6TA0

Human NAMPT in complex with nicotinic acid and phosphoribosyl pyrophosphate

Summary for 6TA0

• Entry DOI: 10.2210/pdb6ta0/pdb
• Descriptor: Nicotinamide phosphoribosyltransferase, 1-O-pyrophosphono-5-O-phosphono-alpha-D-ribofuranose, GLYCEROL, ... (5 entities in total)
• Functional Keywords: nad biosynthesis, substrate complex, transferase
• Biological source: Homo sapiens (Human)
• Total number of polymer chains: 2
• Total formula weight: 115211.49

Authors

Houry, D.,Raasakka, A.,Kursula, P.,Ziegler, M. (deposition date: 2019-10-29, release date: 2020-11-18, Last modification date: 2024-01-24)

• Primary citation: Houry, D.,Raasakka, A.,Kursula, P.,Ziegler, M.; Identification of structural determinants of NAMPT activity and substrate selectivity; To Be Published,

Experimental method

X-RAY DIFFRACTION (1.58 Å)