PDB: 8717 件ウェブページステータス検索Chemie searchBIRD

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6SQI	Crystal structure of mouse PRMT6 with C-terminal TEV cleavage site 分子名称: CALCIUM ION, Protein arginine N-methyltransferase 6 著者 Bonnefond, L, Cavarelli, J. 登録日 2019-09-04 公開日 2020-09-30 最終更新日 2024-01-24 実験手法 X-RAY DIFFRACTION (1.6 Å) 主引用文献 Crystal structure of mouse PRMT6 in complex with inhibitors To Be Published
7BMC	Crystal structure of 14-3-3 sigma in complex with CIP2ApS904 peptide and stabilizing Fusicoccin A 分子名称: 14-3-3 protein sigma, CHLORIDE ION, FUSICOCCIN, ... 著者 Centorrino, F, Andlovic, B, Ottmann, C. 登録日 2021-01-19 公開日 2022-03-02 最終更新日 2024-01-31 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 Fusicoccin-A Targets Cancerous Inhibitor of Protein Phosphatase 2A by Stabilizing a C-Terminal Interaction with 14-3-3. Acs Chem.Biol., 17, 2022
7BM9	Crystal structure of 14-3-3 sigma in complex with CIP2ApS904 peptide 分子名称: 14-3-3 protein sigma, CHLORIDE ION, MAGNESIUM ION, ... 著者 Centorrino, F, Andlovic, B, Ottmann, C. 登録日 2021-01-19 公開日 2022-03-02 最終更新日 2024-01-31 実験手法 X-RAY DIFFRACTION (1.8 Å) 主引用文献 Fusicoccin-A Targets Cancerous Inhibitor of Protein Phosphatase 2A by Stabilizing a C-Terminal Interaction with 14-3-3. Acs Chem.Biol., 17, 2022
6TA2	Human NAMPT in complex with nicotinic acid mononucleotide and phosphate 分子名称: CHLORIDE ION, GLYCEROL, NICOTINATE MONONUCLEOTIDE, ... 著者 Houry, D, Raasakka, A, Kursula, P, Ziegler, M. 登録日 2019-10-29 公開日 2020-11-18 最終更新日 2024-01-24 実験手法 X-RAY DIFFRACTION (1.68 Å) 主引用文献 Identification of structural determinants of NAMPT activity and substrate selectivity To Be Published
8Q5H	Human KMN network (outer kinetochore) 分子名称: Kinetochore protein Spc24, Kinetochore protein Spc25, Kinetochore scaffold 1, ... 著者 Raisch, T, Polley, S, Vetter, I, Musacchio, A, Raunser, S. 登録日 2023-08-09 公開日 2024-02-14 実験手法 ELECTRON MICROSCOPY (4.5 Å) 主引用文献 Insights into human outer kinetochore assembly and force transmission from a structure-function analysis of the KMN network To Be Published
6T5F	Human 14-3-3 sigma fused to the StARD1 peptide including phosphoserine-195 分子名称: 14-3-3 protein sigma, StARD1 peptide 著者 Sluchanko, N.N, Tugaeva, K.V, Titterington, J, Antson, A.A. 登録日 2019-10-16 公開日 2020-11-18 最終更新日 2024-01-24 実験手法 X-RAY DIFFRACTION (2.63 Å) 主引用文献 Molecular basis for the recognition of steroidogenic acute regulatory protein by the 14-3-3 protein family. Febs J., 287, 2020
6TAC	Human NAMPT deletion mutant in complex with nicotinamide mononucleotide, pyrophosphate, and Mg2+ 分子名称: BETA-NICOTINAMIDE RIBOSE MONOPHOSPHATE, GLYCEROL, MAGNESIUM ION, ... 著者 Houry, D, Raasakka, A, Kursula, P, Ziegler, M. 登録日 2019-10-29 公開日 2020-11-18 最終更新日 2024-01-24 実験手法 X-RAY DIFFRACTION (1.6 Å) 主引用文献 Identification of structural determinants of NAMPT activity and substrate selectivity To Be Published
5U5S	Solution structures of Brd2 second bromodomain in complex with stat3 peptide 分子名称: Bromodomain-containing protein 2, Stat3 peptide 著者 Zeng, L, Zhou, M.-M. 登録日 2016-12-07 公開日 2017-03-22 最終更新日 2023-11-15 実験手法 SOLUTION NMR 主引用文献 Distinct Roles of Brd2 and Brd4 in Potentiating the Transcriptional Program for Th17 Cell Differentiation. Mol. Cell, 65, 2017
