PDB: 990 件ウェブページステータス検索Chemie searchBIRD

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3RGF	Crystal Structure of human CDK8/CycC 分子名称: 1,2-ETHANEDIOL, 4-{4-[({[4-CHLORO-3-(TRIFLUOROMETHYL)PHENYL]AMINO}CARBONYL)AMINO]PHENOXY}-N-METHYLPYRIDINE-2-CARBOXAMIDE, Cyclin-C, ... 著者 Schneider, E.V, Boettcher, J, Blaesse, M, Huber, R, Maskos, K. 登録日 2011-04-08 公開日 2011-08-10 最終更新日 2023-09-13 実験手法 X-RAY DIFFRACTION (2.2 Å) 主引用文献 The Structure of CDK8/CycC Implicates Specificity in the CDK/Cyclin Family and Reveals Interaction with a Deep Pocket Binder. J.Mol.Biol., 412, 2011
8A8Y	Structure of truncated 1-deoxy-D-xylulose 5-phosphate synthase (DXS) from Klebsiella pneumoniae 分子名称: 1-deoxy-D-xylulose-5-phosphate synthase 著者 Adam, S, Hirsch, A. 登録日 2022-06-24 公開日 2023-07-05 最終更新日 2024-02-07 実験手法 X-RAY DIFFRACTION (2.10000443 Å) 主引用文献 Structure of truncated 1-deoxy-D-xylulose 5-phosphate synthase (DXS) from Klebsiella pneumoniae To Be Published
8A9C	Structure of truncated 1-deoxy-D-xylulose 5-phosphate synthase (DXS) from Klebsiella pneumoniae in complex with cofactor TPP 分子名称: 1-deoxy-D-xylulose-5-phosphate synthase, MAGNESIUM ION, THIAMINE DIPHOSPHATE 著者 Adam, S, Hirsch, A. 登録日 2022-06-28 公開日 2023-07-12 最終更新日 2024-02-07 実験手法 X-RAY DIFFRACTION (1.8 Å) 主引用文献 Structure of truncated 1-deoxy-D-xylulose 5-phosphate synthase (DXS) from Klebsiella pneumoniae in complex with cofactor TPP To Be Published
6EMF	Crystal structure of Rrp1 from Chaetomium thermophilum in space group C2 分子名称: 1,2-ETHANEDIOL, G0S4M2, PROLINE 著者 Ahmed, Y.L, Sinning, I. 登録日 2017-10-02 公開日 2017-12-27 最終更新日 2024-05-08 実験手法 X-RAY DIFFRACTION (2.65 Å) 主引用文献 Visualizing the Assembly Pathway of Nucleolar Pre-60S Ribosomes. Cell, 171, 2017
6EN7	Crystal structure of the ribosome assembly factor Nsa1 分子名称: Ribosome biogenesis protein NSA1 著者 Altegoer, F, Bange, G. 登録日 2017-10-04 公開日 2017-12-27 最終更新日 2024-01-17 実験手法 X-RAY DIFFRACTION (2.403 Å) 主引用文献 Visualizing the Assembly Pathway of Nucleolar Pre-60S Ribosomes. Cell, 171, 2017
6EMG	Crystal structure of Rrp1 from Chaetomium thermophilum in space group P6322 分子名称: 1,2-ETHANEDIOL, 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, G0S4M2, ... 著者 Ahmed, Y.L, Sinning, I. 登録日 2017-10-02 公開日 2017-12-27 最終更新日 2024-05-08 実験手法 X-RAY DIFFRACTION (2.24 Å) 主引用文献 Visualizing the Assembly Pathway of Nucleolar Pre-60S Ribosomes. Cell, 171, 2017
7MN6	Structure of the HER2 S310F/HER3/NRG1b Heterodimer Extracellular Domain 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Isoform 6 of Pro-neuregulin-1, ... 著者 Diwanji, D, Trenker, R, Verba, K.A, Jura, N. 登録日 2021-04-30 公開日 2021-10-27 最終更新日 2021-12-22 実験手法 ELECTRON MICROSCOPY (3.09 Å) 主引用文献 Structures of the HER2-HER3-NRG1 beta complex reveal a dynamic dimer interface. Nature, 600, 2021
