6T78

Structure of human Sox11 transcription factor in complex with a short DNA fragment

Summary for 6T78

• Entry DOI: 10.2210/pdb6t78/pdb
• Descriptor: Transcription factor SOX-11, DNA (5'-D(*TP*AP*TP*TP*GP*TP*TP*TP*AP*TP*TP*TP*TP*GP*TP*T)-3'), DNA (5'-D(*AP*AP*CP*AP*AP*AP*AP*TP*AP*AP*AP*CP*AP*AP*TP*A)-3'), ... (4 entities in total)
• Functional Keywords: sox11, transcription factor, pioneer factor, dna, nuclear protein
• Biological source: Homo sapiens (Human); More
• Total number of polymer chains: 6
• Total formula weight: 45294.79

Authors

Dodonova, S.O.,Zhu, F.,Dienemann, C.,Taipale, J.,Cramer, P. (deposition date: 2019-10-21, release date: 2020-04-29, Last modification date: 2024-01-24)

• Primary citation: Dodonova, S.O.,Zhu, F.,Dienemann, C.,Taipale, J.,Cramer, P.; Nucleosome-bound SOX2 and SOX11 structures elucidate pioneer factor function.; Nature, 580:669-672, 2020; PubMed: 32350470; DOI: 10.1038/s41586-020-2195-y

Experimental method

X-RAY DIFFRACTION (2.504 Å)