PDB: 57 件ウェブページステータス検索Chemie searchBIRD

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6A5K	Crystal structure of Arabidopsis thaliana SUVH6 in complex with SAM, form 1 分子名称: Histone-lysine N-methyltransferase, H3 lysine-9 specific SUVH6, S-ADENOSYLMETHIONINE, ... 著者 Li, X, Du, J. 登録日 2018-06-24 公開日 2018-08-29 最終更新日 2018-09-26 実験手法 X-RAY DIFFRACTION (1.9 Å) 主引用文献 Mechanistic insights into plant SUVH family H3K9 methyltransferases and their binding to context-biased non-CG DNA methylation. Proc. Natl. Acad. Sci. U.S.A., 115, 2018
5YY9	Crystal structure of Tandem Tudor Domain of human UHRF1 in complex with LIG1-K126me3 分子名称: E3 ubiquitin-protein ligase UHRF1, Ligase 1 著者 Kori, S, Defossez, P.A, Arita, K. 登録日 2017-12-08 公開日 2018-12-12 最終更新日 2023-11-22 実験手法 X-RAY DIFFRACTION (2.653 Å) 主引用文献 Structure of the UHRF1 Tandem Tudor Domain Bound to a Methylated Non-histone Protein, LIG1, Reveals Rules for Binding and Regulation. Structure, 27, 2019
7XUD	Structure of G9a in complex with compound 26a 分子名称: 1,2-ETHANEDIOL, 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, CHLORIDE ION, ... 著者 Niwa, H, Shirai, F, Sato, S, Nishigaya, Y, Umehara, T. 登録日 2022-05-18 公開日 2023-03-29 最終更新日 2023-11-29 実験手法 X-RAY DIFFRACTION (1.45 Å) 主引用文献 Discovery of Novel Substrate-Competitive Lysine Methyltransferase G9a Inhibitors as Anticancer Agents. J.Med.Chem., 66, 2023
7XUA	Structure of G9a in complex with compound 10a 分子名称: 1,2-ETHANEDIOL, 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, Histone-lysine N-methyltransferase EHMT2, ... 著者 Niwa, H, Shirai, F, Sato, S, Nishigaya, Y, Umehara, T. 登録日 2022-05-18 公開日 2023-03-29 最終更新日 2023-11-29 実験手法 X-RAY DIFFRACTION (1.87 Å) 主引用文献 Discovery of Novel Substrate-Competitive Lysine Methyltransferase G9a Inhibitors as Anticancer Agents. J.Med.Chem., 66, 2023
7XUC	Structure of G9a in complex with compound 11a 分子名称: 1,2-ETHANEDIOL, 3,6,6-trimethyl-4-oxidanylidene-~{N}-[(2~{S})-1-oxidanylidene-1-phenylazanyl-hexan-2-yl]-5,7-dihydro-1~{H}-indole-2-carboxamide, CHLORIDE ION, ... 著者 Niwa, H, Shirai, F, Sato, S, Nishigaya, Y, Umehara, T. 登録日 2022-05-18 公開日 2023-03-29 最終更新日 2023-11-29 実験手法 X-RAY DIFFRACTION (1.67 Å) 主引用文献 Discovery of Novel Substrate-Competitive Lysine Methyltransferase G9a Inhibitors as Anticancer Agents. J.Med.Chem., 66, 2023
7XUB	Structure of G9a in complex with compound 10d 分子名称: 1,2-ETHANEDIOL, 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, Histone-lysine N-methyltransferase EHMT2, ... 著者 Niwa, H, Shirai, F, Sato, S, Nishigaya, Y, Umehara, T. 登録日 2022-05-18 公開日 2023-03-29 最終更新日 2023-11-29 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 Discovery of Novel Substrate-Competitive Lysine Methyltransferase G9a Inhibitors as Anticancer Agents. J.Med.Chem., 66, 2023
3K3N	Crystal structure of the catalytic core domain of human PHF8 分子名称: FE (II) ION, PHD finger protein 8 著者 Yu, L, Wang, Y, Huang, S, Wang, J, Deng, Z, Wu, W, Gong, W, Chen, Z. 登録日 2009-10-03 公開日 2010-01-19 最終更新日 2023-11-01 実験手法 X-RAY DIFFRACTION (2.4 Å) 主引用文献 Structural insights into a novel histone demethylase PHF8 Cell Res., 20, 2010

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