8Q7E	Structure of CUL9-RBX1 ubiquitin E3 ligase complex - hexameric assembly 分子名称: Cullin-9, E3 ubiquitin-protein ligase RBX1 著者 Hopf, L.V.M, Horn-Ghetko, D, Schulman, B.A. 登録日 2023-08-16 公開日 2024-04-17 最終更新日 2024-07-31 実験手法 ELECTRON MICROSCOPY (4.4 Å) 主引用文献 Noncanonical assembly, neddylation and chimeric cullin-RING/RBR ubiquitylation by the 1.8 MDa CUL9 E3 ligase complex. Nat.Struct.Mol.Biol., 31, 2024
8IK5	Transcription factor LMX1a homeobox domain in complex with Wnt1 promoter 分子名称: DNA (5'-D(*CP*CP*AP*TP*AP*TP*TP*TP*AP*AP*TP*CP*TP*TP*C)-3'), DNA (5'-D(*GP*GP*AP*AP*GP*AP*TP*TP*AP*AP*AP*TP*AP*TP*G)-3'), GLYCEROL, ... 著者 Lv, M.Q, Lin, L.Q. 登録日 2023-02-28 公開日 2024-03-06 実験手法 X-RAY DIFFRACTION (1.989 Å) 主引用文献 Structural insights into the recognition of the A/T-rich motif in target gene promoters by the LMX1a homeobox domain Febs J., 2024
8ILW	Transcription factor LMX1a homeobox domain in complex with Pitx3 promoter 分子名称: DNA (5'-D(*CP*AP*AP*CP*AP*CP*TP*TP*AP*AP*TP*CP*CP*AP*AP*A)-3'), DNA (5'-D(*GP*TP*TP*TP*GP*GP*AP*TP*TP*AP*AP*GP*TP*GP*TP*T)-3'), LMX1A factor 著者 Lv, M.Q, Lin, L.Q. 登録日 2023-03-04 公開日 2024-03-06 実験手法 X-RAY DIFFRACTION (2.712 Å) 主引用文献 Structural insights into the recognition of the A/T-rich motif in target gene promoters by the LMX1a homeobox domain Febs J., 2024
5ULO	Crystal Structure of 14-3-3 zeta in Complex with a Serine 124-phosphorylated TBC1D7 peptide 分子名称: 1,2-ETHANEDIOL, 14-3-3 protein zeta/delta, L-PROLINAMIDE, ... 著者 DONG, A, HU, J, MADIGAN, J, WALKER, J.R, Bountra, C, Arrowsmith, C.H, Edwards, A.M, TONG, Y, Structural Genomics Consortium (SGC) 登録日 2017-01-25 公開日 2018-01-31 最終更新日 2023-10-04 実験手法 X-RAY DIFFRACTION (2.14 Å) 主引用文献 Crystal Structure of 14-3-3 zeta in Complex with a Serine 124-phosphorylated TBC1D7 peptide to be published
6T80	Human 14-3-3 sigma fused to the AANAT peptide including phosphoserine-205 分子名称: 14-3-3 protein sigma, AANAT peptide 著者 Sluchanko, N.N, Tugaeva, K.V, Titterington, J, Antson, A.A. 登録日 2019-10-23 公開日 2020-11-18 最終更新日 2024-01-24 実験手法 X-RAY DIFFRACTION (2.99 Å) 主引用文献 Human 14-3-3 sigma fused to the AANAT peptide including phosphoserine-205 To Be Published
6T78	Structure of human Sox11 transcription factor in complex with a short DNA fragment 分子名称: DNA (5'-D(*AP*AP*CP*AP*AP*AP*AP*TP*AP*AP*AP*CP*AP*AP*TP*A)-3'), DNA (5'-D(*TP*AP*TP*TP*GP*TP*TP*TP*AP*TP*TP*TP*TP*GP*TP*T)-3'), Transcription factor SOX-11 著者 Dodonova, S.O, Zhu, F, Dienemann, C, Taipale, J, Cramer, P. 登録日 2019-10-21 公開日 2020-04-29 最終更新日 2024-01-24 実験手法 X-RAY DIFFRACTION (2.504 Å) 主引用文献 Nucleosome-bound SOX2 and SOX11 structures elucidate pioneer factor function. Nature, 580, 2020
6T7F	RCR E3 ligase E2-Ubiquitin transthiolation intermediate 分子名称: 3,3-bis(sulfanyl)-~{N}-(1~{H}-1,2,3-triazol-4-ylmethyl)propanamide, E3 ubiquitin-protein ligase MYCBP2, Polyubiquitin-C, ... 著者 Mabbitt, P.D, Virdee, S. 登録日 2019-10-21 公開日 2020-08-05 最終更新日 2024-01-24 実験手法 X-RAY DIFFRACTION (2.58 Å) 主引用文献 Structural basis for RING-Cys-Relay E3 ligase activity and its role in axon integrity. Nat.Chem.Biol., 16, 2020
6T5H	Human 14-3-3 sigma fused to the StARD1 peptide including phosphoserine-57 分子名称: 14-3-3 protein sigma,Steroidogenic acute regulatory protein, mitochondrial, IMIDAZOLE, ... 著者 Sluchanko, N.N, Tugaeva, K.V, Titterington, J, Antson, A.A. 登録日 2019-10-16 公開日 2020-11-18 最終更新日 2024-01-24 実験手法 X-RAY DIFFRACTION (2.04 Å) 主引用文献 Molecular basis for the recognition of steroidogenic acute regulatory protein by the 14-3-3 protein family. Febs J., 287, 2020
