PDB: 46984 件ウェブページステータス検索Chemie searchBIRD

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1BAL	THREE-DIMENSIONAL SOLUTION STRUCTURE OF THE E3-BINDING DOMAIN OF THE DIHYDROLIPOAMIDE SUCCINYLTRANSFERASE CORE FROM THE 2-OXOGLUTARATE DEHYDROGENASE MULTIENZYME COMPLEX OF (ESCHERICHIA COLI) 分子名称: DIHYDROLIPOAMIDE SUCCINYLTRANSFERASE 著者 Clore, G.M, Robien, M.A, Gronenborn, A.M. 登録日 1992-02-20 公開日 1994-01-31 最終更新日 2024-05-22 実験手法 SOLUTION NMR 主引用文献 Three-dimensional solution structure of the E3-binding domain of the dihydrolipoamide succinyltransferase core from the 2-oxoglutarate dehydrogenase multienzyme complex of Escherichia coli. Biochemistry, 31, 1992
4AA5	P38ALPHA MAP KINASE BOUND TO CMPD 33 分子名称: MITOGEN-ACTIVATED PROTEIN KINASE 14, N-CYCLOPROPYL-4-METHYL-3-[6-(4-METHYLPIPERAZIN-1-YL)-4-OXIDANYLIDENE-QUINAZOLIN-3-YL]BENZAMIDE 著者 Gerhardt, S, Hargreaves, D. 登録日 2011-11-30 公開日 2012-05-16 最終更新日 2019-02-06 実験手法 X-RAY DIFFRACTION (2.38 Å) 主引用文献 The Discovery of N-Cyclopropyl-4-Methyl-3-[6--(4-Methylpiperazin-1-Yl-4-Oxoquinazolin-3(4H)-Yl]Benzamide (Azd6703), a Clinical P38Alpha Map Kinase Inhibitor for the Treatment of Inflammatory Diseases Bioorg.Med.Chem.Lett., 22, 2012
1BF3	P-HYDROXYBENZOATE HYDROXYLASE (PHBH) MUTANT WITH CYS 116 REPLACED BY SER (C116S) AND ARG 42 REPLACED BY LYS (R42K), IN COMPLEX WITH FAD AND 4-HYDROXYBENZOIC ACID 分子名称: FLAVIN-ADENINE DINUCLEOTIDE, P-HYDROXYBENZOATE HYDROXYLASE, P-HYDROXYBENZOIC ACID 著者 Eppink, M.H.M, Schreuder, H.A, Van Berkel, W.J.H. 登録日 1998-05-26 公開日 1998-08-12 最終更新日 2024-05-22 実験手法 X-RAY DIFFRACTION (2.2 Å) 主引用文献 Lys42 and Ser42 variants of p-hydroxybenzoate hydroxylase from Pseudomonas fluorescens reveal that Arg42 is essential for NADPH binding. Eur.J.Biochem., 253, 1998
8K5O	Cryo-EM structure of the RC-LH core comples from Halorhodospira halochloris 分子名称: (1R)-2-{[{[(2S)-2,3-DIHYDROXYPROPYL]OXY}(HYDROXY)PHOSPHORYL]OXY}-1-[(PALMITOYLOXY)METHYL]ETHYL (11E)-OCTADEC-11-ENOATE, 1,2-DIPALMITOYL-PHOSPHATIDYL-GLYCEROLE, 2-O-octyl-beta-D-glucopyranose, ... 著者 Wang, G.-L, Qi, C.-H, Yu, L.-J. 登録日 2023-07-22 公開日 2024-05-22 実験手法 ELECTRON MICROSCOPY (2.42 Å) 主引用文献 Structural insights into the unusual core photocomplex from a triply extremophilic purple bacterium, Halorhodospira halochloris. J Integr Plant Biol, 2024
1AZH	THREE-DIMENSIONAL STRUCTURES OF THREE ENGINEERED CELLULOSE-BINDING DOMAINS OF CELLOBIOHYDROLASE I FROM TRICHODERMA REESEI, NMR, 14 STRUCTURES 分子名称: CELLOBIOHYDROLASE I 著者 Mattinen, M.-L. 登録日 1997-11-18 公開日 1998-04-08 最終更新日 2021-11-03 実験手法 SOLUTION NMR 主引用文献 Three-dimensional structures of three engineered cellulose-binding domains of cellobiohydrolase I from Trichoderma reesei. Protein Sci., 6, 1997
