5DM4

Crystal structure of the plantazolicin methyltransferase BpumL in complex with pentazolic desmethylPZN analog and SAH

Summary for 5DM4

Entry DOI	10.2210/pdb5dm4/pdb
Related	5DLY 5DM1 5DM2
Descriptor	Methyltransferase domain family, S-ADENOSYL-L-HOMOCYSTEINE, GLYCEROL, ... (5 entities in total)
Functional Keywords	n-methyltransferase, plantazolicin, pentazolic desmethylpzn analog, transferase-transferase inhibitor complex, transferase/transferase inhibitor
Biological source	Bacillus pumilus ATCC 7061
Total number of polymer chains	1
Total formula weight	31415.75
Authors	Hao, Y.,Nair, S.K. (deposition date: 2015-09-07, release date: 2015-09-23, Last modification date: 2024-03-13)
Primary citation	Hao, Y.,Blair, P.M.,Sharma, A.,Mitchell, D.A.,Nair, S.K. Insights into methyltransferase specificity and bioactivity of derivatives of the antibiotic plantazolicin. Acs Chem.Biol., 10:1209-1216, 2015 Cited by PubMed: 25635336 DOI: 10.1021/cb501042a PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.75 Å)

Structure validation