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PDB: 13 results
6U8K
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BU of 6u8k by Molmil
Crystal structure of hepatitis C virus IRES junction IIIabc in complex with Fab HCV3
Descriptor: Heavy chain of Fab HCV3, JIIIabc RNA (68-MER), Light chain of Fab HCV3
Authors:Koirala, D, Lewicka, A, Koldobskaya, Y, Huang, H, Piccirilli, J.A.
Deposit date:2019-09-05
Release date:2019-12-04
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (2.75 Å)
Cite:Synthetic Antibody Binding to a Preorganized RNA Domain of Hepatitis C Virus Internal Ribosome Entry Site Inhibits Translation.
Acs Chem.Biol., 15, 2020
6XJW
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BU of 6xjw by Molmil
Crystal structure of a self-alkylating ribozyme - alkylated form without biotin moiety
Descriptor: 2-{[(4R)-4-hydroxyhexyl]oxy}ethyl pentanoate, Fab HAVx Heavy Chain, Fab HAVx Light Chain, ...
Authors:Koirala, D, Piccirilli, J.A.
Deposit date:2020-06-24
Release date:2022-01-19
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (1.918 Å)
Cite:Structural basis for substrate binding and catalysis by a self-alkylating ribozyme.
Nat.Chem.Biol., 18, 2022
6XJZ
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BU of 6xjz by Molmil
Crystal structure of a self-alkylating ribozyme - apo form
Descriptor: Fab HAVx Heavy Chain, Fab HAVx Light Chain, Self-alkylating ribozyme (58-MER)
Authors:Koirala, D, Piccirilli, J.A.
Deposit date:2020-06-24
Release date:2022-01-19
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (2.488 Å)
Cite:Structural basis for substrate binding and catalysis by a self-alkylating ribozyme.
Nat.Chem.Biol., 18, 2022
6XJQ
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BU of 6xjq by Molmil
Crystal structure of a self-alkylating ribozyme - alkylated form with biotinylated epoxide substrate
Descriptor: 2-{[(4R)-4-hydroxyhexyl]oxy}ethyl 5-[(3aS,4S,6aR)-2-oxohexahydro-1H-thieno[3,4-d]imidazol-4-yl]pentanoate, Fab HAVx Heavy Chain, Fab HAVx Light Chain, ...
Authors:Koirala, D, Piccirilli, J.A.
Deposit date:2020-06-24
Release date:2022-01-19
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (1.708 Å)
Cite:Structural basis for substrate binding and catalysis by a self-alkylating ribozyme.
Nat.Chem.Biol., 18, 2022
6XJY
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BU of 6xjy by Molmil
Crystal structure of a self-alkylating ribozyme - short time incubation with the epoxide substrate
Descriptor: Fab HAVx Heavy Chain, Fab HAVx Light Chain, Self-alkylating ribozyme (58-MER)
Authors:Koirala, D, Piccirilli, J.A.
Deposit date:2020-06-24
Release date:2022-01-19
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (2.156 Å)
Cite:Structural basis for substrate binding and catalysis by a self-alkylating ribozyme.
Nat.Chem.Biol., 18, 2022
6MWN
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BU of 6mwn by Molmil
Crystal structure of hepatitis A virus IRES domain V in complex with Fab HAVx
Descriptor: Fab HAVx Heavy Chain, Fab HAVx Light Chain, HAV dV RNA (92-MER)
Authors:Koirala, D, Shao, Y, Piccirilli, J.A.
Deposit date:2018-10-29
Release date:2019-08-14
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (2.838 Å)
Cite:A conserved RNA structural motif for organizing topology within picornaviral internal ribosome entry sites.
Nat Commun, 10, 2019
6U8D
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BU of 6u8d by Molmil
Crystal structure of hepatitis C virus IRES junction IIIabc in complex with Fab HCV2
Descriptor: Heavy chain of Fab HCV2, JIIIabc RNA (68-MER), Light chain of Fab HCV2
Authors:Koirala, D, Lewicka, A, Koldobskaya, Y, Huang, H, Piccirilli, J.A.
Deposit date:2019-09-04
Release date:2019-12-04
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (1.807 Å)
Cite:Synthetic Antibody Binding to a Preorganized RNA Domain of Hepatitis C Virus Internal Ribosome Entry Site Inhibits Translation.
Acs Chem.Biol., 15, 2020
8DP3
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BU of 8dp3 by Molmil
Crystal structure of coxsackievirus B3 cloverleaf RNA replication element
Descriptor: Fab BL3-6 Heavy Chain, Fab BL3-6 Light Chain, PHOSPHATE ION, ...
Authors:Das, N.K, Koirala, D.
Deposit date:2022-07-14
Release date:2023-04-19
Last modified:2023-10-25
Method:X-RAY DIFFRACTION (1.91 Å)
Cite:Crystal structure of a highly conserved enteroviral 5' cloverleaf RNA replication element.
Nat Commun, 14, 2023
8T2A
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BU of 8t2a by Molmil
Crystal structure of SCV PTE G18A mutant RNA in complex with Fab BL3-6
Descriptor: BL3-6 Fab heavy chain, BL3-6 Fab light chain, RNA (90-MER)
Authors:Ojha, M, Koirala, D.
Deposit date:2023-06-05
Release date:2024-01-10
Method:X-RAY DIFFRACTION (3.17 Å)
Cite:Crystal structure of SCV PTE G18A mutant RNA in complex with Fab BL3-6
To Be Published
8T29
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BU of 8t29 by Molmil
Crystal structure of SCV PTE RNA in complex with Fab BL3-6
Descriptor: BL3-6 Fab heavy chain, BL3-6 Fab light chain, RNA (90-MER)
Authors:Ojha, M, Koirala, D.
Deposit date:2023-06-05
Release date:2024-01-10
Method:X-RAY DIFFRACTION (3.13 Å)
Cite:Crystal structure of SCV PTE RNA in complex with Fab BL3-6
To Be Published
8T2B
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BU of 8t2b by Molmil
Crystal structure of SCV PTE G18C mutant RNA in complex with Fab BL3-6
Descriptor: BL3-6 Fab heavy chain, BL3-6 Fab light chain, RNA (90-MER)
Authors:Ojha, M, Koirala, D.
Deposit date:2023-06-05
Release date:2024-01-10
Method:X-RAY DIFFRACTION (3.18 Å)
Cite:Crystal structure of SCV PTE G18C mutant RNA in complex with Fab BL3-6
To Be Published
8T2O
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BU of 8t2o by Molmil
Crystal structure of SCV PTE G18U RNA in complex with Fab BL3-6
Descriptor: BL3-6 Fab heavy chain, BL3-6 Fab light chain, RNA (90-MER)
Authors:Ojha, M, Koirala, D.
Deposit date:2023-06-06
Release date:2024-01-10
Method:X-RAY DIFFRACTION (3.29 Å)
Cite:Crystal structure of SCV PTE G18U RNA in complex with Fab BL3-6
To Be Published
6B3K
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BU of 6b3k by Molmil
Crystal structure of mutant Spinach RNA aptamer in complex with Fab BL3-6
Descriptor: Heavy chain of Fab BL3-6, Light chain of Fab BL3-6, MAGNESIUM ION, ...
Authors:DasGupta, S, Koirala, D, Shelke, S.A, Piccirilli, J.A.
Deposit date:2017-09-22
Release date:2017-12-27
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (2.09 Å)
Cite:Affinity maturation of a portable Fab-RNA module for chaperone-assisted RNA crystallography.
Nucleic Acids Res., 46, 2018

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