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PDB: 7 results
1YCQ
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BU of 1ycq by Molmil
XENOPUS LAEVIS MDM2 BOUND TO THE TRANSACTIVATION DOMAIN OF HUMAN P53
Descriptor: MDM2, P53
Authors:Kussie, P.H, Pavletich, N.P.
Deposit date:1996-09-30
Release date:1997-11-19
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Structure of the MDM2 oncoprotein bound to the p53 tumor suppressor transactivation domain.
Science, 274, 1996
1YCR
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BU of 1ycr by Molmil
MDM2 BOUND TO THE TRANSACTIVATION DOMAIN OF P53
Descriptor: MDM2, P53
Authors:Kussie, P.H, Pavletich, N.P.
Deposit date:1996-09-30
Release date:1997-11-19
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Structure of the MDM2 oncoprotein bound to the p53 tumor suppressor transactivation domain.
Science, 274, 1996
1A41
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BU of 1a41 by Molmil
TYPE 1-TOPOISOMERASE CATALYTIC FRAGMENT FROM VACCINIA VIRUS
Descriptor: SULFATE ION, TOPOISOMERASE I
Authors:Cheng, C, Kussie, P, Pavletich, N, Shuman, S.
Deposit date:1998-02-10
Release date:1999-06-01
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Conservation of structure and mechanism between eukaryotic topoisomerase I and site-specific recombinases.
Cell(Cambridge,Mass.), 92, 1998
3B2U
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BU of 3b2u by Molmil
Crystal structure of isolated domain III of the extracellular region of the epidermal growth factor receptor in complex with the Fab fragment of IMC-11F8
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Epidermal growth factor receptor, ...
Authors:Ferguson, K.M, Li, S, Kussie, P.
Deposit date:2007-10-19
Release date:2008-02-19
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (2.58 Å)
Cite:Structural basis for EGF receptor inhibition by the therapeutic antibody IMC-11F8.
Structure, 16, 2008
1YY8
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BU of 1yy8 by Molmil
Crystal structure of the Fab fragment from the monoclonal antibody cetuximab/Erbitux/IMC-C225
Descriptor: Cetuximab Fab Heavy chain, Cetuximab Fab Light chain
Authors:Li, S, Schmitz, K.R, Jeffrey, P.D, Wiltzius, J.J.W, Kussie, P, Ferguson, K.M.
Deposit date:2005-02-24
Release date:2005-04-26
Last modified:2023-08-23
Method:X-RAY DIFFRACTION (2 Å)
Cite:Structural basis for inhibition of the epidermal growth factor receptor by cetuximab
Cancer Cell, 7, 2005
1YY9
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BU of 1yy9 by Molmil
Structure of the extracellular domain of the epidermal growth factor receptor in complex with the Fab fragment of cetuximab/Erbitux/IMC-C225
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Cetuximab Fab Heavy chain, ...
Authors:Li, S, Schmitz, K.R, Jeffrey, P.D, Wiltzius, J.J.W, Kussie, P, Ferguson, K.M.
Deposit date:2005-02-24
Release date:2005-04-26
Last modified:2023-08-23
Method:X-RAY DIFFRACTION (2.605 Å)
Cite:Structural basis for inhibition of the epidermal growth factor receptor by cetuximab
Cancer Cell, 7, 2005
3B2V
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BU of 3b2v by Molmil
Crystal structure of the extracellular region of the epidermal growth factor receptor in complex with the Fab fragment of IMC-11F8
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Epidermal growth factor receptor, ...
Authors:Ferguson, K.M, Li, S, Kussie, P.
Deposit date:2007-10-19
Release date:2008-02-19
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (3.3 Å)
Cite:Structural basis for EGF receptor inhibition by the therapeutic antibody IMC-11F8.
Structure, 16, 2008

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