8EFJ

A structural study of selectivity mechanisms for JNK3 and p38 alpha with indazole scaffold probing compounds

Summary for 8EFJ

• Entry DOI: 10.2210/pdb8efj/pdb
• Descriptor: Mitogen-activated protein kinase 14, octyl beta-D-glucopyranoside, (4P)-4-[5-(2-chloro-6-fluoroanilino)-6-(methoxymethyl)-1H-indazol-1-yl]-N-methylthiophene-2-carboxamide, ... (4 entities in total)
• Functional Keywords: c-jun terminal kinase 3, jnk3, p38 alpha, kinase, selectivity, transferase
• Biological source: Mus musculus (house mouse)
• Total number of polymer chains: 1
• Total formula weight: 43267.76

Authors

Park, H.,Feng, Y. (deposition date: 2022-09-08, release date: 2023-09-20)

• Primary citation: Park, H.,Feng, Y.; A structural study of selectivity mechanisms for JNK3 and p38 alpha with indazole scaffold probing compounds; To Be Published,

Experimental method

X-RAY DIFFRACTION (2.31 Å)