5MUB	ACC1 Fab fragment in complex with citrullinated C1 epitope of CII (CG05) 分子名称: ACC1 Fab fragment heavy chain, ACC1 Fab fragment light chain, triple-helical peptide containing the citrullinated C1 epitope of collagen type II,Collagen alpha-1(II) chain,triple-helical peptide containing the citrullinated C1 epitope of collagen type II 著者 Dobritzsch, D, Holmdahl, R, Ge, C. 登録日 2017-01-13 公開日 2017-07-19 最終更新日 2024-01-17 実験手法 X-RAY DIFFRACTION (3.1 Å) 主引用文献 Anti-citrullinated protein antibodies cause arthritis by cross-reactivity to joint cartilage. JCI Insight, 2, 2017
5MU2	ACC1 Fab fragment in complex with CII583-591 (CG10) 分子名称: ACC1 Fab fragment heavy chain, ACC1 Fab fragment light chain, synthetic peptide containing the CII583-591 epitope of collagen type II 著者 Dobritzsch, D, Holmdahl, R, Ge, C. 登録日 2017-01-12 公開日 2017-07-19 最終更新日 2024-01-17 実験手法 X-RAY DIFFRACTION (2.7 Å) 主引用文献 Anti-citrullinated protein antibodies cause arthritis by cross-reactivity to joint cartilage. JCI Insight, 2, 2017
5MU0	ACC1 Fab fragment in complex with citrullinated C1 epitope of CII (IA03) 分子名称: IA03 peptide containing the citrullinated C1 epitope of collagen type II,Collagen alpha-1(II) chain,IA03 peptide containing the citrullinated C1 epitope of collagen type II, heavy chain of ACC1 antibody Fab fragment, light chain of ACC1 antibody Fab fragment 著者 Dobritzsch, D, Holmdahl, R, Ge, C. 登録日 2017-01-11 公開日 2017-07-19 最終更新日 2024-01-17 実験手法 X-RAY DIFFRACTION (2.7 Å) 主引用文献 Anti-citrullinated protein antibodies cause arthritis by cross-reactivity to joint cartilage. JCI Insight, 2, 2017
5MV3	ACC1 Fab fragment in complex with CII583-591 (CG10) 分子名称: heavy chain of ACC1 Fab fragment, light chain of ACC1 Fab fragment, synthetic peptide containing the CII583-591 epitope of collagen type II,Collagen alpha-1(II) chain,synthetic peptide containing the CII583-591 epitope of collagen type II, 著者 Dobritzsch, D, Holmdahl, R, Ge, C. 登録日 2017-01-15 公開日 2017-07-19 最終更新日 2024-01-17 実験手法 X-RAY DIFFRACTION (2.95 Å) 主引用文献 Anti-citrullinated protein antibodies cause arthritis by cross-reactivity to joint cartilage. JCI Insight, 2, 2017
5NVN	Crystal structure of the human 4EHP-4E-BP1 complex 分子名称: Eukaryotic translation initiation factor 4E type 2, Eukaryotic translation initiation factor 4E-binding protein 1, FORMIC ACID 著者 Peter, D, Sandmeir, F, Valkov, E. 登録日 2017-05-04 公開日 2017-07-26 最終更新日 2024-01-17 実験手法 X-RAY DIFFRACTION (1.9 Å) 主引用文献 GIGYF1/2 proteins use auxiliary sequences to selectively bind to 4EHP and repress target mRNA expression. Genes Dev., 31, 2017
