PDB: 71589 件ウェブページステータス検索Chemie searchBIRD

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5WB8	Crystal structure of the epidermal growth factor receptor extracellular region in complex with epigen 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Epidermal growth factor receptor, Epigen, ... 著者 Bessman, N.J, Freed, D.M, Moore, J.O, Ferguson, K.M, Lemmon, M.A. 登録日 2017-06-28 公開日 2017-10-18 最終更新日 2023-10-04 実験手法 X-RAY DIFFRACTION (3 Å) 主引用文献 EGFR Ligands Differentially Stabilize Receptor Dimers to Specify Signaling Kinetics. Cell, 171, 2017
1NYH	Crystal Structure of the Coiled-coil Dimerization Motif of Sir4 分子名称: Regulatory protein SIR4 著者 Chang, J.F, Hall, B.E, Tanny, J.C, Moazed, D, Filman, D, Ellenberger, T. 登録日 2003-02-12 公開日 2003-06-24 最終更新日 2024-02-14 実験手法 X-RAY DIFFRACTION (3.1 Å) 主引用文献 Structure of the Coiled-coil Dimerization Motif of Sir4 and Its Interaction With Sir3 Structure, 11, 2003
5WEW	Crystal structure of Klebsiella pneumoniae fosfomycin resistance protein (FosAKP) with inhibitor (ANY1) bound 分子名称: 6,6'-(4-nitro-1H-pyrazole-3,5-diyl)bis(3-bromopyrazolo[1,5-a]pyrimidin-2(1H)-one), Fosfomycin resistance protein, MANGANESE (II) ION 著者 Klontz, E.H, Sundberg, E.J. 登録日 2017-07-10 公開日 2018-07-18 最終更新日 2023-10-04 実験手法 X-RAY DIFFRACTION (3.178 Å) 主引用文献 Small-Molecule Inhibitor of FosA Expands Fosfomycin Activity to Multidrug-Resistant Gram-Negative Pathogens. Antimicrob. Agents Chemother., 63, 2019
1YY9	Structure of the extracellular domain of the epidermal growth factor receptor in complex with the Fab fragment of cetuximab/Erbitux/IMC-C225 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Cetuximab Fab Heavy chain, ... 著者 Li, S, Schmitz, K.R, Jeffrey, P.D, Wiltzius, J.J.W, Kussie, P, Ferguson, K.M. 登録日 2005-02-24 公開日 2005-04-26 最終更新日 2023-08-23 実験手法 X-RAY DIFFRACTION (2.605 Å) 主引用文献 Structural basis for inhibition of the epidermal growth factor receptor by cetuximab Cancer Cell, 7, 2005
7VKE	Crystal structure of human CD38 ECD in complex with UniDab(TM) F11A 分子名称: 1,2-ETHANEDIOL, ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 1, CHLORIDE ION, ... 著者 Schooten, W.V, Schellenberger, U, Ugamraj, H.S, Manicka, S, Bijpuria, S, Gondu, R.K. 登録日 2021-09-29 公開日 2022-08-03 最終更新日 2023-11-29 実験手法 X-RAY DIFFRACTION (1.9 Å) 主引用文献 TNB-738, a biparatopic antibody, boosts intracellular NAD+ by inhibiting CD38 ecto-enzyme activity. Mabs, 14, 2022
1NMN	Structure of yqgF from Escherichia coli, a hypothetical protein 分子名称: Hypothetical protein yqgF 著者 Galkin, A, Sarikaya, E, Krajewski, W, Howard, A, Herzberg, O, Structure 2 Function Project (S2F) 登録日 2003-01-10 公開日 2004-03-02 最終更新日 2024-02-14 実験手法 X-RAY DIFFRACTION (2.3 Å) 主引用文献 Structure of yqgF from Escherichia coli, a hypothetical protein To be Published
1ZO1	IF2, IF1, and tRNA fitted to cryo-EM data OF E. COLI 70S initiation complex 分子名称: P/I-site tRNA, translation Initiation Factor 1, translation initiation factor 2 著者 Allen, G.S, Zavialov, A, Gursky, R, Ehrenberg, M, Frank, J. 登録日 2005-05-12 公開日 2005-06-14 最終更新日 2024-02-14 実験手法 ELECTRON MICROSCOPY (13.8 Å) 主引用文献 The Cryo-EM Structure of a Translation Initiation Complex from Escherichia coli. Cell(Cambridge,Mass.), 121, 2005
