7BM9
Crystal structure of 14-3-3 sigma in complex with CIP2ApS904 peptide
Summary for 7BM9
Entry DOI | 10.2210/pdb7bm9/pdb |
Descriptor | 14-3-3 protein sigma, VAL-ASN-LEU-SEP-ILE, CHLORIDE ION, ... (5 entities in total) |
Functional Keywords | protein-peptide complex, signaling protein |
Biological source | Homo sapiens (Human) More |
Total number of polymer chains | 2 |
Total formula weight | 28935.20 |
Authors | Centorrino, F.,Andlovic, B.,Ottmann, C. (deposition date: 2021-01-19, release date: 2022-03-02, Last modification date: 2024-01-31) |
Primary citation | Brink, H.J.,van Senten, J.R.,De Vries-van Leeuwen, I.J.,da Costa Pereira, D.,Piersma, S.R.,Jimenez, C.R.,Centorrino, F.,Ottmann, C.,Siderius, M.,Smit, M.J.,de Boer, A.H. Fusicoccin-A Targets Cancerous Inhibitor of Protein Phosphatase 2A by Stabilizing a C-Terminal Interaction with 14-3-3. Acs Chem.Biol., 17:2972-2978, 2022 Cited by PubMed: 36255265DOI: 10.1021/acschembio.2c00299 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.8 Å) |
Structure validation
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