6TM7

Human 14-3-3 sigma isoform in complex with PLP

Summary for 6TM7

Entry DOI	10.2210/pdb6tm7/pdb
Related	6TLF 6TLG
Descriptor	14-3-3 protein sigma, SULFATE ION, PYRIDOXAL-5'-PHOSPHATE, ... (4 entities in total)
Functional Keywords	human protein, h14-3-3sigma, signaling protein, complex, pyridoxal phosphate, plp
Biological source	Homo sapiens (Human)
Total number of polymer chains	2
Total formula weight	62808.66
Authors	Tassone, G.,Pozzi, C.,Mangani, S. (deposition date: 2019-12-03, release date: 2020-03-18, Last modification date: 2024-01-24)
Primary citation	Iralde-Lorente, L.,Tassone, G.,Clementi, L.,Franci, L.,Munier, C.C.,Cau, Y.,Mori, M.,Chiariello, M.,Angelucci, A.,Perry, M.W.D.,Pozzi, C.,Mangani, S.,Botta, M. Identification of Phosphate-Containing Compounds as New Inhibitors of 14-3-3/c-Abl Protein-Protein Interaction. Acs Chem.Biol., 15:1026-1035, 2020 Cited by PubMed: 32142251 DOI: 10.1021/acschembio.0c00039 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (3 Å)

Structure validation