1BBL	THREE-DIMENSIONAL SOLUTION STRUCTURE OF THE E3-BINDING DOMAIN OF THE DIHYDROLIPOAMIDE SUCCINYLTRANSFERASE CORE FROM THE 2-OXOGLUTARATE DEHYDROGENASE MULTIENZYME COMPLEX OF ESCHERICHIA COLI 分子名称: DIHYDROLIPOAMIDE SUCCINYLTRANSFERASE 著者 Clore, G.M, Robien, M.A, Gronenborn, A.M. 登録日 1992-02-20 公開日 1994-01-31 最終更新日 2024-05-22 実験手法 SOLUTION NMR 主引用文献 Three-dimensional solution structure of the E3-binding domain of the dihydrolipoamide succinyltransferase core from the 2-oxoglutarate dehydrogenase multienzyme complex of Escherichia coli. Biochemistry, 31, 1992
6R6G	Structure of XBP1u-paused ribosome nascent chain complex with SRP. 分子名称: 18S ribosomal RNA, 28S ribosomal RNA, 40S ribosomal protein S12, ... 著者 Shanmuganathan, V, Cheng, J, Braunger, K, Berninghausen, O, Beatrix, B, Beckmann, R. 登録日 2019-03-27 公開日 2019-07-10 最終更新日 2019-10-30 実験手法 ELECTRON MICROSCOPY (3.7 Å) 主引用文献 Structural and mutational analysis of the ribosome-arresting human XBP1u. Elife, 8, 2019
1BKW	p-Hydroxybenzoate hydroxylase (phbh) mutant with cys116 replaced by ser (c116s) and arg44 replaced by lys (r44k), in complex with fad and 4-hydroxybenzoic acid 分子名称: FLAVIN-ADENINE DINUCLEOTIDE, P-HYDROXYBENZOIC ACID, PROTEIN (P-HYDROXYBENZOATE HYDROXYLASE) 著者 Eppink, M.H, Schreuder, H.A, Van Berkel, W.J. 登録日 1998-07-13 公開日 1998-07-22 最終更新日 2023-08-09 実験手法 X-RAY DIFFRACTION (2.2 Å) 主引用文献 Structure and function of mutant Arg44Lys of 4-hydroxybenzoate hydroxylase implications for NADPH binding. Eur.J.Biochem., 231, 1995
8EFJ	A structural study of selectivity mechanisms for JNK3 and p38 alpha with indazole scaffold probing compounds 分子名称: (4P)-4-[5-(2-chloro-6-fluoroanilino)-6-(methoxymethyl)-1H-indazol-1-yl]-N-methylthiophene-2-carboxamide, Mitogen-activated protein kinase 14, octyl beta-D-glucopyranoside 著者 Park, H, Feng, Y. 登録日 2022-09-08 公開日 2023-09-20 実験手法 X-RAY DIFFRACTION (2.31 Å) 主引用文献 A structural study of selectivity mechanisms for JNK3 and p38 alpha with indazole scaffold probing compounds To Be Published
1BZG	THE SOLUTION STRUCTURE OF HUMAN PARATHYROID HORMONE-RELATED PROTEIN (1-34) IN NEAR-PHYSIOLOGICAL SOLUTION, NMR, 30 STRUCTURES 分子名称: PARATHYROID HORMONE-RELATED PROTEIN 著者 Weidler, M, Marx, U.C, Seidel, G, Roesch, P. 登録日 1998-10-28 公開日 1999-05-18 最終更新日 2024-05-22 実験手法 SOLUTION NMR 主引用文献 The structure of human parathyroid hormone-related protein(1-34) in near-physiological solution. FEBS Lett., 444, 1999
6QYX	p38(alpha) MAP kinase with the activation loop of ERK2 分子名称: 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, Mitogen-activated protein kinase 14,Mitogen-activated protein kinase 1,Mitogen-activated protein kinase 14, octyl beta-D-glucopyranoside 著者 Livnah, O, Eitan-Wexler, M, Vinograd, N. 登録日 2019-03-10 公開日 2020-04-01 最終更新日 2024-05-01 実験手法 X-RAY DIFFRACTION (1.66 Å) 主引用文献 The bacterial metalloprotease NleD selectively cleaves mitogen-activated protein kinases that have high flexibility in their activation loop. J.Biol.Chem., 295, 2020