1Z1B	Crystal structure of a lambda integrase dimer bound to a COC' core site 分子名称: 26-MER DNA, 29-MER DNA, 5'-D(*CP*T*CP*GP*TP*TP*CP*AP*GP*CP*TP*TP*TP*TP*TP*T)-3', ... 著者 Biswas, T, Aihara, H, Radman-Livaja, M, Filman, D, Landy, A, Ellenberger, T. 登録日 2005-03-03 公開日 2005-06-28 最終更新日 2022-04-13 実験手法 X-RAY DIFFRACTION (3.8 Å) 主引用文献 A structural basis for allosteric control of DNA recombination by lambda integrase. Nature, 435, 2005
6YUR	Crystal structure of S. aureus FabI inhibited by SKTS1 分子名称: 6-[4-(4-hexyl-2-oxidanyl-phenoxy)phenoxy]pyridin-2-ol, Enoyl-[acyl-carrier-protein] reductase [NADPH], NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE 著者 Weinrich, J.D, Eltschkner, S, Schiebel, J, Kehrein, J, Le, T.A, Davoodi, S, Merget, B, Tonge, P.J, Engels, B, Sotriffer, C.A, Kisker, C. 登録日 2020-04-27 公開日 2021-03-24 最終更新日 2024-01-24 実験手法 X-RAY DIFFRACTION (1.96 Å) 主引用文献 A Long Residence Time Enoyl-Reductase Inhibitor Explores an Extended Binding Region with Isoenzyme-Dependent Tautomer Adaptation and Differential Substrate-Binding Loop Closure. Acs Infect Dis., 7, 2021
6YUU	Crystal structure of M. tuberculosis InhA inhibited by SKTS1 分子名称: 6-[4-(4-hexyl-2-oxidanyl-phenoxy)phenoxy]pyridin-2-ol, CHLORIDE ION, Enoyl-[acyl-carrier-protein] reductase [NADH], ... 著者 Eltschkner, S, Schiebel, J, Kehrein, J, Le, T.A, Davoodi, S, Merget, B, Weinrich, J.D, Tonge, P.J, Engels, B, Sotriffer, C.A, Kisker, C. 登録日 2020-04-27 公開日 2021-03-24 最終更新日 2024-01-24 実験手法 X-RAY DIFFRACTION (2.01 Å) 主引用文献 A Long Residence Time Enoyl-Reductase Inhibitor Explores an Extended Binding Region with Isoenzyme-Dependent Tautomer Adaptation and Differential Substrate-Binding Loop Closure. Acs Infect Dis., 7, 2021
5WK6	Cryo-EM structure of P. aeruginosa flagellar filaments G420A 分子名称: B-type flagellin 著者 Wang, F, Postel, S, Sundberg, E.J, Egelman, E.H. 登録日 2017-07-24 公開日 2017-10-25 最終更新日 2024-03-13 実験手法 ELECTRON MICROSCOPY (4.3 Å) 主引用文献 A structural model of flagellar filament switching across multiple bacterial species. Nat Commun, 8, 2017
1Z6P	Glycogen phosphorylase AMP site inhibitor complex 分子名称: 4-{2-[(3-NITROBENZOYL)AMINO]PHENOXY}PHTHALIC ACID, Glycogen phosphorylase, muscle form 著者 Kristiansen, M, Andersen, B, Iversen, L.F, Westergaard, N. 登録日 2005-03-23 公開日 2005-04-12 最終更新日 2011-07-13 実験手法 X-RAY DIFFRACTION (2.4 Å) 主引用文献 Identification, synthesis and chracterization of new glycogen phosphorylase inhibitors binding to the allosteric AMP site J.Med.Chem., 47, 2004
2VDC	THE 9.5 A RESOLUTION STRUCTURE OF GLUTAMATE SYNTHASE FROM CRYO-ELECTRON MICROSCOPY AND ITS OLIGOMERIZATION BEHAVIOR IN SOLUTION: FUNCTIONAL IMPLICATIONS. 分子名称: 2-OXOGLUTARIC ACID, FE3-S4 CLUSTER, FLAVIN MONONUCLEOTIDE, ... 著者 Cottevieille, M, Larquet, E, Jonic, S, Petoukhov, M.V, Caprini, G, Paravisi, S, Svergun, D.I, Vanoni, M.A, Boisset, N. 登録日 2007-10-04 公開日 2008-01-15 最終更新日 2024-05-08 実験手法 ELECTRON MICROSCOPY (9.5 Å) 主引用文献 The Subnanometer Resolution Structure of the Glutamate Synthase 1.2-Mda Hexamer by Cryoelectron Microscopy and its Oligomerization Behavior in Solution: Functional Implications. J.Biol.Chem., 283, 2008
