6D08

Crystal structure of an engineered bump-hole complex of mutant human chromobox homolog 1 (CBX1) with H3K9bn peptide

Summary for 6D08

Entry DOI	10.2210/pdb6d08/pdb
Descriptor	Chromobox protein homolog 1, Histone H3.1, GLYCEROL, ... (5 entities in total)
Functional Keywords	lysine modification, chromodomain, bump-hole, epigenetics, protein binding
Biological source	Homo sapiens (Human) More
Total number of polymer chains	4
Total formula weight	16646.63
Authors	Arora, S.,Horne, W.S.,Islam, K. (deposition date: 2018-04-10, release date: 2019-04-10, Last modification date: 2023-11-15)
Primary citation	Arora, S.,Horne, W.S.,Islam, K. Engineering Methyllysine Writers and Readers for Allele-Specific Regulation of Protein-Protein Interactions. J.Am.Chem.Soc., 141:15466-15470, 2019 Cited by PubMed: 31518125 DOI: 10.1021/jacs.9b05725 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.1 Å)

Structure validation