeat domain of chicken TRPV4
分子名称: Vanilloid receptor-related osmotically activated channel protein
著者Itoh, Y, Hamada-nakahara, S, Suetsugu, S.
登録日2013-04-04
公開日2014-04-09
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献TRPV4 channel activity is modulated by direct interaction of the ankyrin domain to PI(4,5)P2
Nat Commun, 5, 2014
4QQI
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Crystal structure of ANKRA2-RFX7 complex
分子名称: Ankyrin repeat family A protein 2, DNA-binding protein RFX7, SULFATE ION, ...
著者Xu, C, Tempel, W, Dong, A, Mackenzie, F, Bountra, C, Arrowsmith, C.H, Edwards, A.M, Min, J, Structural Genomics Consortium (SGC)
登録日2014-06-27
公開日2014-09-03
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (2.03 Å)
主引用文献Crystal structure of ANKRA2-RFX7 complex
To Be Published
4RLV
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Crystal Structure of AnkB 24 Ankyrin Repeats in Complex with AnkR Autoinhibition Segment
分子名称: Ankyrin-1, Ankyrin-2, SULFATE ION
著者Wei, Z, Wang, C, Zhang, M.
登録日2014-10-18
公開日2014-11-26
最終更新日2017-11-22
実験手法X-RAY DIFFRACTION (3.4945 Å)
主引用文献Structural basis of diverse membrane target recognitions by ankyrins.
Elife, 3, 2014
4RLY
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Crystal Structure of AnkB Ankyrin Repeats (R1-R9) in Complex with Nav1.2 Ankyrin Binding Domain
分子名称: Nav1.2 - AnkB chimera, SULFATE ION
著者Wei, Z, Wang, C, Zhang, M.
登録日2014-10-18
公開日2014-11-26
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (2.5032 Å)
主引用文献Structural basis of diverse membrane target recognitions by ankyrins.
Elife, 3, 2014
4OT9
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BU of 4ot9 by Molmil
crystal structure of the C-terminal domain of p100/NF-kB2
分子名称: Nuclear factor NF-kappa-B p100 subunit, SULFATE ION
著者Tao, Z.H, Huang, D.B, Fusco, A, Gupta, K, Ware, C.F, Duynne, G.V.
登録日2014-02-13
公開日2015-01-14
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (3.35 Å)
主引用文献p100/I kappa B delta sequesters and inhibits NF-kappa B through kappaBsome formation.
Proc.Natl.Acad.Sci.USA, 111, 2014
3J9P
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Structure of the TRPA1 ion channel determined by electron cryo-microscopy
分子名称: Maltose-binding periplasmic protein, Transient receptor potential cation channel subfamily A member 1 chimera
著者Paulsen, C.E, Armache, J.-P, Gao, Y, Cheng, Y, Julius, D.
登録日2015-02-14
公開日2015-04-08
最終更新日2024-05-15
実験手法ELECTRON MICROSCOPY (4.24 Å)
主引用文献Structure of the TRPA1 ion channel suggests regulatory mechanisms.
Nature, 520, 2015
3J9J
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Structure of the capsaicin receptor, TRPV1, determined by single particle electron cryo-microscopy
分子名称: Transient receptor potential cation channel subfamily V member 1
著者Wang, R.Y.-R, Barad, B.A, Fraser, J.S, DiMaio, F.
登録日2015-02-02
公開日2015-09-02
最終更新日2024-02-21
実験手法ELECTRON MICROSCOPY (3.275 Å)
主引用文献EMRinger: side chain-directed model and map validation for 3D cryo-electron microscopy.
Nat.Methods, 12, 2015
5CZY
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Crystal structure of LegAS4
分子名称: GLYCEROL, Legionella effector LegAS4, S-ADENOSYLMETHIONINE
著者Son, J, Hwang, K.Y, Lee, W.C.
登録日2015-08-01
公開日2015-09-23
最終更新日2024-04-03
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Crystal structure of Legionella pneumophila type IV secretion system effector LegAS4
Biochem.Biophys.Res.Commun., 465, 2015
5D68
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Crystal structure of KRIT1 ARD-FERM
分子名称: Krev interaction trapped protein 1
著者Zhang, R, Li, X, Boggon, T.J.
登録日2015-08-11
公開日2015-10-21
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (2.908 Å)
主引用文献Structural analysis of the KRIT1 ankyrin repeat and FERM domains reveals a conformationally stable ARD-FERM interface.
J.Struct.Biol., 192, 2015
5IS0
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Structure of TRPV1 in complex with capsazepine, determined in lipid nanodisc
分子名称: Transient receptor potential cation channel subfamily V member 1, capsazepine
著者Gao, Y, Cao, E, Julius, D, Cheng, Y.
