8J1N
Structure of human UCP1 in the DNP-bound state
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Mitochondrial brown fat uncoupling protein 1 | polymer | 363 | 39468.4 | 1 | UniProt (P25874) Pfam (PF00153) | Homo sapiens (human) | UCP 1,Solute carrier family 25 member 7,Thermogenin |
| 2 | B (B) | Sybody 12F2 | polymer | 131 | 15004.7 | 1 | synthetic construct | ||
| 3 | C (A) | 2,4-DINITROPHENOL | non-polymer | 184.1 | 1 | Chemie (DNF) | |||
| 4 | D (A) | CARDIOLIPIN | non-polymer | 1464.0 | 1 | Chemie (CDL) | |||
| 5 | E, F (A) | 1,2-DIACYL-SN-GLYCERO-3-PHOSPHOCHOLINE | non-polymer | 790.1 | 2 | Chemie (PC1) |
Sequence modifications
A: 0 - 306 (UniProt: P25874)
| PDB | External Database | Details |
|---|---|---|
| Met -56 | - | initiating methionine |
| Ser -55 | - | expression tag |
| Arg -54 | - | expression tag |
| Leu -53 | - | expression tag |
| Glu -52 | - | expression tag |
| Glu -51 | - | expression tag |
| Glu -50 | - | expression tag |
| Leu -49 | - | expression tag |
| Arg -48 | - | expression tag |
| Arg -47 | - | expression tag |
| Arg -46 | - | expression tag |
| Leu -45 | - | expression tag |
| Thr -44 | - | expression tag |
| Glu -43 | - | expression tag |
| Gly -42 | - | expression tag |
| Ser -41 | - | expression tag |
| Gly -40 | - | expression tag |
| Gly -39 | - | expression tag |
| Trp -38 | - | expression tag |
| Ser -37 | - | expression tag |
| His -36 | - | expression tag |
| Pro -35 | - | expression tag |
| Gln -34 | - | expression tag |
| Phe -33 | - | expression tag |
| Glu -32 | - | expression tag |
| Lys -31 | - | expression tag |
| Gly -30 | - | expression tag |
| Ser -29 | - | expression tag |
| Gly -28 | - | expression tag |
| Asp -27 | - | expression tag |
| Tyr -26 | - | expression tag |
| Lys -25 | - | expression tag |
| Asp -24 | - | expression tag |
| Asp -23 | - | expression tag |
| Asp -22 | - | expression tag |
| Asp -21 | - | expression tag |
| Lys -20 | - | expression tag |
| Gly -19 | - | expression tag |
| Ser -18 | - | expression tag |
| Gly -17 | - | expression tag |
| Trp -16 | - | expression tag |
| Ser -15 | - | expression tag |
| His -14 | - | expression tag |
| Pro -13 | - | expression tag |
| Gln -12 | - | expression tag |
| Phe -11 | - | expression tag |
| Glu -10 | - | expression tag |
| Lys -9 | - | expression tag |
| Leu -8 | - | expression tag |
| Glu -7 | - | expression tag |
| Val -6 | - | expression tag |
| Leu -5 | - | expression tag |
| Phe -4 | - | expression tag |
| Gln -3 | - | expression tag |
| Gly -2 | - | expression tag |
| Pro -1 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 54473.0 | |
| Non-Polymers* | Number of molecules | 4 |
| Total formula weight | 3228.4 | |
| All* | Total formula weight | 57701.5 |
