PDB: 19228 件ウェブページステータス検索Chemie searchBIRD

---

4XI2	Crystal Structure of an auto-inhibited form of Bruton's Tryrosine Kinase 分子名称: GOLD ION, Tyrosine-protein kinase BTK 著者 Vogan, E.M, Harrison, S.C. 登録日 2015-01-06 公開日 2015-02-25 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (2.6 Å) 主引用文献 Autoinhibition of Bruton's tyrosine kinase (Btk) and activation by soluble inositol hexakisphosphate. Elife, 4, 2015
6Q42	Crystal Structure of Human Pancreatic Phospholipase A2 分子名称: CHLORIDE ION, Phospholipase A2 著者 Saul, F, Haouz, A, Lambeau, G, Theze, J. 登録日 2018-12-05 公開日 2020-04-15 最終更新日 2024-01-24 実験手法 X-RAY DIFFRACTION (1.9 Å) 主引用文献 PLA2G1B is involved in CD4 anergy and CD4 lymphopenia in HIV-infected patients. J.Clin.Invest., 130, 2020
4S33	ERK2 R65S mutant complexed with AMP-PNP 分子名称: MAGNESIUM ION, Mitogen-activated protein kinase 1, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER, ... 著者 Livnah, O, Karamansha, Y, Tzarum, N. 登録日 2015-01-26 公開日 2016-01-27 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (1.48 Å) 主引用文献 Multiple mechanisms render Erk proteins MEK-independent To be Published
4TRX	HIGH-RESOLUTION THREE-DIMENSIONAL STRUCTURE OF REDUCED RECOMBINANT HUMAN THIOREDOXIN IN SOLUTION 分子名称: THIOREDOXIN 著者 Forman-Kay, J.D, Clore, G.M, Gronenborn, A.M. 登録日 1990-12-17 公開日 1992-01-15 最終更新日 2024-05-22 実験手法 SOLUTION NMR 主引用文献 High-resolution three-dimensional structure of reduced recombinant human thioredoxin in solution. Biochemistry, 30, 1991
6SZS	Release factor-dependent ribosome rescue by BrfA in the Gram-positive bacterium Bacillus subtilis 分子名称: 16S ribosomal RNA, 23S ribosomal RNA, 30S ribosomal protein S10, ... 著者 Muller, C, Beckert, B, Wilson, D.N. 登録日 2019-10-02 公開日 2019-12-04 最終更新日 2024-05-22 実験手法 ELECTRON MICROSCOPY (3.06 Å) 主引用文献 Release factor-dependent ribosome rescue by BrfA in the Gram-positive bacterium Bacillus subtilis. Nat Commun, 10, 2019
6QAL	ERK2 mini-fragment binding 分子名称: 1,1-bis(oxidanylidene)thietan-3-ol, Mitogen-activated protein kinase 1, SULFATE ION 著者 O'Reilly, M, Cleasby, A, Davies, T.G, Hall, R, Ludlow, F, Murray, C.W, Tisi, D, Jhoti, H. 登録日 2018-12-19 公開日 2019-03-27 最終更新日 2019-05-22 実験手法 X-RAY DIFFRACTION (1.57 Å) 主引用文献 Crystallographic screening using ultra-low-molecular-weight ligands to guide drug design. Drug Discov Today, 24, 2019
4XLN	Crystal structure of T. aquaticus transcription initiation complex containing bubble promoter and RNA 分子名称: DNA (48-MER), DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, ... 著者 Bae, B, Darst, S.A. 登録日 2015-01-13 公開日 2015-09-23 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (4 Å) 主引用文献 Structure of a bacterial RNA polymerase holoenzyme open promoter complex. Elife, 4, 2015
