5DLY

Crystal structure of the plantazolicin methyltransferase BamL in complex with monoazolic desmethylPZN analog and SAH

Summary for 5DLY

Entry DOI	10.2210/pdb5dly/pdb
Related	5DLY 5DM1 5DM2 5DM4
Descriptor	plantazolicin methyltransferase BamL, prop-2-en-1-yl 2-[(1S)-1-amino-4-carbamimidamidobutyl]-1,3-thiazole-4-carboxylate, S-ADENOSYL-L-HOMOCYSTEINE, ... (4 entities in total)
Functional Keywords	plantazolicin, n-methyltransferase, transferase-transferase inhibitor complex, transferase/transferase inhibitor
Biological source	Bacillus amyloliquefaciens subsp. plantarum (strain DSM 23117 / BGSC 10A6 / FZB42)
Total number of polymer chains	1
Total formula weight	31014.04
Authors	Hao, Y.,Nair, S.K. (deposition date: 2015-09-07, release date: 2015-09-30, Last modification date: 2024-03-06)
Primary citation	Hao, Y.,Blair, P.M.,Sharma, A.,Mitchell, D.A.,Nair, S.K. Insights into methyltransferase specificity and bioactivity of derivatives of the antibiotic plantazolicin. ACS Chem. Biol., 10:1209-1216, 2015 Cited by PubMed: 25635336 DOI: 10.1021/cb501042a PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.5 Å)

Structure validation