5GP7

Structural basis for the binding between Tankyrase-1 and USP25

Summary for 5GP7

• Entry DOI: 10.2210/pdb5gp7/pdb
• Descriptor: Tankyrase-1, Ubiquitin carboxyl-terminal hydrolase 25, GLYCEROL, ... (4 entities in total)
• Functional Keywords: tankyrase, usp25, ankyrin repeats, transferase
• Biological source: Homo sapiens (Human); More
• Cellular location: Cytoplasm: O95271; Cytoplasm . Isoform USP25m: Cytoplasm : Q9UHP3
• Total number of polymer chains: 2
• Total formula weight: 19394.84

Authors

Liu, J.,Xu, D.,Fu, T.,Pan, L. (deposition date: 2016-08-01, release date: 2017-07-12, Last modification date: 2023-11-08)

• Primary citation: Xu, D.,Liu, J.,Fu, T.,Shan, B.,Qian, L.,Pan, L.,Yuan, J.; USP25 regulates Wnt signaling by controlling the stability of tankyrases; Genes Dev., 31:1024-1035, 2017; PubMed: 28619731; DOI: 10.1101/gad.300889.117

Experimental method

X-RAY DIFFRACTION (1.502 Å)