6QAW	ERK2 mini-fragment binding 分子名称: Mitogen-activated protein kinase 1, SULFATE ION, [1-(7~{H}-pyrrolo[2,3-d]pyrimidin-4-yl)piperidin-4-yl]methylazanium 著者 O'Reilly, M, Cleasby, A, Davies, T.G, Hall, R, Ludlow, F, Murray, C.W, Tisi, D, Jhoti, H. 登録日 2018-12-19 公開日 2019-03-27 最終更新日 2024-10-23 実験手法 X-RAY DIFFRACTION (1.84 Å) 主引用文献 Crystallographic screening using ultra-low-molecular-weight ligands to guide drug design. Drug Discov Today, 24, 2019
2MOX	solution structure of tandem SH3 domain of Sorbin and SH3 domain-containing protein 1 分子名称: Sorbin and SH3 domain-containing protein 1 著者 Zhao, D, Wang, C, Zhang, J, Wu, J, Shi, Y, Zhang, Z, Gong, Q. 登録日 2014-05-07 公開日 2014-05-28 最終更新日 2024-05-15 実験手法 SOLUTION NMR 主引用文献 Structural investigation of the interaction between the tandem SH3 domains of c-Cbl-associated protein and vinculin J.Struct.Biol., 187, 2014
4XP3	Crystal structure of ERK2 in complex with an inhibitor 分子名称: 2-amino-1,9-dihydro-6H-purine-6-thione, DIMETHYL SULFOXIDE, Mitogen-activated protein kinase 1, ... 著者 Gelin, M, Allemand, F, Labesse, G, Guichou, J.F. 登録日 2015-01-16 公開日 2015-08-12 最終更新日 2024-10-16 実験手法 X-RAY DIFFRACTION (1.782 Å) 主引用文献 Combining `dry' co-crystallization and in situ diffraction to facilitate ligand screening by X-ray crystallography. Acta Crystallogr.,Sect.D, 71, 2015
6PTN	Structure of Ctf4 trimer in complex with two CMG helicases 分子名称: ADENOSINE-5'-TRIPHOSPHATE, Cell division control protein 45, DNA polymerase alpha-binding protein, ... 著者 Yuan, Z, Georgescu, R, Bai, L, Santos, R, Donnell, M, Li, H. 登録日 2019-07-16 公開日 2019-11-20 最終更新日 2024-10-16 実験手法 ELECTRON MICROSCOPY (5.8 Å) 主引用文献 Ctf4 organizes sister replisomes and Pol alpha into a replication factory. Elife, 8, 2019
4XAX	Crystal structure of Thermus thermophilus CarD in complex with the Thermus aquaticus RNA polymerase beta1 domain 分子名称: 1,2-ETHANEDIOL, CarD, DNA-directed RNA polymerase subunit beta domain 1 著者 Chen, J, Bae, B, Campbell, E.A, Darst, S.A. 登録日 2014-12-15 公開日 2015-09-16 最終更新日 2023-09-27 実験手法 X-RAY DIFFRACTION (2.404 Å) 主引用文献 CarD uses a minor groove wedge mechanism to stabilize the RNA polymerase open promoter complex. Elife, 4, 2015
6QAQ	ERK2 mini-fragment binding 分子名称: Mitogen-activated protein kinase 1, SULFATE ION, thiophen-3-ylmethylazanium 著者 O'Reilly, M, Cleasby, A, Davies, T.G, Hall, R, Ludlow, F, Murray, C.W, Tisi, D, Jhoti, H. 登録日 2018-12-19 公開日 2019-03-27 最終更新日 2019-05-22 実験手法 X-RAY DIFFRACTION (1.58 Å) 主引用文献 Crystallographic screening using ultra-low-molecular-weight ligands to guide drug design. Drug Discov Today, 24, 2019