2GV7	Structure of Matriptase in Complex with Inhibitor CJ-672 分子名称: (S)-4-(4-(3-(3-CARBAMIMIDOYLPHENYL)-2-(2,4,6-TRIISOPROPYLPHENYLSULFONAMIDO)PROPANOYL)PIPERAZINE-1-CARBONYL)PIPERIDINE-1-CARBOXIMIDAMIDE, Suppressor of tumorigenicity 14 著者 Bode, W. 登録日 2006-05-02 公開日 2006-06-06 最終更新日 2011-07-13 実験手法 X-RAY DIFFRACTION (2.2 Å) 主引用文献 Secondary Amides of Sulfonylated 3-Amidinophenylalanine. New Potent and Selective Inhibitors of Matriptase. J.Med.Chem., 49, 2006
3H1H	Cytochrome bc1 complex from chicken 分子名称: 1,2-Dioleoyl-sn-glycero-3-phosphoethanolamine, CARDIOLIPIN, CYTOCHROME C1, ... 著者 Zhang, Z, Huang, L, Shulmeister, V.M, Chi, Y.I, Kim, K.K, Hung, L.W, Crofts, A.R, Berry, E.A, Kim, S.H. 登録日 2009-04-12 公開日 2009-04-28 最終更新日 2020-07-29 実験手法 X-RAY DIFFRACTION (3.16 Å) 主引用文献 Electron Transfer by Domain Movement in Cytochrome Bc1 Nature, 392, 1998
5T7V	Methicillin Resistant, Linezolid resistant Staphylococcus aureus 70S ribosome (delta S145 uL3) 分子名称: 16S ribosomal RNA, 23S ribosomal RNA, 30S ribosomal protein S10, ... 著者 Belousoff, M.J, Lithgow, T, Eyal, Z, Yonath, A, Radjainia, M. 登録日 2016-09-06 公開日 2017-05-31 最終更新日 2019-12-11 実験手法 ELECTRON MICROSCOPY (3.6 Å) 主引用文献 Structural Basis for Linezolid Binding Site Rearrangement in theStaphylococcus aureusRibosome. MBio, 8, 2017
4D6Z	Cytochrome P450 3A4 bound to imidazole and an inhibitor 分子名称: CYTOCHROME P450 3A4, GLYCEROL, IMIDAZOLE, ... 著者 Sevrioukova, I, Poulos, T. 登録日 2014-11-19 公開日 2015-09-23 最終更新日 2023-12-20 実験手法 X-RAY DIFFRACTION (1.93 Å) 主引用文献 Structure-Based Inhibitor Design for Evaluation of a Cyp3A4 Pharmacophore Model. J.Med.Chem., 59, 2016
4D7D	Cytochrome P450 3A4 bound to an inhibitor 分子名称: CYTOCHROME P450 3A4, PROTOPORPHYRIN IX CONTAINING FE, tert-butyl [(2S)-1-(1H-indol-3-yl)-3-({3-oxo-3-[(pyridin-3-ylmethyl)amino]propyl}sulfanyl)propan-2-yl]carbamate 著者 Sevrioukova, I, Poulos, T. 登録日 2014-11-22 公開日 2015-09-23 最終更新日 2023-12-20 実験手法 X-RAY DIFFRACTION (2.76 Å) 主引用文献 Structure-Based Inhibitor Design for Evaluation of a Cyp3A4 Pharmacophore Model. J.Med.Chem., 59, 2016
4D75	Cytochrome P450 3A4 bound to an inhibitor 分子名称: CYTOCHROME P450 3A4, PROTOPORPHYRIN IX CONTAINING FE, tert-butyl {6-oxo-6-[(pyridin-3-ylmethyl)amino]hexyl}carbamate 著者 Sevrioukova, I, Poulos, T. 登録日 2014-11-19 公開日 2015-09-23 最終更新日 2023-12-20 実験手法 X-RAY DIFFRACTION (2.25 Å) 主引用文献 Structure-Based Inhibitor Design for Evaluation of a Cyp3A4 Pharmacophore Model. J.Med.Chem., 59, 2016
4D78	Cytochrome P450 3A4 bound to an inhibitor 分子名称: CYTOCHROME P450 3A4, GLYCEROL, PROTOPORPHYRIN IX CONTAINING FE, ... 著者 Sevrioukova, I, Poulos, T. 登録日 2014-11-21 公開日 2015-09-23 最終更新日 2023-12-20 実験手法 X-RAY DIFFRACTION (2.8 Å) 主引用文献 Structure-Based Inhibitor Design for Evaluation of a Cyp3A4 Pharmacophore Model. J.Med.Chem., 59, 2016
2GV6	Crystal Structure of Matriptase with Inhibitor CJ-730 分子名称: (S)-3-(3-(4-(2-GUANIDINOETHYL)PIPERIDIN-1-YL)-2-(NAPHTHALENE-2-SULFONAMIDO)-3-OXOPROPYL)BENZIMIDAMIDE, Suppressor of tumorigenicity 14 著者 Bode, W. 登録日 2006-05-02 公開日 2006-06-06 最終更新日 2021-06-23 実験手法 X-RAY DIFFRACTION (2.1 Å) 主引用文献 Secondary Amides of Sulfonylated 3-Amidinophenylalanine. New Potent and Selective Inhibitors of Matriptase. J.Med.Chem., 49, 2006
