8J1N

Structure of human UCP1 in the DNP-bound state

Summary for 8J1N

• Entry DOI: 10.2210/pdb8j1n/pdb
• EMDB information: 35928
• Descriptor: Mitochondrial brown fat uncoupling protein 1, Sybody 12F2, 2,4-DINITROPHENOL, ... (5 entities in total)
• Functional Keywords: ucp1, slc25a7, thermogenin, slc25, membrane protein
• Biological source: Homo sapiens (human); More
• Total number of polymer chains: 2
• Total formula weight: 57701.47

Authors

Chen, L.,Kang, Y. (deposition date: 2023-04-13, release date: 2023-06-21, Last modification date: 2023-08-30)

• Primary citation: Kang, Y.,Chen, L.; Structural basis for the binding of DNP and purine nucleotides onto UCP1.; Nature, 620:226-231, 2023; PubMed: 37336486; DOI: 10.1038/s41586-023-06332-w

Experimental method

ELECTRON MICROSCOPY (2.51 Å)