8GPK

Crystal structure of human anti-HIV-1 broadly neutralizing antibody F6 Fab

This is a non-PDB format compatible entry.

Summary for 8GPK

• Entry DOI: 10.2210/pdb8gpk/pdb
• EMDB information: 34190 34192 34193 34194
• Descriptor: F6 Fab heavy Chain, F6 Fab light chain (2 entities in total)
• Functional Keywords: antibody, fab, hiv-1, env binding, immune system
• Biological source: Homo sapiens; More
• Total number of polymer chains: 4
• Total formula weight: 98887.39

Authors

Niu, J.,Yang, B. (deposition date: 2022-08-26, release date: 2023-08-09, Last modification date: 2023-08-30)

• Primary citation: Niu, J.,Wang, Q.,Zhao, W.,Meng, B.,Xu, Y.,Zhang, X.,Feng, Y.,Qi, Q.,Hao, Y.,Zhang, X.,Liu, Y.,Xiang, J.,Shao, Y.,Yang, B.; Structures and immune recognition of Env trimers from two Asia prevalent HIV-1 CRFs.; Nat Commun, 14:4676-4676, 2023; PubMed: 37542068; DOI: 10.1038/s41467-023-40321-x

Experimental method

X-RAY DIFFRACTION (3.34 Å)