6Q98	Structure of tmRNA SmpB bound in P site of E. coli 70S ribosome 分子名称: 16S ribosomal RNA, 23S ribosomal RNA, 30S ribosomal protein S10, ... 著者 Rae, C.D. 登録日 2018-12-17 公開日 2019-02-27 最終更新日 2024-04-24 実験手法 ELECTRON MICROSCOPY (4.3 Å) 主引用文献 How a circularized tmRNA moves through the ribosome. Science, 363, 2019
4XJE	CRYSTAL STRUCTURE OF ANT(2") IN COMPLEX WITH AMP AND TOBRAMYCIN 分子名称: ADENOSINE MONOPHOSPHATE, AadB, GLYCEROL, ... 著者 Rodionov, D, Bassenden, A.V, Berghuis, A.M. 登録日 2015-01-08 公開日 2016-01-20 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (1.88 Å) 主引用文献 Revisiting the Catalytic Cycle and Kinetic Mechanism of AminoglycosideO-Nucleotidyltransferase(2′′): A Structural and Kinetic Study. Acs Chem.Biol., 2020
4V69	Ternary complex-bound E.coli 70S ribosome. 分子名称: 16S rRNA, 23S ribosomal RNA, 30S ribosomal protein S10, ... 著者 Villa, E, Sengupta, J, Trabuco, L.G, LeBarron, J, Baxter, W.T, Shaikh, T.R, Grassucci, R.A, Nissen, P, Ehrenberg, M, Schulten, K, Frank, J. 登録日 2008-12-11 公開日 2014-07-09 最終更新日 2024-02-28 実験手法 ELECTRON MICROSCOPY (6.7 Å) 主引用文献 Ribosome-induced changes in elongation factor Tu conformation control GTP hydrolysis Proc.Natl.Acad.Sci.USA, 106, 2009
4U0R	Plasmodium falciparum reticulocyte-binding protein homologue 5 (PfRH5) bound to monoclonal antibody 9AD4 分子名称: Monoclonal antibody 9AD4 heavy chain, Monoclonal antibody 9AD4 light chain, Reticulocyte binding protein 5 著者 Wright, K.E, Hjerrild, K.A, Bartlett, J, Douglas, A.D, Jin, J, Brown, R.E, Ashfield, R, Clemmensen, S.B, de Jongh, W.A, Draper, S.J, Higgins, M.K. 登録日 2014-07-14 公開日 2014-08-13 最終更新日 2024-10-16 実験手法 X-RAY DIFFRACTION (2.3 Å) 主引用文献 Structure of malaria invasion protein RH5 with erythrocyte basigin and blocking antibodies. Nature, 515, 2014
4V6O	Structural characterization of mRNA-tRNA translocation intermediates (class 4a of the six classes) 分子名称: 16S ribosomal RNA, 23S ribosomal RNA, 30S ribosomal protein S10, ... 著者 Agirrezabala, X, Liao, H, Schreiner, E, Fu, J, Ortiz-Meoz, R.F, Schulten, K, Green, R, Frank, J. 登録日 2011-12-07 公開日 2014-07-09 最終更新日 2024-05-15 実験手法 ELECTRON MICROSCOPY (14.7 Å) 主引用文献 Structural characterization of mRNA-tRNA translocation intermediates. Proc.Natl.Acad.Sci.USA, 109, 2012
4V70	E. coli 70S-fMetVal-tRNAVal-tRNAfMet complex in intermediate pre-translocation state (pre3) 分子名称: 16S ribosomal RNA, 23S ribosomal RNA, 30S ribosomal protein S10, ... 著者 Blau, C, Bock, L.V, Schroder, G.F, Davydov, I, Fischer, N, Stark, H, Rodnina, M.V, Vaiana, A.C, Grubmuller, H. 登録日 2013-10-14 公開日 2014-07-09 最終更新日 2019-12-18 実験手法 ELECTRON MICROSCOPY (17 Å) 主引用文献 Energy barriers and driving forces in tRNA translocation through the ribosome. Nat.Struct.Mol.Biol., 20, 2013
