PDB: 17012 件ウェブページステータス検索Chemie searchBIRD

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5GY9	Crystal structure of ENZbleach xylanase A74C+G84C mutant 分子名称: Endo-1,4-beta-xylanase 著者 Chitnumsub, P, Jaruwat, A, Boonyapakorn, K. 登録日 2016-09-22 公開日 2017-08-30 最終更新日 2023-11-08 実験手法 X-RAY DIFFRACTION (1.94 Å) 主引用文献 Structure-based protein engineering for thermostable and alkaliphilic enhancement of endo-beta-1,4-xylanase for applications in pulp bleaching J. Biotechnol., 259, 2017
5GYF	Crystal structure of ENZbleach xylanase T28C+T60C+L59F mutant 分子名称: Endo-1,4-beta-xylanase 著者 Chitnumsub, P, Jaruwat, A, Boonyapakorn, K. 登録日 2016-09-22 公開日 2017-08-30 最終更新日 2023-11-08 実験手法 X-RAY DIFFRACTION (1.94 Å) 主引用文献 Structure-based protein engineering for thermostable and alkaliphilic enhancement of endo-beta-1,4-xylanase for applications in pulp bleaching J. Biotechnol., 259, 2017
2KNP	Isolation and characterization of peptides from Momordica cochinchinensis seeds. 分子名称: MCoCC-1 著者 Daly, N.L, Chan, L. 登録日 2009-08-30 公開日 2009-11-10 最終更新日 2022-03-16 実験手法 SOLUTION NMR 主引用文献 Isolation and characterization of peptides from Momordica cochinchinensis seeds. J.Nat.Prod., 72, 2009
5E58	Crystal Structure Of Cytochrome P450 2B35 from Desert Woodrat Neotoma Lepida in complex with 4-(4-chlorophenyl)imidazole 分子名称: 4-(4-CHLOROPHENYL)IMIDAZOLE, 5-CYCLOHEXYL-1-PENTYL-BETA-D-MALTOSIDE, Cytochrome P450 family 2 subfamily B, ... 著者 Shah, M.B, Stout, C.D, Halpert, J.R. 登録日 2015-10-08 公開日 2016-02-10 最終更新日 2023-09-27 実験手法 X-RAY DIFFRACTION (2.4 Å) 主引用文献 Structure-Function Analysis of Mammalian CYP2B Enzymes Using 7-Substituted Coumarin Derivatives as Probes: Utility of Crystal Structures and Molecular Modeling in Understanding Xenobiotic Metabolism. Mol.Pharmacol., 89, 2016
5E7R	Crystal structure of TL10-81 bound to TAK1-TAB1 分子名称: 2-chloro-N-{2-[(5-chloro-2-{[4-(4-methylpiperazin-1-yl)phenyl]amino}pyrimidin-4-yl)oxy]phenyl}acetamide, TAK1 kinase - TAB1 chimera fusion protein 著者 Gurbani, D, Hunter, J.C, Tan, L, Chen, Z, Westover, K.D. 登録日 2015-10-13 公開日 2016-09-21 最終更新日 2023-09-27 実験手法 X-RAY DIFFRACTION (2.11 Å) 主引用文献 Structure-guided development of covalent TAK1 inhibitors. Bioorg. Med. Chem., 25, 2017
5EAF	Saccharomyces cerevisiae CYP51 complexed with the plant pathogen inhibitor Fluquinconazole 分子名称: 3-(2,4-dichlorophenyl)-6-fluoranyl-2-(1,2,4-triazol-1-yl)quinazolin-4-one, Lanosterol 14-alpha demethylase, PROTOPORPHYRIN IX CONTAINING FE 著者 Tyndall, J.D.A, Sabherwal, M, Sagatova, A.A, Keniya, M.V, Wilson, R.K, Woods, M.V, Monk, B.C. 登録日 2015-10-16 公開日 2016-02-10 最終更新日 2023-09-27 実験手法 X-RAY DIFFRACTION (2.65 Å) 主引用文献 Structural and Functional Elucidation of Yeast Lanosterol 14 alpha-Demethylase in Complex with Agrochemical Antifungals. PLoS ONE, 11, 2016
