6G4G

Full length ectodomain of ectonucleotide phosphodiesterase/pyrophosphatase-3 (NPP3) including the SMB domains but with a partially disordered active site structure

Summary for 6G4G

• Entry DOI: 10.2210/pdb6g4g/pdb
• Related: 6f2t
• Descriptor: Ectonucleotide pyrophosphatase/phosphodiesterase family member 3, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, ... (4 entities in total)
• Functional Keywords: enzyme, ectonucleotide phosphodiesterase/pyrophosphatase, complex, zinc, smb, pde, hydrolase
• Biological source: Rattus norvegicus (Rat)
• Total number of polymer chains: 4
• Total formula weight: 387204.00

Authors

Dohler, C.,Zebisch, M.,Strater, N. (deposition date: 2018-03-27, release date: 2018-11-07, Last modification date: 2024-01-17)

• Primary citation: Dohler, C.,Zebisch, M.,Krinke, D.,Robitzki, A.,Strater, N.; Crystallization of ectonucleotide phosphodiesterase/pyrophosphatase-3 and orientation of the SMB domains in the full-length ectodomain.; Acta Crystallogr F Struct Biol Commun, 74:696-703, 2018; PubMed: 30387774; DOI: 10.1107/S2053230X18011111

Experimental method

X-RAY DIFFRACTION (2.8 Å)