6TA0
Human NAMPT in complex with nicotinic acid and phosphoribosyl pyrophosphate
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A, B | Nicotinamide phosphoribosyltransferase | polymer | 503 | 57000.5 | 2 | UniProt (P43490) Pfam (PF18127) Pfam (PF04095) In PDB | Homo sapiens (Human) | Nampt,Pre-B-cell colony-enhancing factor 1,Pre-B cell-enhancing factor,Visfatin |
2 | A | 1-O-pyrophosphono-5-O-phosphono-alpha-D-ribofuranose | non-polymer | 390.1 | 2 | Chemie (PRP) | |||
3 | A, B | GLYCEROL | non-polymer | 92.1 | 2 | Chemie (GOL) | |||
4 | A, B | NICOTINIC ACID | non-polymer | 123.1 | 2 | Chemie (NIO) | |||
5 | water | water | 18.0 | 840 | Chemie (HOH) |
Sequence modifications
A, B: 1 - 491 (UniProt: P43490)
PDB | External Database | Details |
---|---|---|
Met -11 | - | initiating methionine |
Arg -10 | - | expression tag |
Gly -9 | - | expression tag |
Ser -8 | - | expression tag |
His -7 | - | expression tag |
His -6 | - | expression tag |
His -5 | - | expression tag |
His -4 | - | expression tag |
His -3 | - | expression tag |
His -2 | - | expression tag |
Gly -1 | - | expression tag |
Ser 0 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 2 |
Total formula weight | 114000.9 | |
Non-Polymers* | Number of molecules | 6 |
Total formula weight | 1210.5 | |
All* | Total formula weight | 115211.5 |