6QYX

p38(alpha) MAP kinase with the activation loop of ERK2

Summary for 6QYX

• Entry DOI: 10.2210/pdb6qyx/pdb
• Related: 2NPQ
• Descriptor: Mitogen-activated protein kinase 14,Mitogen-activated protein kinase 1,Mitogen-activated protein kinase 14, octyl beta-D-glucopyranoside, 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, ... (4 entities in total)
• Functional Keywords: nled, effector, t3ss, map kinase, phosphorylation, transferase
• Biological source: Homo sapiens (Human); More
• Total number of polymer chains: 1
• Total formula weight: 42513.55

Authors

Livnah, O.,Eitan-Wexler, M.,Vinograd, N. (deposition date: 2019-03-10, release date: 2020-04-01, Last modification date: 2020-07-29)

• Primary citation: Gur-Arie, L.,Eitan-Wexler, M.,Weinberger, N.,Rosenshine, I.,Livnah, O.; The bacterial metalloprotease NleD selectively cleaves mitogen-activated protein kinases that have high flexibility in their activation loop.; J.Biol.Chem., 295:9409-9420, 2020; PubMed: 32404367; DOI: 10.1074/jbc.RA120.013590

Experimental method

X-RAY DIFFRACTION (1.66 Å)