6D4I
| Crystal Structure of a Fc Fragment of Rhesus macaque (Macaca mulatta) IgG2 | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-alpha-D-mannopyranose-(1-3)-[2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-alpha-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, Fc fragment of IgG2 | 著者 | Gohain, N, Tolbert, W.D, Pazgier, M. | 登録日 | 2018-04-18 | 公開日 | 2019-05-01 | 最終更新日 | 2023-10-04 | 実験手法 | X-RAY DIFFRACTION (2.95 Å) | 主引用文献 | From Rhesus macaque to human: structural evolutionary pathways for immunoglobulin G subclasses. Mabs, 11, 2019
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6KS2
| Structure of anti-Ghrelin receptor antibody | 分子名称: | Fab7881 Heavy Chain (FabH), Fab7881 Light Chain (FabL) | 著者 | Shiimura, Y, Horita, S, Asada, H, Hirata, K, Iwata, S, Kojima, M. | 登録日 | 2019-08-23 | 公開日 | 2020-08-12 | 最終更新日 | 2023-11-22 | 実験手法 | X-RAY DIFFRACTION (1.753 Å) | 主引用文献 | Structure of an antagonist-bound ghrelin receptor reveals possible ghrelin recognition mode. Nat Commun, 11, 2020
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6F2Z
| Structure of a Fc mutant | 分子名称: | Fc fragment of antibody, beta-D-galactopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-alpha-D-mannopyranose-(1-6)-[2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-alpha-D-mannopyranose-(1-3)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[beta-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, beta-D-galactopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-alpha-D-mannopyranose-(1-6)-[alpha-D-mannopyranose-(1-3)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | 著者 | Zhou, A, Li, S. | 登録日 | 2017-11-27 | 公開日 | 2018-12-12 | 最終更新日 | 2023-07-05 | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | 主引用文献 | Structure of Fc mutant in monomeric form To Be Published
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6MWN
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6UGU
| Crystal structure of the Fab fragment of anti-TNFa antibody infliximab (Remicade) in a C-centered orthorhombic crystal form, Lot C | 分子名称: | PF06438179 Fab Heavy Chain, PF06438179 Fab Light Chain | 著者 | Lerch, T.F, Sharpe, P, Mayclin, S.J, Edwards, T.E, Polleck, S, Rouse, J.C, Conlan, H.D. | 登録日 | 2019-09-26 | 公開日 | 2019-11-13 | 最終更新日 | 2023-10-11 | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | 主引用文献 | Crystal Structures of PF-06438179/GP1111, an Infliximab Biosimilar. BioDrugs, 34, 2020
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6UGY
| Crystal structure of the Fc fragment of anti-TNFa antibody infliximab (Remicade) in a primative orthorhombic crystal form, Lot C | 分子名称: | ACETATE ION, Remicade Fc, ZINC ION, ... | 著者 | Mayclin, S.J, Edwards, T.E. | 登録日 | 2019-09-26 | 公開日 | 2019-11-13 | 最終更新日 | 2023-10-11 | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | 主引用文献 | Crystal Structures of PF-06438179/GP1111, an Infliximab Biosimilar. BioDrugs, 34, 2020
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6U9S
| Crystal structure of human CD81 large extracellular loop in complex with 5A6 Fab | 分子名称: | 5A6 FAB Heavy Chain, 5A6 FAB Light Chain, CD81 antigen, ... | 著者 | Susa, K.J, Seegar, T.C.M, Blacklow, S.C.B, Kruse, A.C. | 登録日 | 2019-09-09 | 公開日 | 2020-05-13 | 最終更新日 | 2023-10-11 | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | 主引用文献 | A dynamic interaction between CD19 and the tetraspanin CD81 controls B cell co-receptor trafficking. Elife, 9, 2020
