6TA2

Human NAMPT in complex with nicotinic acid mononucleotide and phosphate

Summary for 6TA2

• Entry DOI: 10.2210/pdb6ta2/pdb
• Related: 6TA0
• Descriptor: Nicotinamide phosphoribosyltransferase, GLYCEROL, NICOTINATE MONONUCLEOTIDE, ... (6 entities in total)
• Functional Keywords: nad biosynthesis, substrate complex, transferase
• Biological source: Homo sapiens (Human)
• Total number of polymer chains: 2
• Total formula weight: 115024.30

Authors

Houry, D.,Raasakka, A.,Kursula, P.,Ziegler, M. (deposition date: 2019-10-29, release date: 2020-11-18, Last modification date: 2024-01-24)

• Primary citation: Houry, D.,Raasakka, A.,Kursula, P.,Ziegler, M.; Identification of structural determinants of NAMPT activity and substrate selectivity; To Be Published,

Experimental method

X-RAY DIFFRACTION (1.68 Å)