3J9T	Yeast V-ATPase state 1 分子名称: V-type proton ATPase catalytic subunit A, V-type proton ATPase subunit B, V-type proton ATPase subunit C, ... 著者 Zhao, J, Benlekbir, S, Rubinstein, J.L. 登録日 2015-02-23 公開日 2015-05-13 最終更新日 2024-02-21 実験手法 ELECTRON MICROSCOPY (6.9 Å) 主引用文献 Electron cryomicroscopy observation of rotational states in a eukaryotic V-ATPase. Nature, 521, 2015
2GOF	Three-dimensional structure of the trans-membrane domain of Vpu from HIV-1 in aligned phospholipid bicelles 分子名称: VPU protein 著者 Park, S.H, De Angelis, A.A, Nevzorov, A.A, Wu, C.H, Opella, S.J. 登録日 2006-04-12 公開日 2006-08-08 最終更新日 2024-05-29 実験手法 SOLUTION NMR 主引用文献 Three-Dimensional Structure of the Transmembrane Domain of Vpu from HIV-1 in Aligned Phospholipid Bicelles. Biophys.J., 91, 2006
2K3U	Structure of the tyrosine-sulfated C5a receptor N-terminus in complex with the immune evasion protein CHIPS. 分子名称: C5a anaphylatoxin chemotactic receptor 1, Chemotaxis inhibitory protein 著者 Ippel, J.H, Bunschoten, A, Kemmink, J, Liskamp, R. 登録日 2008-05-16 公開日 2009-03-10 最終更新日 2023-11-15 実験手法 SOLUTION NMR 主引用文献 Structure of the Tyrosine-sulfated C5a Receptor N Terminus in Complex with Chemotaxis Inhibitory Protein of Staphylococcus aureus. J.Biol.Chem., 284, 2009
2YIW	triazolopyridine inhibitors of p38 kinase 分子名称: 1-(3-tert-butyl-1-phenyl-1H-pyrazol-5-yl)-3-(2-{[3-(1-methylethyl)[1,2,4]triazolo[4,3-a]pyridin-6-yl]sulfanyl}benzyl)urea, 2-fluoro-4-[4-(4-fluorophenyl)-1H-pyrazol-3-yl]pyridine, MITOGEN-ACTIVATED PROTEIN KINASE 14 著者 Millan, D.S, Anderson, M, Bunnage, M.E, Burrows, J.L, Butcher, K.J, Dodd, P.G, Evans, T.J, Fairman, D.A, Hughes, S.J, Irving, S.L, Kilty, I.C, Lemaitre, A, Lewthwaite, R.A, Mahnke, A, Mathais, J.P, Philip, J, Phillips, C, Smith, R.T, Stefamiak, M.H, Yeadon, M. 登録日 2011-05-17 公開日 2011-11-30 最終更新日 2024-05-08 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 Design and Synthesis of Inhaled P38 Inhibitors for the Treatment of Chronic Obstructive Pulmonary Disease. J.Med.Chem., 54, 2011
4R4N	Crystal structure of the anti-hiv-1 antibody 2.2c in complex with hiv-1 93ug037 gp120 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, Antibody 2.2c LIGHT CHAIN, Antibody 2.2c heavy CHAIN, ... 著者 Acharya, P, Louder, R, Kwong, P.D. 登録日 2014-08-19 公開日 2014-11-05 最終更新日 2024-01-10 実験手法 X-RAY DIFFRACTION (3.56 Å) 主引用文献 Structural Definition of an Antibody-Dependent Cellular Cytotoxicity Response Implicated in Reduced Risk for HIV-1 Infection. J.Virol., 88, 2014
4QYK	Crystal structure of a canine parvovirus variant 分子名称: Capsid protein VP1, MAGNESIUM ION 著者 Lukk, T, Organtini, L.J, Hafenstein, S.U. 登録日 2014-07-24 公開日 2014-12-10 最終更新日 2015-01-28 実験手法 X-RAY DIFFRACTION (3.5 Å) 主引用文献 Global Displacement of Canine Parvovirus by a Host-Adapted Variant: Structural Comparison between Pandemic Viruses with Distinct Host Ranges. J.Virol., 89, 2015

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