6XJY

Crystal structure of a self-alkylating ribozyme - short time incubation with the epoxide substrate

Summary for 6XJY

Entry DOI	10.2210/pdb6xjy/pdb
Descriptor	Self-alkylating ribozyme (58-MER), Fab HAVx Heavy Chain, Fab HAVx Light Chain, ... (4 entities in total)
Functional Keywords	self-alkylating ribozyme, antibody-assisted rna crystallography, rna catalysis, rna-immune system complex, rna/immune system
Biological source	Homo sapiens (Human) More
Total number of polymer chains	6
Total formula weight	145227.39
Authors	Koirala, D.,Piccirilli, J.A. (deposition date: 2020-06-24, release date: 2022-01-19, Last modification date: 2023-10-18)
Primary citation	Krochmal, D.,Shao, Y.,Li, N.S.,DasGupta, S.,Shelke, S.A.,Koirala, D.,Piccirilli, J.A. Structural basis for substrate binding and catalysis by a self-alkylating ribozyme. Nat.Chem.Biol., 18:376-384, 2022 Cited by PubMed: 35058645 DOI: 10.1038/s41589-021-00950-z PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.156 Å)

Structure validation