5EAB	Saccharomyces cerevisiae CYP51 complexed with the plant pathogen inhibitor S-tebuconazole 分子名称: (3~{S})-1-(4-chlorophenyl)-4,4-dimethyl-3-(1,2,4-triazol-1-ylmethyl)pentan-3-ol, Lanosterol 14-alpha demethylase, PROTOPORPHYRIN IX CONTAINING FE 著者 Tyndall, J.D.A, Sabherwal, M, Sagatova, A.A, Keniya, M.V, Wilson, R.K, Woods, M.V, Monk, B.C. 登録日 2015-10-16 公開日 2016-02-10 最終更新日 2023-09-27 実験手法 X-RAY DIFFRACTION (2.6 Å) 主引用文献 Structural and Functional Elucidation of Yeast Lanosterol 14 alpha-Demethylase in Complex with Agrochemical Antifungals. PLoS ONE, 11, 2016
2H1O	Structure of FitAB bound to IR36 DNA fragment 分子名称: IR36-strand 1, IR36-strand 2, Trafficking protein A, ... 著者 Mattison, K, Wilbur, J.S, So, M, Brennan, R.G. 登録日 2006-05-16 公開日 2006-09-26 最終更新日 2023-08-30 実験手法 X-RAY DIFFRACTION (3 Å) 主引用文献 Structure of FitAB from Neisseria gonorrhoeae bound to DNA reveals a tetramer of toxin-antitoxin heterodimers containing pin domains and ribbon-helix-helix motifs. J.Biol.Chem., 281, 2006
5EKP	Structure of the polyisoprenyl-phosphate glycosyltransferase GtrB (WT) 分子名称: MAGNESIUM ION, URIDINE-5'-DIPHOSPHATE, Uncharacterized glycosyltransferase sll0501 著者 Ardiccioni, C, Clarke, O.B, Tomasek, D, Banerjee, S, Rajashankar, K.R, Liu, Q, Shapiro, L, Mancia, F, New York Consortium on Membrane Protein Structure (NYCOMPS) 登録日 2015-11-03 公開日 2016-01-06 最終更新日 2024-03-06 実験手法 X-RAY DIFFRACTION (3.194 Å) 主引用文献 Structure of the polyisoprenyl-phosphate glycosyltransferase GtrB and insights into the mechanism of catalysis. Nat Commun, 7, 2016
5ESG	Saccharomyces cerevisiae CYP51 (Lanosterol 14-alpha demethylase) G73E mutant complexed with itraconazole 分子名称: 2-[(2R)-butan-2-yl]-4-{4-[4-(4-{[(2R,4S)-2-(2,4-dichlorophenyl)-2-(1H-1,2,4-triazol-1-ylmethyl)-1,3-dioxolan-4-yl]methoxy}phenyl)piperazin-1-yl]phenyl}-2,4-dihydro-3H-1,2,4-triazol-3-one, Lanosterol 14-alpha demethylase, PROTOPORPHYRIN IX CONTAINING FE 著者 Sagatova, A, Keniya, M.V, Wilson, R.K, Sabherwal, M, Tyndall, J.D.A, Monk, B.C. 登録日 2015-11-16 公開日 2016-11-23 最終更新日 2023-09-27 実験手法 X-RAY DIFFRACTION (1.981 Å) 主引用文献 Impact of Homologous Resistance Mutations from Pathogenic Yeast on Saccharomyces cerevisiae Lanosterol 14 alpha-Demethylase. Antimicrob.Agents Chemother., 62, 2018
2H9S	Crystal Structure of Homo-DNA and Nature's Choice of Pentose over Hexose in the Genetic System 分子名称: 5'-D(*(XCT)P*(XGU)P*(XAD)P*(XAD)P*(XTH)P*(XTH)P*(XCT)P*(XGU))-3', MAGNESIUM ION 著者 Egli, M, Pallan, P.S. 登録日 2006-06-11 公開日 2006-12-12 最終更新日 2024-02-14 実験手法 X-RAY DIFFRACTION (1.75 Å) 主引用文献 Crystal structure of homo-DNA and nature's choice of pentose over hexose in the genetic system. J.Am.Chem.Soc., 128, 2006
5EMS	Crystal Structure of an iodinated insulin analog 分子名称: CHLORIDE ION, Insulin, PHENOL, ... 著者 Lawrence, M.C, Pandyarajan, V, Wan, Z, Weiss, M.A. 登録日 2015-11-06 公開日 2016-11-16 最終更新日 2023-11-15 実験手法 X-RAY DIFFRACTION (2.3 Å) 主引用文献 Extending Halogen-based Medicinal Chemistry to Proteins: IODO-INSULIN AS A CASE STUDY. J. Biol. Chem., 291, 2016
