6QYX
p38(alpha) MAP kinase with the activation loop of ERK2
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A | Mitogen-activated protein kinase 14,Mitogen-activated protein kinase 1,Mitogen-activated protein kinase 14 | polymer | 366 | 41982.9 | 1 | UniProt (Q16539) UniProt (D2CIU1) Pfam (PF00069) In PDB | Homo sapiens (Human) | MAPK 14,Cytokine suppressive anti-inflammatory drug-binding protein,CSBP,MAP kinase MXI2,MAX-interacting protein 2,Mitogen-activated protein kinase p38 alpha,MAP kinase p38 alpha,Stress-activated protein kinase 2a,SAPK2a,MAPK 14,Cytokine suppressive anti-inflammatory drug-binding protein,CSBP,MAP kinase MXI2,MAX-interacting protein 2,Mitogen-activated protein kinase p38 alpha,MAP kinase p38 alpha,Stress-activated protein kinase 2a,SAPK2a |
2 | A | octyl beta-D-glucopyranoside | non-polymer | 292.4 | 1 | Chemie (BOG) | |||
3 | A | 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID | non-polymer | 238.3 | 1 | Chemie (EPE) | |||
4 | water | water | 18.0 | 204 | Chemie (HOH) |
Sequence modifications
A: 1 - 172 (UniProt: Q16539)
A: 173 - 189 (UniProt: D2CIU1)
A: 190 - 366 (UniProt: Q16539)
PDB | External Database | Details |
---|---|---|
Cys 167 | Leu 167 | conflict |
A: 190 - 366 (UniProt: Q16539)
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 1 |
Total formula weight | 41982.9 | |
Non-Polymers* | Number of molecules | 2 |
Total formula weight | 530.7 | |
All* | Total formula weight | 42513.5 |