登録日2016-03-15
公開日2016-05-25
最終更新日2024-03-06
実験手法ELECTRON MICROSCOPY (3.43 Å)
主引用文献TRPV1 structures in nanodiscs reveal mechanisms of ligand and lipid action.
Nature, 534, 2016
5IRX
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Structure of TRPV1 in complex with DkTx and RTX, determined in lipid nanodisc
分子名称: (2S)-2-(acetyloxy)-3-{[(R)-(2-aminoethoxy)(hydroxy)phosphoryl]oxy}propyl pentanoate, (2S)-3-{[(S)-(2-aminoethoxy)(hydroxy)phosphoryl]oxy}-2-(hexanoyloxy)propyl hexanoate, (4R,7S)-4-hydroxy-N,N,N-trimethyl-4,9-dioxo-7-[(pentanoyloxy)methyl]-3,5,8-trioxa-4lambda~5~-phosphatetradecan-1-aminium, ...
著者Gao, Y, Cao, E, Julius, D, Cheng, Y.
登録日2016-03-14
公開日2016-05-25
最終更新日2019-12-18
実験手法ELECTRON MICROSCOPY (2.95 Å)
主引用文献TRPV1 structures in nanodiscs reveal mechanisms of ligand and lipid action.
Nature, 534, 2016
5IRZ
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Structure of TRPV1 determined in lipid nanodisc
分子名称: (2S)-1-{[(R)-hydroxy{[(1R,2R,3S,4S,5S,6S)-2,3,4,5,6-pentahydroxycyclohexyl]oxy}phosphoryl]oxy}-3-(pentanoyloxy)propan-2-yl decanoate, (2S)-3-{[(S)-(2-aminoethoxy)(hydroxy)phosphoryl]oxy}-2-(hexanoyloxy)propyl hexanoate, (4R,7S)-4-hydroxy-N,N,N-trimethyl-4,9-dioxo-7-[(pentanoyloxy)methyl]-3,5,8-trioxa-4lambda~5~-phosphatetradecan-1-aminium, ...
著者Gao, Y, Cao, E, Julius, D, Cheng, Y.
登録日2016-03-15
公開日2016-05-25
最終更新日2024-03-06
実験手法ELECTRON MICROSCOPY (3.28 Å)
主引用文献TRPV1 structures in nanodiscs reveal mechanisms of ligand and lipid action.
Nature, 534, 2016
5JA4
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Crystal structure of human TONSL and MCM2 HBDs binding to a histone H3-H4 tetramer
分子名称: 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, DNA replication licensing factor MCM2, GLYCEROL, ...
著者Huang, H, Patel, D.
登録日2016-04-11
公開日2016-06-15
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (2.424 Å)
主引用文献H4K20me0 marks post-replicative chromatin and recruits the TONSL-MMS22L DNA repair complex.
Nature, 534, 2016
5AAR
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Structure of the ankyrin domain of an Arabidopsis Thaliana potassium channel
分子名称: MAGNESIUM ION, POTASSIUM CHANNEL AKT1
著者Chaves-Sanjuan, A, Sanchez-Barrena, M.J, Albert, A.
登録日2015-07-28
公開日2016-08-24
最終更新日2024-01-10
実験手法X-RAY DIFFRACTION (1.87 Å)
主引用文献Recognition and activation of the plant AKT1 potassium channel by the kinase CIPK23.
Plant Physiol., 2020
5JHQ
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ARCs 1-3 of human Tankyrase-1 bound to a peptide derived from IRAP
分子名称: Peptide derived from insulin-responsive aminopeptidase (IRAP), Tankyrase-1
著者Eisemann, T, Pascal, J.M.
登録日2016-04-21
公開日2016-09-21
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (3.2 Å)
主引用文献Tankyrase-1 Ankyrin Repeats Form an Adaptable Binding Platform for Targets of ADP-Ribose Modification.
Structure, 24, 2016
5H2C
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Crystal structure of Saccharomyces cerevisiae Osh1 ANK - Nvj1
分子名称: Nucleus-vacuole junction protein 1, Oxysterol-binding protein homolog 1
著者Im, Y.J, Manik, M.K, Yang, H.S, Tong, J.S.
登録日2016-10-14
公開日2017-05-10
最終更新日2024-03-20
実験手法X-RAY DIFFRACTION (3.508 Å)
主引用文献Structure of Yeast OSBP-Related Protein Osh1 Reveals Key Determinants for Lipid Transport and Protein Targeting at the Nucleus-Vacuole Junction
Structure, 25, 2017
5H2A
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Crystal structure of Osh1 ANK domain from Kluyveromyces lactis
分子名称: KLLA0C04147p
著者Im, Y.J, Manik, M.K, Yang, H.S, Tong, J.S.
