2GSS

HUMAN GLUTATHIONE S-TRANSFERASE P1-1 IN COMPLEX WITH ETHACRYNIC ACID

Summary for 2GSS

Entry DOI	10.2210/pdb2gss/pdb
Descriptor	GLUTATHIONE S-TRANSFERASE P1-1, SULFATE ION, ETHACRYNIC ACID, ... (5 entities in total)
Functional Keywords	glutathione, transferase, pi, detoxification, ethacrynic acid
Biological source	Homo sapiens (human)
Total number of polymer chains	2
Total formula weight	47781.19
Authors	Oakley, A.J.,Rossjohn, J.,Parker, M.W. (deposition date: 1996-10-29, release date: 1997-11-12, Last modification date: 2023-08-09)
Primary citation	Oakley, A.J.,Rossjohn, J.,Lo Bello, M.,Caccuri, A.M.,Federici, G.,Parker, M.W. The three-dimensional structure of the human Pi class glutathione transferase P1-1 in complex with the inhibitor ethacrynic acid and its glutathione conjugate. Biochemistry, 36:576-585, 1997 Cited by PubMed: 9012673 DOI: 10.1021/bi962316i PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.9 Å)

Structure validation