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6UGV
| Crystal structure of the Fab fragment of anti-TNFa antibody infliximab (Remicade) in a I-centered orthorhombic crystal form, Lot C | 分子名称: | 1,2-ETHANEDIOL, Infliximab Fab Heavy Chain, Infliximab Fab Light Chain, ... | 著者 | Lerch, T.F, Sharpe, P, Mayclin, S.J, Edwards, T.E, Polleck, S, Rouse, J.C, Conlan, H.D. | 登録日 | 2019-09-26 | 公開日 | 2019-11-13 | 最終更新日 | 2023-10-11 | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | 主引用文献 | Crystal Structures of PF-06438179/GP1111, an Infliximab Biosimilar. BioDrugs, 34, 2020
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4JVP
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6GHG
| Variable heavy - variable light domain and Fab-arm CrossMabs with charged residue exchanges | 分子名称: | Fab heavy chain, Fab light chain, HEXAETHYLENE GLYCOL, ... | 著者 | Regula, J, Imhof-Jung, S, Molhoj, M, Benz, J, Ehler, A, Bujotzek, A, Schaefer, W, Klein, C. | 登録日 | 2018-05-07 | 公開日 | 2018-09-12 | 最終更新日 | 2018-12-05 | 実験手法 | X-RAY DIFFRACTION (1.88 Å) | 主引用文献 | Variable heavy-variable light domain and Fab-arm CrossMabs with charged residue exchanges to enforce correct light chain assembly. Protein Eng. Des. Sel., 31, 2018
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7KNA
| Localized reconstruction of the H1 A/Michigan/45/2015 ectodomain displayed at the surface of I53_dn5 nanoparticle | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Hemagglutinin,I53_dn5 | 著者 | Acton, O.J, Park, Y.J, Veesler, D, Seattle Structural Genomics Center for Infectious Disease (SSGCID) | 登録日 | 2020-11-04 | 公開日 | 2021-03-31 | 最終更新日 | 2024-05-01 | 実験手法 | ELECTRON MICROSCOPY (3.3 Å) | 主引用文献 | Quadrivalent influenza nanoparticle vaccines induce broad protection. Nature, 592, 2021
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5YHL
| Crystal structure of the human prostaglandin E receptor EP4 in complex with Fab and an antagonist Br-derivative | 分子名称: | 4-[2-[[(2R)-2-(4-bromanylnaphthalen-1-yl)propanoyl]amino]-4-cyano-phenyl]butanoic acid, Heavy chain of Fab fragment, Light chain of Fab fragment, ... | 著者 | Toyoda, Y, Morimoto, K, Suno, R, Horita, S, Iwata, S, Kobayashi, T. | 登録日 | 2017-09-28 | 公開日 | 2018-12-05 | 最終更新日 | 2023-11-22 | 実験手法 | X-RAY DIFFRACTION (4.2 Å) | 主引用文献 | Ligand binding to human prostaglandin E receptor EP4at the lipid-bilayer interface. Nat. Chem. Biol., 15, 2019
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6OYA
| Structure of the Rhodopsin-Transducin-Nanobody Complex | 分子名称: | Camelid antibody VHH fragment, Gt-alpha/Gi1-alpha chimera, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, ... | 著者 | Gao, Y, Hu, H, Ramachandran, S, Erickson, J.W, Cerione, R.A, Skiniotis, G. | 登録日 | 2019-05-14 | 公開日 | 2019-07-24 | 最終更新日 | 2019-12-04 | 実験手法 | ELECTRON MICROSCOPY (3.3 Å) | 主引用文献 | Structures of the Rhodopsin-Transducin Complex: Insights into G-Protein Activation. Mol.Cell, 75, 2019
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5YWY
| Crystal structure of the human prostaglandin E receptor EP4 in complex with Fab and ONO-AE3-208 | 分子名称: | 4-[4-cyano-2-[[(2R)-2-(4-fluoranylnaphthalen-1-yl)propanoyl]amino]phenyl]butanoic acid, Heavy chain of Fab fragment, Light chain of Fab fragment, ... | 著者 | Toyoda, Y, Morimoto, K, Suno, R, Horita, S, Iwata, S, Kobayashi, T. | 登録日 | 2017-11-30 | 公開日 | 2018-12-05 | 最終更新日 | 2018-12-19 | 実験手法 | X-RAY DIFFRACTION (3.2 Å) | 主引用文献 | Ligand binding to human prostaglandin E receptor EP4at the lipid-bilayer interface. Nat. Chem. Biol., 15, 2019