登録日2016-10-14
公開日2017-05-10
最終更新日2024-03-20
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Structure of Yeast OSBP-Related Protein Osh1 Reveals Key Determinants for Lipid Transport and Protein Targeting at the Nucleus-Vacuole Junction
Structure, 25, 2017
5H28
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Crystal structure of Osh1 ANK domain from Saccharomyces cerevisia
分子名称: Oxysterol-binding protein homolog 1
著者Im, Y.J, Manik, M.K, Yang, H.S, Tong, J.S.
登録日2016-10-14
公開日2017-05-17
最終更新日2024-03-20
実験手法X-RAY DIFFRACTION (1.5 Å)
主引用文献Structure of Yeast OSBP-Related Protein Osh1 Reveals Key Determinants for Lipid Transport and Protein Targeting at the Nucleus-Vacuole Junction
Structure, 25, 2017
5VKQ
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Structure of a mechanotransduction ion channel Drosophila NOMPC in nanodisc
分子名称: 1,2-DIACYL-SN-GLYCERO-3-PHOSHOCHOLINE, No mechanoreceptor potential C isoform L
著者Jin, P, Bulkley, D, Guo, Y, Zhang, W, Guo, Z, Huynh, W, Wu, S, Meltzer, S, Chen, T, Jan, L.Y, Jan, Y.-N, Cheng, Y.
登録日2017-04-22
公開日2017-06-28
最終更新日2024-03-13
実験手法ELECTRON MICROSCOPY (3.55 Å)
主引用文献Electron cryo-microscopy structure of the mechanotransduction channel NOMPC.
Nature, 547, 2017
5GP7
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Structural basis for the binding between Tankyrase-1 and USP25
分子名称: GLYCEROL, Tankyrase-1, Ubiquitin carboxyl-terminal hydrolase 25
著者Liu, J, Xu, D, Fu, T, Pan, L.
登録日2016-08-01
公開日2017-07-12
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (1.502 Å)
主引用文献USP25 regulates Wnt signaling by controlling the stability of tankyrases
Genes Dev., 31, 2017
5Y4E
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Crystal Structure of AnkB Ankyrin Repeats R8-14 in complex with autoinhibition segment AI-b
分子名称: Ankyrin-2,Ankyrin-2, GLYCEROL, SULFATE ION
著者Chen, K, Li, J, Wang, C, Wei, Z, Zhang, M.
登録日2017-08-03
公開日2017-09-13
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (2.341 Å)
主引用文献Autoinhibition of ankyrin-B/G membrane target bindings by intrinsically disordered segments from the tail regions.
Elife, 6, 2017
5Y4D
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Crystal Structure of AnkB Ankyrin Repeats in Complex with AnkR/AnkB Chimeric Autoinhibition Segment
分子名称: Ankyrin-1,Ankyrin-2,Ankyrin-2, SULFATE ION
著者Chen, K, Li, J, Wang, C, Wei, Z, Zhang, M.
登録日2017-08-03
公開日2017-09-13
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (3.3 Å)
主引用文献Autoinhibition of ankyrin-B/G membrane target bindings by intrinsically disordered segments from the tail regions.
Elife, 6, 2017
5Y4F
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Crystal Structure of AnkB Ankyrin Repeats R13-24 in complex with autoinhibition segment AI-c
分子名称: ACETATE ION, Ankyrin-2, CALCIUM ION
著者Chen, K, Li, J, Wang, C, Wei, Z, Zhang, M.
登録日2017-08-03
公開日2017-09-13
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (1.953 Å)
主引用文献Autoinhibition of ankyrin-B/G membrane target bindings by intrinsically disordered segments from the tail regions.
Elife, 6, 2017
6EMK
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Cryo-EM Structure of Saccharomyces cerevisiae Target of Rapamycin Complex 2
分子名称: Serine/threonine-protein kinase TOR2, Target of rapamycin complex 2 subunit AVO1, Target of rapamycin complex 2 subunit AVO2, ...
著者Karuppasamy, M, Kusmider, B, Oliveira, T.M, Gaubitz, C, Prouteau, M, Loewith, R, Schaffitzel, C.
登録日2017-10-02
公開日2017-12-06
最終更新日2024-05-15
実験手法ELECTRON MICROSCOPY (7.9 Å)
主引用文献Cryo-EM structure of Saccharomyces cerevisiae target of rapamycin complex 2.
Nat Commun, 8, 2017
5YBJ
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Structure of apo KANK1 ankyrin domain
分子名称: GLYCEROL, KN motif and ankyrin repeat domain-containing protein 1
著者Guo, Q, Liao, S, Min, J, Xu, C, Structural Genomics Consortium (SGC)
登録日2017-09-05
公開日2017-12-06
最終更新日2024-03-27
実験手法X-RAY DIFFRACTION (2.341 Å)
主引用文献Structural basis for the recognition of kinesin family member 21A (KIF21A) by the ankyrin domains of KANK1 and KANK2 proteins.
J. Biol. Chem., 293, 2018

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