4U27	Crystal structure of the E. coli ribosome bound to flopristin and linopristin. 分子名称: 16S rRNA, 23S rRNA, 30S ribosomal protein S10, ... 著者 Noeske, J, Huang, J, Olivier, N.B, Giacobbe, R.A, Zambrowski, M, Cate, J.H.D. 登録日 2014-07-16 公開日 2014-07-30 最終更新日 2024-10-09 実験手法 X-RAY DIFFRACTION (2.8 Å) 主引用文献 Synergy of streptogramin antibiotics occurs independently of their effects on translation. Antimicrob.Agents Chemother., 58, 2014
4V6A	Structure of EF-P bound to the 70S ribosome. 分子名称: 16S ribosomal RNA, 23S ribosomal RNA, 30S ribosomal protein S10, ... 著者 Stanley, R.E, Blaha, G. 登録日 2009-06-15 公開日 2014-07-09 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (3.1 Å) 主引用文献 Formation of the first peptide bond: the structure of EF-P bound to the 70S ribosome. Science, 325, 2009
4V6Z	E. coli 70S-fMetVal-tRNAVal-tRNAfMet complex in classic pre-translocation state (pre1b) 分子名称: 16S ribosomal RNA, 23S ribosomal RNA, 30S ribosomal protein S10, ... 著者 Blau, C, Bock, L.V, Schroder, G.F, Davydov, I, Fischer, N, Stark, H, Rodnina, M.V, Vaiana, A.C, Grubmuller, H. 登録日 2013-10-14 公開日 2014-07-09 最終更新日 2024-10-30 実験手法 ELECTRON MICROSCOPY (12 Å) 主引用文献 Energy barriers and driving forces in tRNA translocation through the ribosome. Nat.Struct.Mol.Biol., 20, 2013
4V6M	Structure of the ribosome-SecYE complex in the membrane environment 分子名称: (1R)-2-{[{[(2S)-2,3-DIHYDROXYPROPYL]OXY}(HYDROXY)PHOSPHORYL]OXY}-1-[(PALMITOYLOXY)METHYL]ETHYL (11E)-OCTADEC-11-ENOATE, (1S)-2-{[(2-AMINOETHOXY)(HYDROXY)PHOSPHORYL]OXY}-1-[(PALMITOYLOXY)METHYL]ETHYL STEARATE, 16S RIBOSOMAL RNA, ... 著者 Frauenfeld, J, Gumbart, J, van der Sluis, E.O, Funes, S, Gartmann, M, Beatrix, B, Mielke, T, Berninghausen, O, Becker, T, Schulten, K, Beckmann, R. 登録日 2011-02-08 公開日 2014-07-09 最終更新日 2024-02-28 実験手法 ELECTRON MICROSCOPY (7.1 Å) 主引用文献 Cryo-EM structure of the ribosome-SecYE complex in the membrane environment. Nat.Struct.Mol.Biol., 18, 2011
4V7D	Structure of the Ribosome with Elongation Factor G Trapped in the Pre-Translocation State (pre-translocation 70S*tRNA*EF-G structure) 分子名称: 16S ribosomal RNA, 23S ribosomal RNA, 30S ribosomal protein S10, ... 著者 Brilot, A.F, Korostelev, A.A, Ermolenko, D.N, Grigorieff, N. 登録日 2013-11-21 公開日 2014-07-09 最終更新日 2019-12-18 実験手法 ELECTRON MICROSCOPY (7.6 Å) 主引用文献 Structure of the ribosome with elongation factor G trapped in the pretranslocation state. Proc.Natl.Acad.Sci.USA, 110, 2013
4X9Z	Dimeric conotoxin alphaD-GeXXA 分子名称: alphaD-conotoxin GeXXA from the venom of Conus generalis 著者 Xu, S, Zhang, T, Kompella, S, Adams, D, Ding, J, Wang, C. 登録日 2014-12-12 公開日 2015-12-02 最終更新日 2020-02-05 実験手法 X-RAY DIFFRACTION (1.5 Å) 主引用文献 Conotoxin alpha D-GeXXA utilizes a novel strategy to antagonize nicotinic acetylcholine receptors Sci Rep, 5, 2015

<290291292293294295296297298299300301302303304305>