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5DMI
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5FXC
| Crystal structure of glycopeptide 22 in complex with scFv-SM3 | 分子名称: | 1,2-ETHANEDIOL, GLYCOPEPTIDE, SCFV-SM3 | 著者 | Rojas-Ocariz, V, Companon, I, Aydillo, C, Castro-Lopez, J, Jimenez-Barbero, J, Hurtado-Guerrero, R, Avenoza, A, Zurbano, M.M, Corzana, F, Busto, J.H, Peregrina, J.M. | 登録日 | 2016-02-29 | 公開日 | 2016-06-29 | 最終更新日 | 2024-01-10 | 実験手法 | X-RAY DIFFRACTION (2.05 Å) | 主引用文献 | Design of Alpha-S-Glycopeptides Derived from Muc1 with a Flexible and Solvent Exposed Sugar Moiety J.Org.Chem., 81, 2016
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6CE0
| Crystal structure of a HIV-1 clade B tier-3 isolate H078.14 UFO-BG Env trimer in complex with broadly neutralizing Fabs PGT124 and 35O22 at 4.6 Angstrom | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 35O22 Heavy chain, ... | 著者 | Kumar, S, Sarkar, A, Wilson, I.A. | 登録日 | 2018-02-09 | 公開日 | 2018-12-05 | 最終更新日 | 2023-10-04 | 実験手法 | X-RAY DIFFRACTION (4.602 Å) | 主引用文献 | HIV-1 vaccine design through minimizing envelope metastability. Sci Adv, 4, 2018
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7L8P
| Integrin alphaIIbbeta3 in complex with sibrafiban | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, ... | 著者 | Lin, F.-Y, Springer, T.A. | 登録日 | 2020-12-31 | 公開日 | 2022-06-15 | 最終更新日 | 2023-10-25 | 実験手法 | X-RAY DIFFRACTION (2.34995365 Å) | 主引用文献 | A general chemical principle for creating closure-stabilizing integrin inhibitors. Cell, 185, 2022
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7TTZ
| Heterodimeric IgA Fc in complex with Staphylococcus aureus protein SSL7 | 分子名称: | 1,2-ETHANEDIOL, 2-(2-{2-[2-(2-METHOXY-ETHOXY)-ETHOXY]-ETHOXY}-ETHOXY)-ETHANOL, 2-acetamido-2-deoxy-beta-D-glucopyranose, ... | 著者 | Boulanger, M.J, Verstraete, M, Heinkel, F, Escobar, E, Dixit, S, Von Kreudenstein, T.S. | 登録日 | 2022-02-02 | 公開日 | 2023-02-01 | 最終更新日 | 2023-10-25 | 実験手法 | X-RAY DIFFRACTION (2.35 Å) | 主引用文献 | Engineering a pure and stable heterodimeric IgA for the development of multispecific therapeutics. Mabs, 14, 2022
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5WCC
| Crystal structure of the broadly neutralizing Influenza A antibody VRC 315 02-1F07 Fab. | 分子名称: | GLYCEROL, POLYETHYLENE GLYCOL (N=34), SULFATE ION, ... | 著者 | Joyce, M.G, Andrews, S.F, Mascola, J.R, McDermott, A.B, Kwong, P.D. | 登録日 | 2017-06-29 | 公開日 | 2017-12-13 | 最終更新日 | 2023-10-04 | 実験手法 | X-RAY DIFFRACTION (2.461 Å) | 主引用文献 | Preferential induction of cross-group influenza A hemagglutinin stem-specific memory B cells after H7N9 immunization in humans. Sci Immunol, 2, 2017
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8GPK
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7LI8
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7LI7
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7LI6
| apo SERT reconstituted in lipid nanodisc in KCl | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CHLORIDE ION, DECANE, ... | 著者 | Yang, D, Gouaux, E. | 登録日 | 2021-01-26 | 公開日 | 2021-12-15 | 実験手法 | ELECTRON MICROSCOPY (3.5 Å) | 主引用文献 | Illumination of serotonin transporter mechanism and role of the allosteric site. Sci Adv, 7, 2021
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7M2J
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