1NTH	Crystal structure of the methanosarcina barkeri monomethylamine methyltransferase (MTMB) 分子名称: Monomethylamine methyltransferase mtmB1 著者 Hao, B, Gong, W, Ferguson, T.K, James, C.M, Krzycki, J.A, Chan, M.K. 登録日 2003-01-30 公開日 2003-02-04 最終更新日 2024-02-14 実験手法 X-RAY DIFFRACTION (1.55 Å) 主引用文献 A new UAG-encoded residue in the structure of a methanogen methyltransferase Science, 296, 2002
6Z0S	Allostery through DNA drives phenotype switching 分子名称: comG promoter DNA - strand A, comG promoter DNA - strand B 著者 Rosenblum, G, Elad, N, Rozenberg, H, Wiggers, F, Jungwirth, J, Hofmann, H. 登録日 2020-05-11 公開日 2021-04-07 最終更新日 2024-05-22 実験手法 ELECTRON MICROSCOPY (5.7 Å) 主引用文献 Allostery through DNA drives phenotype switching. Nat Commun, 12, 2021
2VLK	The Structural Dynamics and Energetics of an Immunodominant T-cell Receptor are Programmed by its Vbeta Domain 分子名称: BETA-2-MICROGLOBULIN, FLU MATRIX PEPTIDE, HLA CLASS I HISTOCOMPATIBILITY ANTIGEN, ... 著者 Ishizuka, J, Stewart-Jones, G, Van Der Merwe, A, Bell, J, Mcmichael, A, Jones, Y. 登録日 2008-01-15 公開日 2008-01-22 最終更新日 2011-07-13 実験手法 X-RAY DIFFRACTION (2.5 Å) 主引用文献 The Structural Dynamics and Energetics of an Immunodominant T-Cell Receptor are Programmed by its Vbeta Domain Immunity, 28, 2008
1X6J	Crystal structure of ygfY from Escherichia coli 分子名称: Hypothetical protein ygfY 著者 Lim, K, Doseeva, V, Sarikaya Demirkan, E, Pullalarevu, S, Krajewski, W, Galkin, A, Howard, A, Herzberg, O, Structure 2 Function Project (S2F) 登録日 2004-08-11 公開日 2005-02-08 最終更新日 2024-02-14 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 Crystal structure of the YgfY from Escherichia coli, a protein that may be involved in transcriptional regulation Proteins, 58, 2005
2VLM	The Structural Dynamics and Energetics of an Immunodominant T-cell Receptor are Programmed by its Vbeta Domain 分子名称: JM22 TCR ALPHA CHAIN, JM22 TCR BETA CHAIN 著者 Ishizuka, J, Stewart-Jones, G, Van der Merwe, A, Bell, J, McMichael, A, Jones, Y. 登録日 2008-01-15 公開日 2008-01-22 最終更新日 2011-07-13 実験手法 X-RAY DIFFRACTION (1.98 Å) 主引用文献 The Structural Dynamics and Energetics of an Immunodominant T-Cell Receptor are Programmed by its Vbeta Domain Immunity, 28, 2008
2OT5	Crystal structure of the HIV gp41 core with the enfuvirtide resistance mutation N43D 分子名称: HIV-1 gp41 glycoprotein 著者 Bai, X, Seedorff, J.E, Green, J, Dwyer, J.J. 登録日 2007-02-07 公開日 2008-06-17 最終更新日 2023-08-30 実験手法 X-RAY DIFFRACTION (1.8 Å) 主引用文献 Impact of the enfuvirtide resistance mutation N43D and the associated baseline polymorphism E137K on peptide sensitivity and six-helix bundle structure. Biochemistry, 47, 2008