6TLD	Crystal structure of Schistosoma mansoni HDAC8 complexed with a triazole hydroxamate inhibitor 2 分子名称: DIMETHYLFORMAMIDE, GLYCEROL, Histone deacetylase, ... 著者 Shaik, T.B, Romier, C. 登録日 2019-12-02 公開日 2019-12-18 最終更新日 2024-01-24 実験手法 X-RAY DIFFRACTION (1.61 Å) 主引用文献 Structure-Based Design, Synthesis, and Biological Evaluation of Triazole-Based smHDAC8 Inhibitors. Chemmedchem, 15, 2020
8J1N	Structure of human UCP1 in the DNP-bound state 分子名称: 1,2-DIACYL-SN-GLYCERO-3-PHOSPHOCHOLINE, 2,4-DINITROPHENOL, CARDIOLIPIN, ... 著者 Chen, L, Kang, Y. 登録日 2023-04-13 公開日 2023-06-21 最終更新日 2023-08-30 実験手法 ELECTRON MICROSCOPY (2.51 Å) 主引用文献 Structural basis for the binding of DNP and purine nucleotides onto UCP1. Nature, 620, 2023
6TM7	Human 14-3-3 sigma isoform in complex with PLP 分子名称: 14-3-3 protein sigma, PYRIDOXAL-5'-PHOSPHATE, SULFATE ION 著者 Tassone, G, Pozzi, C, Mangani, S. 登録日 2019-12-03 公開日 2020-03-18 最終更新日 2024-01-24 実験手法 X-RAY DIFFRACTION (3 Å) 主引用文献 Identification of Phosphate-Containing Compounds as New Inhibitors of 14-3-3/c-Abl Protein-Protein Interaction. Acs Chem.Biol., 15, 2020
6K0C	Crystal structure of ceNAP1-H2A.Z-H2B complex 分子名称: Histone H2B 2,Histone H2A.V, Nucleosome Assembly Protein 著者 Liu, Y.R. 登録日 2019-05-05 公開日 2019-10-09 最終更新日 2024-03-27 実験手法 X-RAY DIFFRACTION (2.281 Å) 主引用文献 Crystal structure of xlH2A-H2B Structure, 2019
7CTE	Human Origin Recognition Complex, ORC2-5 分子名称: ADENOSINE-5'-TRIPHOSPHATE, Origin recognition complex subunit 2, Origin recognition complex subunit 3, ... 著者 Cheng, J, Li, N, Wang, X, Hu, J, Zhai, Y, Gao, N. 登録日 2020-08-18 公開日 2021-01-06 最終更新日 2024-03-27 実験手法 ELECTRON MICROSCOPY (3.8 Å) 主引用文献 Structural insight into the assembly and conformational activation of human origin recognition complex. Cell Discov, 6, 2020
6K00	Crystal structure A of ceNAP1-H2A-H2B complex 分子名称: Histone H2B 1,Histone H2A, Nucleosome Assembly Protein 著者 Liu, Y.R. 登録日 2019-05-05 公開日 2019-10-09 最終更新日 2024-03-27 実験手法 X-RAY DIFFRACTION (2.198 Å) 主引用文献 Crystal structure of xlH2A-H2B Structure, 2019
8IY6	ETB-Gi complex bound to Endotheline-1, focused on receptor 分子名称: Endothelin type B receptor, Endothelin-1 著者 Sano, F.K, Akasaka, H, Shihoya, W, Nureki, O. 登録日 2023-04-04 公開日 2023-08-16 最終更新日 2023-12-06 実験手法 ELECTRON MICROSCOPY (3.13 Å) 主引用文献 Cryo-EM structure of the endothelin-1-ET B -G i complex. Elife, 12, 2023
8IY5	ETB-Gi complex bound to endothelin-1 分子名称: Endothelin type B receptor, Endothelin-1, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, ... 著者 Sano, F.K, Akasaka, H, Shihoya, W, Nureki, O. 登録日 2023-04-04 公開日 2023-08-16 最終更新日 2023-12-06 実験手法 ELECTRON MICROSCOPY (2.8 Å) 主引用文献 Cryo-EM structure of the endothelin-1-ET B -G i complex. Elife, 12, 2023
6TWZ	14-3-3 sigma complexed with a phosphorylated 16E6 peptide 分子名称: 14-3-3 protein sigma, 2-[3-(2-HYDROXY-1,1-DIHYDROXYMETHYL-ETHYLAMINO)-PROPYLAMINO]-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, D(-)-TARTARIC ACID, ... 著者 Gogl, G, Cousido-Siah, A, Sluchanko, N.N, Trave, G. 登録日 2020-01-13 公開日 2020-05-06 最終更新日 2024-01-24 実験手法 X-RAY DIFFRACTION (2.8 Å) 主引用文献 Dual Specificity PDZ- and 14-3-3-Binding Motifs: A Structural and Interactomics Study. Structure, 28, 2020

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