5ENK	Compound 18 分子名称: (4~{S},6~{S})-4-[2,4-bis(fluoranyl)-5-pyrimidin-5-yl-phenyl]-6-(3,5-dimethyl-1,2-oxazol-4-yl)-4-methyl-5,6-dihydro-1,3-thiazin-2-amine, Beta-secretase 1, GLYCEROL, ... 著者 Lewis, H.A. 登録日 2015-11-09 公開日 2016-07-06 最終更新日 2024-03-06 実験手法 X-RAY DIFFRACTION (2.11 Å) 主引用文献 Targeting the BACE1 Active Site Flap Leads to a Potent Inhibitor That Elicits Robust Brain A beta Reduction in Rodents. Acs Med.Chem.Lett., 7, 2016
5DLY	Crystal structure of the plantazolicin methyltransferase BamL in complex with monoazolic desmethylPZN analog and SAH 分子名称: S-ADENOSYL-L-HOMOCYSTEINE, plantazolicin methyltransferase BamL, prop-2-en-1-yl 2-[(1S)-1-amino-4-carbamimidamidobutyl]-1,3-thiazole-4-carboxylate 著者 Hao, Y, Nair, S.K. 登録日 2015-09-07 公開日 2015-09-30 最終更新日 2024-03-06 実験手法 X-RAY DIFFRACTION (1.5 Å) 主引用文献 Insights into methyltransferase specificity and bioactivity of derivatives of the antibiotic plantazolicin. ACS Chem. Biol., 10, 2015
5DM1	Crystal structure of the plantazolicin methyltransferase BpumL in complex with monoazolic desmethylPZN analog and SAH 分子名称: GLYCEROL, Methyltransferase domain family, S-ADENOSYL-L-HOMOCYSTEINE, ... 著者 Hao, Y, Nair, S.K. 登録日 2015-09-07 公開日 2015-09-23 最終更新日 2024-03-06 実験手法 X-RAY DIFFRACTION (1.8 Å) 主引用文献 Insights into methyltransferase specificity and bioactivity of derivatives of the antibiotic plantazolicin. Acs Chem.Biol., 10, 2015
2GSS	HUMAN GLUTATHIONE S-TRANSFERASE P1-1 IN COMPLEX WITH ETHACRYNIC ACID 分子名称: 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, ETHACRYNIC ACID, GLUTATHIONE S-TRANSFERASE P1-1, ... 著者 Oakley, A.J, Rossjohn, J, Parker, M.W. 登録日 1996-10-29 公開日 1997-11-12 最終更新日 2024-05-29 実験手法 X-RAY DIFFRACTION (1.9 Å) 主引用文献 The three-dimensional structure of the human Pi class glutathione transferase P1-1 in complex with the inhibitor ethacrynic acid and its glutathione conjugate. Biochemistry, 36, 1997
5ESH	Saccharomyces cerevisiae CYP51 (Lanosterol 14-alpha demethylase) G73W mutant in complex with itraconazole 分子名称: 2-[(2R)-butan-2-yl]-4-{4-[4-(4-{[(2R,4S)-2-(2,4-dichlorophenyl)-2-(1H-1,2,4-triazol-1-ylmethyl)-1,3-dioxolan-4-yl]methoxy}phenyl)piperazin-1-yl]phenyl}-2,4-dihydro-3H-1,2,4-triazol-3-one, Lanosterol 14-alpha demethylase, PROTOPORPHYRIN IX CONTAINING FE 著者 Sagatova, A, Keniya, M.V, Wilson, R.K, Sabherwal, M, Tyndall, J.D.A, Monk, B.C. 登録日 2015-11-16 公開日 2016-11-23 最終更新日 2023-09-27 実験手法 X-RAY DIFFRACTION (2.15 Å) 主引用文献 Impact of Homologous Resistance Mutations from Pathogenic Yeast on Saccharomyces cerevisiae Lanosterol 14 alpha-Demethylase. Antimicrob.Agents Chemother., 62, 2018
5ESJ	Saccharomyces cerevisiae CYP51 (Lanosterol 14-alpha demethylase) G464S mutant complexed with fluconazole 分子名称: 2-(2,4-DIFLUOROPHENYL)-1,3-DI(1H-1,2,4-TRIAZOL-1-YL)PROPAN-2-OL, Lanosterol 14-alpha demethylase, PROTOPORPHYRIN IX CONTAINING FE 著者 Sagatova, A, Keniya, M.V, Wilson, R.K, Sabherwal, M, Tyndall, J.D.A, Monk, B.C. 登録日 2015-11-16 公開日 2016-11-23 最終更新日 2023-09-27 実験手法 X-RAY DIFFRACTION (2.15 Å) 主引用文献 Impact of Homologous Resistance Mutations from Pathogenic Yeast on Saccharomyces cerevisiae Lanosterol 14 alpha-Demethylase. Antimicrob.Agents Chemother., 62, 2018