1X81	Farnesyl transferase structure of Jansen compound 分子名称: 6-[(S)-AMINO(4-CHLOROPHENYL)(1-METHYL-1H-IMIDAZOL-5-YL)METHYL]-4-(3-CHLOROPHENYL)-1-METHYLQUINOLIN-2(1H)-ONE, Protein farnesyltransferase beta subunit, Protein farnesyltransferase/geranylgeranyltransferase type I alpha subunit, ... 著者 Li, Q, Claiborne, A, Li, T, Hasvold, L, Stoll, V.S, Muchmore, S, Jakob, C.G, Gu, W, Cohen, J, Hutchins, C, Frost, D, Rosenberg, S.H, Sham, H.L. 登録日 2004-08-16 公開日 2004-12-21 最終更新日 2024-02-14 実験手法 X-RAY DIFFRACTION (3.5 Å) 主引用文献 Design, synthesis, and activity of 4-quinolone and pyridone compounds as nonthiol-containing farnesyltransferase inhibitors. Bioorg.Med.Chem.Lett., 14, 2004
2VBM	Tailspike protein of bacteriophage Sf6 complexed with tetrasaccharide 分子名称: MAGNESIUM ION, MANGANESE (II) ION, PHOSPHATE ION, ... 著者 Mueller, J.J, Barbirz, S, Freiberg, A, Seckler, R, Heinemann, U. 登録日 2007-09-14 公開日 2008-04-22 最終更新日 2023-12-13 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 An Intersubunit Active Site between Supercoiled Parallel Beta Helices in the Trimeric Tailspike Endorhamnosidase of Shigella Flexneri Phage Sf6. Structure, 16, 2008
2VAZ	Model of the S15-mRNA complex fitted into the cryo-EM map of the 70S entrapment complex. 分子名称: 30S RIBOSOMAL PROTEIN S15, RPSO MRNA OPERATOR 著者 Marzi, S, Myasnikov, A.G, Serganov, A, Ehresmann, C, Romby, P, Yusupov, M, Klaholz, B.P. 登録日 2007-09-05 公開日 2007-10-02 最終更新日 2024-05-08 実験手法 ELECTRON MICROSCOPY (10 Å) 主引用文献 Structured Mrnas Regulate Translation Initiation by Binding to the Platform of the Ribosome. Cell(Cambridge,Mass.), 130, 2007
1X9W	T7 DNA polymerase in complex with a primer/template DNA containing a disordered N-2 aminofluorene on the template, crystallized with dideoxy-ATP as the incoming nucleotide. 分子名称: 5'-D(*CP*CP*CP*(AFG)*AP*TP*CP*AP*CP*AP*CP*TP*AP*CP*CP*AP*AP*TP*CP*AP*CP*TP*CP*TP*CP*C)-3', 5'-D(*GP*GP*AP*GP*AP*GP*TP*GP*AP*TP*T*GP*GP*T*AP*GP*TP*GP*TP*GP*AP*(2DT))-3', DNA polymerase, ... 著者 Dutta, S, Li, Y, Johnson, D, Dzantiev, L, Richardson, C.C, Romano, L.J, Ellenberger, T. 登録日 2004-08-24 公開日 2004-10-26 最終更新日 2024-02-14 実験手法 X-RAY DIFFRACTION (2.3 Å) 主引用文献 Crystal structures of 2-acetylaminofluorene and 2-aminofluorene in complex with T7 DNA polymerase reveal mechanisms of mutagenesis. Proc.Natl.Acad.Sci.Usa, 101, 2004
3JC9	Architectural model of the type IVa pilus machine in a non-piliated state 分子名称: ADENOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, PilA, ... 著者 Chang, Y.-W, Rettberg, L.A, Jensen, G.J. 登録日 2015-11-24 公開日 2016-03-16 最終更新日 2018-07-18 実験手法 ELECTRON MICROSCOPY 主引用文献 Architecture of the type IVa pilus machine. Science, 351, 2016
8BFZ	Amyloid-beta 42 filaments extracted from the human brain with Arctic mutation (E22G) of Alzheimer's disease | ABeta42 分子名称: Amyloid-beta precursor protein 著者 Yang, Y, Zhang, W.J, Murzin, A.G, Schweighauser, M, Huang, M, Lovestam, S.K.A, Peak-Chew, S.Y, Macdonald, J, Lavenir, I, Ghetti, B, Graff, C, Kumar, A, Nordberg, A, Goedert, M, Scheres, S.H.W. 登録日 2022-10-27 公開日 2023-01-18 最終更新日 2024-01-31 実験手法 ELECTRON MICROSCOPY (2.8 Å) 主引用文献 Cryo-EM structures of amyloid-beta filaments with the Arctic mutation (E22G) from human and mouse brains. Acta Neuropathol, 145, 2023

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