5U5S

Solution structures of Brd2 second bromodomain in complex with stat3 peptide

Summary for 5U5S

• Entry DOI: 10.2210/pdb5u5s/pdb
• NMR Information: BMRB: 30206
• Descriptor: Bromodomain-containing protein 2, Stat3 peptide (2 entities in total)
• Functional Keywords: brd2, brd4, bromodomain, stat3, th17, p300, transcription
• Biological source: Homo sapiens (Human); More
• Total number of polymer chains: 2
• Total formula weight: 14697.94

Authors

Zeng, L.,Zhou, M.-M. (deposition date: 2016-12-07, release date: 2017-03-22, Last modification date: 2023-11-15)

• Primary citation: Cheung, K.L.,Zhang, F.,Jaganathan, A.,Sharma, R.,Zhang, Q.,Konuma, T.,Shen, T.,Lee, J.Y.,Ren, C.,Chen, C.H.,Lu, G.,Olson, M.R.,Zhang, W.,Kaplan, M.H.,Littman, D.R.,Walsh, M.J.,Xiong, H.,Zeng, L.,Zhou, M.M.; Distinct Roles of Brd2 and Brd4 in Potentiating the Transcriptional Program for Th17 Cell Differentiation.; Mol. Cell, 65:1068-1080.e5, 2017; PubMed: 28262505; DOI: 10.1016/j.molcel.2016.12.022

Experimental method

SOLUTION NMR