5MV4	ACC1 Fab fragment in complex with citrullinated CII616-639 epitope of collagen type II (ptm23) 分子名称: ACC1 antibody Fab fragment, heavy chain, light chain, ... 著者 Dobritzsch, D, Holmdahl, R, Ge, C. 登録日 2017-01-15 公開日 2017-07-19 最終更新日 2024-01-17 実験手法 X-RAY DIFFRACTION (2.9 Å) 主引用文献 Anti-citrullinated protein antibodies cause arthritis by cross-reactivity to joint cartilage. JCI Insight, 2, 2017
6G4G	Full length ectodomain of ectonucleotide phosphodiesterase/pyrophosphatase-3 (NPP3) including the SMB domains but with a partially disordered active site structure 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, ... 著者 Dohler, C, Zebisch, M, Strater, N. 登録日 2018-03-27 公開日 2018-11-07 最終更新日 2024-01-17 実験手法 X-RAY DIFFRACTION (2.8 Å) 主引用文献 Crystallization of ectonucleotide phosphodiesterase/pyrophosphatase-3 and orientation of the SMB domains in the full-length ectodomain. Acta Crystallogr F Struct Biol Commun, 74, 2018
6GEF	X-ray structure of the Yersinia pseudotuberculosis ATPase DotB 分子名称: Type IV secretion system protein DotB 著者 Prevost, M.S, Waksman, G. 登録日 2018-04-26 公開日 2018-05-30 最終更新日 2024-01-17 実験手法 X-RAY DIFFRACTION (2.75 Å) 主引用文献 X-ray crystal structures of the type IVb secretion system DotB ATPases. Protein Sci., 27, 2018
6GEB	X-ray structure of the Legionella pneumophila ATPase DotB 分子名称: DotB, PHOSPHATE ION 著者 Prevost, M.S, Waksman, G. 登録日 2018-04-26 公開日 2018-05-30 最終更新日 2024-01-17 実験手法 X-RAY DIFFRACTION (3.19 Å) 主引用文献 X-ray crystal structures of the type IVb secretion system DotB ATPases. Protein Sci., 27, 2018
6T41	CDK8/Cyclin C in complex with N-(4-chlorobenzyl)isoquinolin-4-amine 分子名称: 1,2-ETHANEDIOL, Cyclin-C, Cyclin-dependent kinase 8, ... 著者 Schneider, E.V, Maskos, K, Huber, R, Kuhn, C.-D. 登録日 2019-10-11 公開日 2020-01-01 最終更新日 2024-01-24 実験手法 X-RAY DIFFRACTION (2.45 Å) 主引用文献 A precisely positioned MED12 activation helix stimulates CDK8 kinase activity. Proc.Natl.Acad.Sci.USA, 117, 2020
6TPA	CDK8/CyclinC in complex with drug ETP-50775 分子名称: (2~{R})-butane-1,2-diol, 1-[4-chloranyl-3-(trifluoromethyl)phenyl]-3-(5-oxidanylidene-6-pyridin-4-yl-pyrido[2,3-b][1,5]benzoxazepin-9-yl)urea, Cyclin-C, ... 著者 Munoz, I.G, Pastor, J, Martinez, S. 登録日 2019-12-12 公開日 2020-11-18 最終更新日 2024-01-24 実験手法 X-RAY DIFFRACTION (2.8 Å) 主引用文献 Pyrido[2,3-b][1,5]benzoxazepin-5(6H)-one derivatives as CDK8 inhibitors. Eur.J.Med.Chem., 201, 2020
1G6O	CRYSTAL STRUCTURE OF THE HELICOBACTER PYLORI ATPASE, HP0525, IN COMPLEX WITH ADP 分子名称: ADENOSINE-5'-DIPHOSPHATE, CAG-ALPHA, DI(HYDROXYETHYL)ETHER 著者 Yeo, H.J, Savvides, S.N, Herr, A.B, Lanka, E, Waksman, G, Midwest Center for Structural Genomics (MCSG) 登録日 2000-11-07 公開日 2001-01-24 最終更新日 2011-07-13 実験手法 X-RAY DIFFRACTION (2.5 Å) 主引用文献 Crystal structure of the hexameric traffic ATPase of the Helicobacter pylori type IV secretion system. Mol.Cell, 6, 2000