5ESK	Saccharomyces cerevisiae CYP51 (Lanosterol 14-alpha demethylase) G464S mutant complexed with itraconazole 分子名称: 2-[(2R)-butan-2-yl]-4-{4-[4-(4-{[(2R,4S)-2-(2,4-dichlorophenyl)-2-(1H-1,2,4-triazol-1-ylmethyl)-1,3-dioxolan-4-yl]methoxy}phenyl)piperazin-1-yl]phenyl}-2,4-dihydro-3H-1,2,4-triazol-3-one, Lanosterol 14-alpha demethylase, PROTOPORPHYRIN IX CONTAINING FE 著者 Sagatova, A, Keniya, M.V, Wilson, R.K, Sabherwal, M, Tyndall, J.D.A, Monk, B.C. 登録日 2015-11-16 公開日 2016-11-23 最終更新日 2023-09-27 実験手法 X-RAY DIFFRACTION (2.24 Å) 主引用文献 Impact of Homologous Resistance Mutations from Pathogenic Yeast on Saccharomyces cerevisiae Lanosterol 14 alpha-Demethylase. Antimicrob.Agents Chemother., 62, 2018
2GZ9	Structure-Based Drug Design and Structural Biology Study of Novel Nonpeptide Inhibitors of SARS-CoV Main Protease 分子名称: Replicase polyprotein 1ab 著者 Lu, I.L, Wu, S.Y. 登録日 2006-05-11 公開日 2006-08-29 最終更新日 2023-10-25 実験手法 X-RAY DIFFRACTION (2.17 Å) 主引用文献 Structure-Based Drug Design and Structural Biology Study of Novel Nonpeptide Inhibitors of Severe Acute Respiratory Syndrome Coronavirus Main Protease J.Med.Chem., 49, 2006
5EZ8	A de novo designed heptameric coiled coil CC-Hept-I-C-I 分子名称: CC-Hept-I-C-I 著者 Burton, A.J, Brady, R.L, Woolfson, D.N. 登録日 2015-11-26 公開日 2016-07-06 最終更新日 2024-01-10 実験手法 X-RAY DIFFRACTION (1.95 Å) 主引用文献 Installing hydrolytic activity into a completely de novo protein framework. Nat.Chem., 8, 2016
2H1C	Crystal Structure of FitAcB from Neisseria gonorrhoeae 分子名称: ACETATE ION, MAGNESIUM ION, SULFATE ION, ... 著者 Mattison, K, Wilbur, J.S, So, M, Brennan, R.G. 登録日 2006-05-16 公開日 2006-09-26 最終更新日 2024-02-14 実験手法 X-RAY DIFFRACTION (1.8 Å) 主引用文献 Structure of FitAB from Neisseria gonorrhoeae bound to DNA reveals a tetramer of toxin-antitoxin heterodimers containing pin domains and ribbon-helix-helix motifs. J.Biol.Chem., 281, 2006
5H7N	Crystal structure of human NLRP12-PYD with a MBP tag 分子名称: 1,2-ETHANEDIOL, DI(HYDROXYETHYL)ETHER, NLRP12-PYD with MBP tag, ... 著者 Jin, T.C, Xiao, T.S. 登録日 2016-11-19 公開日 2017-02-15 最終更新日 2023-11-08 実験手法 X-RAY DIFFRACTION (1.849 Å) 主引用文献 Design of an expression system to enhance MBP-mediated crystallization Sci Rep, 7, 2017
2GJ0	Cycloviolacin O14 分子名称: Cycloviolacin O14 著者 Ireland, D.C, Colgrave, M.L, Craik, D.J. 登録日 2006-03-30 公開日 2006-04-11 最終更新日 2022-03-09 実験手法 SOLUTION NMR 主引用文献 A novel suite of cyclotides from Viola odorata: sequence variation and the implications for structure, function and stability Biochem.J., 400, 2006
5D5P	HcgB from Methanococcus maripaludis 分子名称: HcgB 著者 Fujishiro, T, Ermler, U, Shima, S. 登録日 2015-08-11 公開日 2016-10-26 最終更新日 2024-01-10 実験手法 X-RAY DIFFRACTION (1.7 Å) 主引用文献 Towards artificial methanogenesis: biosynthesis of the [Fe]-hydrogenase cofactor and characterization of the semi-synthetic hydrogenase. Faraday Discuss., 198, 2017

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