4U0R

Plasmodium falciparum reticulocyte-binding protein homologue 5 (PfRH5) bound to monoclonal antibody 9AD4

Summary for 4U0R

Entry DOI	10.2210/pdb4u0r/pdb
Descriptor	Reticulocyte binding protein 5, Monoclonal antibody 9AD4 heavy chain, Monoclonal antibody 9AD4 light chain, ... (4 entities in total)
Functional Keywords	malaria erythrocyte invasion antibody-mediated inhibition, immune system
Biological source	Plasmodium falciparum More
Total number of polymer chains	3
Total formula weight	117029.30
Authors	Wright, K.E.,Hjerrild, K.A.,Bartlett, J.,Douglas, A.D.,Jin, J.,Brown, R.E.,Ashfield, R.,Clemmensen, S.B.,de Jongh, W.A.,Draper, S.J.,Higgins, M.K. (deposition date: 2014-07-14, release date: 2014-08-13, Last modification date: 2023-12-20)
Primary citation	Wright, K.E.,Hjerrild, K.A.,Bartlett, J.,Douglas, A.D.,Jin, J.,Brown, R.E.,Illingworth, J.J.,Ashfield, R.,Clemmensen, S.B.,de Jongh, W.A.,Draper, S.J.,Higgins, M.K. Structure of malaria invasion protein RH5 with erythrocyte basigin and blocking antibodies. Nature, 515:427-430, 2014 Cited by PubMed: 25132548 DOI: 10.1038/nature13715 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.3 Å)

Structure validation