1FV1	STRUCTURAL BASIS FOR THE BINDING OF AN IMMUNODOMINANT PEPTIDE FROM MYELIN BASIC PROTEIN IN DIFFERENT REGISTERS BY TWO HLA-DR2 ALLELES 分子名称: GLYCEROL, MAJOR HISTOCOMPATIBILITY COMPLEX ALPHA CHAIN, MAJOR HISTOCOMPATIBILITY COMPLEX BETA CHAIN, ... 著者 Li, H, Mariuzza, A.R, Li, Y, Martin, R. 登録日 2000-09-18 公開日 2000-09-27 最終更新日 2011-07-13 実験手法 X-RAY DIFFRACTION (1.9 Å) 主引用文献 Structural basis for the binding of an immunodominant peptide from myelin basic protein in different registers by two HLA-DR2 proteins. J.Mol.Biol., 304, 2000
2MZQ	NMR structure of the RRM3 domain of Gbp2 分子名称: Single-strand telomeric DNA-binding protein GBP2 著者 Martinez-Lumbreras, S, Seraphin, B, Perez-Canadillas, J. 登録日 2015-02-23 公開日 2015-12-02 最終更新日 2024-05-15 実験手法 SOLUTION NMR 主引用文献 Gbp2 interacts with THO/TREX through a novel type of RRM domain. Nucleic Acids Res., 44, 2016
2N01	NMR structure of VirB9 C-terminal domain in complex with VirB7 N-terminal domain from Xanthomonas citri's T4SS 分子名称: VirB7 protein, VirB9 protein 著者 Oliveira, L.C, Souza, D.P, Salinas, R.K, Wienk, H, Boelens, R, Farah, S.C. 登録日 2015-03-03 公開日 2015-09-09 最終更新日 2024-05-01 実験手法 SOLUTION NMR 主引用文献 VirB7 and VirB9 Interactions Are Required for the Assembly and Antibacterial Activity of a Type IV Secretion System. Structure, 24, 2016
6ONJ	Crystal structure of PPARgamma ligand binding domain in complex with TRAP220 peptide and agonist rosiglitazone 分子名称: 2,4-THIAZOLIDIINEDIONE, 5-[[4-[2-(METHYL-2-PYRIDINYLAMINO)ETHOXY]PHENYL]METHYL]-(9CL), Mediator of RNA polymerase II transcription subunit 1, ... 著者 Shang, J, Kojetin, D.J. 登録日 2019-04-22 公開日 2020-03-04 最終更新日 2023-10-11 実験手法 X-RAY DIFFRACTION (2.3 Å) 主引用文献 A molecular switch regulating transcriptional repression and activation of PPAR gamma. Nat Commun, 11, 2020
2DYP	Crystal Structure of LILRB2(LIR2/ILT4/CD85d) complexed with HLA-G 分子名称: 9 Mer Peptide From Histone H2A.x, Beta-2-microglobulin, HLA class I histocompatibility antigen, ... 著者 Shiroishi, M, Kuroki, K, Rasubala, L, Kohda, D, Maenaka, K. 登録日 2006-09-15 公開日 2006-11-07 最終更新日 2023-10-25 実験手法 X-RAY DIFFRACTION (2.5 Å) 主引用文献 Structural basis for recognition of the nonclassical MHC molecule HLA-G by the leukocyte Ig-like receptor B2 (LILRB2/LIR2/ILT4/CD85d) Proc.Natl.Acad.Sci.Usa, 103, 2006
2PUU	Crystal structure of p38 complex with 1-(5-tert-Butyl-2-p-tolyl-2H-pyrazol-3-yl)-3-[4-(6-morpholin-4-ylmethyl-pyridin-3-yl)naphthalen-1-yl]urea 分子名称: 5-TERT-BUTYL-2-(4-METHYLPHENYL)-3-{[({4-[6-(MORPHOLIN-4-YLMETHYL)PYRIDIN-3-YL]-1-NAPHTHYL}AMINO)CARBONYL]AMINO}-1H-PYRAZOL-2-IUM, Mitogen-activated protein kinase 14 著者 Qian, K.C. 登録日 2007-05-09 公開日 2008-05-20 最終更新日 2024-02-21 実験手法 X-RAY DIFFRACTION (2.5 Å) 主引用文献 A new class of p38 MAP kinase inhibitors based on the pyrazole-naphthyl urea scaffold To be Published

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